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Cancer blog: Amifostine Makes Radiation More Effective, Eases Side Effects

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March 6, 2006

Amifostine Makes Radiation More Effective, Eases Side Effects

Amifostine Makes Radiation More Effective, Eases Side Effects
The drug amifostine (Ethyol) is commonly used by radiation oncologist to decrease the side effects associated with radiation therapy. This drug is especially used in patients with head and neck cancer who may develop significant side effects due to radiation in the throat area.

In a new study researchers from Brazil have concluded that this drug amifostine eases many of the most common side effects associated with patients receiving radiation. The researchers also found that treatment with amifostine can make cancer cells more susceptible to radiation. This study was published in the recent issue of the International Journal of Radiation Oncology, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.

These researchers evaluated their theory, via a clinical investigation of already published work, whether adding amifostine to radiation therapy would prevent common side effects, such as mouth dryness, difficulty swallowing, lung inflammation, bladder inflammation, problems with the esophagus and inflammation of the mucous membranes. The researchers also wanted to find out if by reducing the side effects amifostine is inadvertently protecting the tumor from radiation.

The study is based on evaluation of 14 randomized, controlled clinical trials involving 1,451 patients. Patients were split into two groups: one receiving radiation therapy alone and the second receiving radiation therapy in addition to amifostine. Patients taking amifostine were shown to have less radiation-related side effects. The research also showed that the drug did not protect the tumor from the radiation therapy, on the other hand, patients receiving the drug were more likely to have their cancer affected by the radiation than patients not given amifostine.

Janet      



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Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

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Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      


b>Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable

Cancer blog: Amifostine Makes Radiation More Effective, Eases Side Effects

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