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Cancer blog: Ligt That Seeks Cancer Cells

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March 10, 2006

Ligt That Seeks Cancer Cells

Ligt That Seeks Cancer Cells
Image courtesy of Optics Express
A novel device that could use light to harmlessly and almost instantly probe for early signs of cancer has been developed by scientists at Duke's Pratt School of Engineering. The device would allow physicians to search for cancer in epithelial cells that line body surfaces, including the skin, lungs and digestive and reproductive tracts, by simply inserting a fiber optic probe.

The team has reported the first clinically practical version of their "angle-resolved low coherence interferometry" (a/LCI) technology designed to diagnose incipient cancer in the esophagus. Adam Wax, professor of biomedical engineering at the Pratt School, and graduate student John Pyhtila, lead author of the study, reported tests of their device in the March 15, 2006, Optics Letters. The work was supported by the National Institutes of Health and the National Science Foundation.

Preliminary results of a further study of the latest a/LCI device in human esophageal tissue look promising, Wax said. The next step will be to test the device in human trials.

In principle, the scientists said their technology could be adapted to detect pre-malignant cells on the surfaces of any organ, where the disease most often begins.

"The majority of all cancers - some 80 percent - start in the epithelium," Wax said. "Fiber-optic probes have the potential to test for early evidence of cancer in seconds, providing biopsy-type information without removing tissue. They could also serve as a guide to biopsy, directing physicians to suspicious sites to increase the likelihood that cancer will be detected." Biopsy surveillance in the esophagus removes tissue at random, he said.

Acid reflux can lead to changes in the esophageal lining as the organ attempts to adapt to acids normally limited to the stomach, a condition called Barrett's esophagus, he explained. The condition raises the risk of esophageal cancer, and patients are generally tested for cancer periodically through random biopsy.

Prior studies by Wax's team used a/LCI to identify pre-cancer in animal tissue. Typically pre-malignant cells are characterized by an enlarged nucleus, the structure that houses the cell's genetic material. It is such cellular changes that pathologists rely on to identify cancer in biopsied tissue, Wax said. Read more...... Source

Janet      



Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      


b>Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable

Cancer blog: Ligt That Seeks Cancer Cells

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