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Diabetes Watch Blog: Insulin Patch Closer To FDA Approval

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Dec 9, 2005

Insulin Patch Closer To FDA Approval

Insulin Patch Closer To FDA Approval
I have previously written about inhaled form of insulin, today I am I writing about Insulin patch, which is a novel mode of delivery for insulin. Delivery of drugs through skin patches is not a new idea. You may be familiar with the nicotine patch that is used by smokers to help them to quit smoking. Duragesic patch is a commonly used morphine type of patch, commonly used in patients who have chronic pain like cancer patients. Insulin patches pretty much borrow the same idea.

Various types of insulin patches are under development by different pharmaceutical manufactures. Dermisonics Inc. is developing a new, ultrasonic transdermal drug-delivery patch and the company has recently announced that it has received approval from the regulatory authorities to enter into the next stage of human pilot trials of its proprietary U-Strip (TM) Insulin Patch drug-delivery system.

The trials, expected to begin in the first quarter of 2006, will evaluate the use of U-Strip transdermal patch device as an insulin delivery system for Type-2 diabetics.

If successful, it would add this painless and convenient alternative strategy to the armamentarium of the currently existing 175 or more drug formulations to treat diabetes.

The initial pilot study would involve a small group of volunteers with Type-2 diabetes, to compare the performance of the Dermisonics U-Strip (TM) Insulin Patch system with an existing FDA-approved insulin pump delivery system. The test will run for approximately three months. The study will evaluate the effectiveness of the Insulin Patch in comparison to conventional pump therapy, with one significant advantage; the U-Strip(TM) Insulin Patch will be totally non-invasive. The results of the study are expected to be available by 2006.


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Type-2 Diabetes
Type-2 diabetes is the most common form of diabetes, accounting for 90% of cases diabetes. This disease affects nearly 17 million Americans and is the seventh leading cause of death in the United States. Even though 17 million Americans have type-2 diabetes only half of these people are aware that they have diabetes. The death rate in patients with diabetes may be up to 11 times higher than in persons without the disease. The occurrence of diabetes in persons 45 to 64 years of age is 7 percent, but the proportion increases significantly in persons 65 years of age or older. Type-2 diabetes accounts for more than 90% of all diabetes worldwide.

Diabetes Watch Blog: Insulin Patch Closer To FDA Approval

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