Dec 5, 2005

Looking Forward To The Inhaled Form Of Insulin

Every one of us knows, how painful is the daily life of a diabetic patient. The more you would like to control your blood sugar, the more painful our lives become. Life stretches through the dark tunnel of pain and discomfort for most diabetic patients. But there is light at the end of the tunnel. The new inhaled formulations of insulin are instilling hope to all of us. After all there is light at the end of the tunnel.

There is clear evidence from clinical trials that a new inhaled formulation of insulin, Exubera, is as effective as traditional subcutaneous injections in controlling blood glucose in patients with type 1 or type 2 diabetes. The new formulation, is likely to be the first non-injectable insulin on the market.

Recent clinical trial results with Exubera are reviewed in the journal Core Evidence. Researchers say that one reason that clinicians and patients are often reluctant to initiate insulin therapy is due to the burden of daily injections, and the risk of low blood sugar and weight gain.
Exubera is a dry powder formulation packaged into blisters and delivered via a hand-held inhaler device developed by Nektar Therapeutics. It is jointly developed by Pfizer and Sanofi-Aventis. Its approval has been recommended by an FDA Advisory Board in the United States, and by the Committee for Medicinal Products for Human Use of the European Medicines Agency.

The review in Core Evidence states that there is clear evidence that Exubera is as effective as subcutaneous insulin in reducing HbA1c levels, which is the key indicator of blood glucose control, in patients with type 1 or type 2 diabetes. The article also found that "inhaled insulin" had a greater acceptance relating to convenience and ease of use." The incidence of weight gain and hypoglycemia was no greater with Exubera compared with subcutaneous insulin, and in short-term trials there was no effect on pulmonary function.

JoAnn      

Do You Read All Of Our Cancer Blogs?

Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      

Type-2 Diabetes
Type-2 diabetes is the most common form of diabetes, accounting for 90% of cases diabetes. This disease affects nearly 17 million Americans and is the seventh leading cause of death in the United States. Even though 17 million Americans have type-2 diabetes only half of these people are aware that they have diabetes. The death rate in patients with diabetes may be up to 11 times higher than in persons without the disease. The occurrence of diabetes in persons 45 to 64 years of age is 7 percent, but the proportion increases significantly in persons 65 years of age or older. Type-2 diabetes accounts for more than 90% of all diabetes worldwide.