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Cancer blog: Intraperitoneal Chemotherapy Improves Survival In Ovarian Cancer

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Jan 6, 2006

Intraperitoneal Chemotherapy Improves Survival In Ovarian Cancer

Intraperitoneal Chemotherapy Improves Survival In Ovarian Cancer
Intraperitoneal Chemotherapy Extends Ovarian Cancer Survival Intraperitoneal method for delivering chemotherapy offers women with ovarian cancer the chance to live longer than standard treatment.

In an analysis evaluating the intraperitoneal (through the abdomen) technique for delivering chemotherapy to the more commonly used intravenous chemotherapy, researchers established that average survival time for women with stage III ovarian cancer could be increased by nearly 16 months - to an average of 65.6 months - with intraperitoneal therapy.

Dr. Deborah Armstrong, an associate professor oncology and gynecology and obstetrics at Johns Hopkins Kimmel Cancer Center in Baltimore stated that this is the longest survival reported to date for advanced ovarian cancer.

Intraperitoneal chemotherapy is infused straight into the abdomen through a catheter surgically located under the skin. Armstrong said the catheter is normally placed beneath the lower left rib cage. Because the drug is going directly to the area affected by the cancer, rather than throughout the body, elevated doses of chemotherapy can often be used.

Women getting intraperitoneal chemotherapy are more likely to have side effects, such as gastrointestinal complexity, hematological troubles, infection, fatigue, pain and neurological problems. The average survival times were appreciably increased for these women.

Dr. Stephen Cannistra, director of gynecologic medical oncology at Beth Israel Deaconess Medical Center in Boston, wrote a supplementary editorial in the New England journal of Medicine. He said, "We are slowly but surely making progress against this terrible disease."


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Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.

Cancer blog: Intraperitoneal Chemotherapy Improves Survival In Ovarian Cancer

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