MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Breast Cancer Blog: Estrogen To Kill Cancer Cells!

Return to Breast Cancer Blog Main Cancer Blog Breast Cancer Main Page  

Dec 6, 2005

Estrogen To Kill Cancer Cells!

Estrogen To Kill Cancer Cells!
It is believed that the female hormone estrogen plays a big role in the development of breast cancer. The longer a woman gets exposure to estrogen hormone, higher is her risk of developing breast cancer. Early onset of menstruation (menarche) and late onset of menopause are both associated with increased risk of breast cancer because it simply prolongs the time of exposure to the estrogen.

Now researchers from Fox Chase Cancer Center In Philadelphia say that the same estrogen, which may be responsible for initiation of breast cancer, can be used to kill the breast cancer cells. These researchers uncovered new details about how estrogen can activate natural pathways. that kill certain breast cancer cells or tumors. The results raise the possibility that estrogen therapy may overcome resistance to certain breast cancer hormonal therapies. The study appears in the December 7 issue of the Journal of the National Cancer Institute.


Many breast cancer cells require estrogen for survival, and death of such cells can be induced with treatments that block estrogen, such as tamoxifen, fulvestrant, or aromatase inhibitors. When such treatments drain even the last drop of estrogen some of the breast cancer cells adapt to survival in an environment that is lacking estrogen. To best adapt to the environment these cells may lose its ability to live in the presence of estrogen. Paradoxically these cells may undergo rapid death when exposed to estrogen.

This new finding has important implications to breast cancer patients. When a woman who is using aromatase inhibitors like arimidex or femara fail on these drugs due to development of resistance, a strategy of treatment with estrogen may be developed to overcome the resistance and to kill these resistant breast cancer cells.

Emily      


Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      


Breast cancer
Every year, more than 200,000 women are diagnosed with breast cancer in the United States. Breast cancer ranks second as the leading cause of cancer deaths in American women. Until recently breast cancer topped the list of leading causes of cancer deaths in women, but lately lung cancer has claimed the top position. If skin cancer is excluded, breast cancer is the commonest cancer among American women.

Breast Cancer Blog: Estrogen To Kill Cancer Cells!

BREAST CANCER MAIN| Home| Breast cancer news| Common terms| Breast cancer symptoms| Mammogram and breast cancer screening| Treatment by stage| Surgical treatment| Chemotherapy| Chemo drugs| Doxorubicin| Cyclophosphamide| Methotrexate| Hormonal therapy| Radiation therapy| Monoclonal therapy| High dose chemotherapy| Recurrent breast cancer| Bisphosphonates| Pregnancy and breast cancer| Risk factors| Risk details| My risk| Comprehensive| Breast cancer statistics| African Americans| Ashkenazi| Asians| Hispanic| Men| Native Americans| Older women| Younger women| Pregnant women| BRCA|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.