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Cancer blog: Mimicking Pregnancy To Reduce Breast Cancer Risk

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Nov 5, 2005

Mimicking Pregnancy To Reduce Breast Cancer Risk

Mimicing Pregnancy To Reduce Breast Cancer Risk
Women who had at least one pregnancy have much less risk of developing breast cancer compared to women who have never been pregnant. Earlier during the course of the reproductive life the woman gets pregnant, higher are her chances of preventing breast cancer. The question is: can you mimic pregnancy to escape developing breast cancer and that is exactly what the researchers are asking.

Now, some researchers who gathered in Baltimore for the Frontiers in Cancer Prevention Research conference say they may have found a way to mimic nature and reduce the risk f breast cancer for all women.

The caveat however is that they have so far experimented this new technique only in mice. Mice, as you know after all, are not human being and naturally clinical trial have to be conducted in women before this new method cancer can be used in women. These researchers are particularly hopeful that this research will prove to be effective in women.

This is the theory of breast cancer prevention by mimicking pregnancy: when a woman becomes pregnant the fetus produces a protein called alpha feto protein (AFP). This protein is capable of reducing mother's breast cancer risk later in life.

The protective effect of breast cancer is apparent after each time a woman becomes pregnant. The younger she is the first time, the greater the benefit. Having twins or triplets increases the beneficial effect. Women who become pregnant at age of 20 have about half the risk of breast cancer as a woman whose first pregnancy occurs at 26 or later.

Researchers from Albany Medical College have produced a molecule with the same chemical characteristics as AFP and gave it to thousands of mice that had been implanted with breast cancer cells. The research team found that this compound, AFPep, stopped the growth of the cancer cells and reduced the number of tumors in the mice by 23 percent.

When AFPep was combined with tamoxifen - a drug now used to treat breast cancer - it reduced tumors by 77 percent.

"This is a new proposal and a brand new way of looking at breast cancer treatment," said Thomas T. Andersen, a biochemist and cancer researcher at the medical college.

Let's hope this will pan out to be a reliable breast cancer prevention method in human beings.

Janet      Return to Cancer Blog Main

Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer. publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.


We do not know the exact cause of many cancers. Many cancers like leukemia have no apparent cause. Some other types of cancers like lung cancers have identifiable causes like smoking in most cases. Lung cancer can occur in those who have never smoked in their life. It is hard to know in these cases what is causing that patients lung cancer. Factors that increase the risk of development of cancer is known as risk factors for cancer. These risk factors may be modifiable like smoking where a person can exert control or un-modifiable factors like age and gender. Smoking can cause cancers of the lungs, mouth, throat, bladder, kidneys and several other organs.

Cancer blog: Mimicking Pregnancy To Reduce Breast Cancer Risk

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