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Cancer blog: New Cancer Detection Technique In The Horizon

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Nov 29, 2005

New Cancer Detection Technique In The Horizon

New Cancer Detection Technique In The Horizon
Researchers from the University of Florida claim that they are a step closer to a technique to easily detect a wide variety of cancers before symptoms become apparent. This technique could enable doctors to search within extremely complex fluid or tissue samples to pinpoint biomarkers, proteins that signal that something is amiss.

Findings of the UF researchers are published in the Proceedings of the National Academy of Sciences, and involve introducing molecularly engineered strands of DNA into cell cultures and observing whether they unleash a fluorescent burst after they adhere to cancer proteins.

"Even when the cancer biomarkers are in extremely low concentration we have been able to detect them," said Weihong Tan, a UF Research Foundation professor of chemistry in the College of Liberal Arts and Sciences and a member of the UF Genetics Institute, the UF Shands Cancer Center and the McKnight Brain Institute. "This approach could help for early diagnosis of cancer, as well as for detecting residual cancer in patients after treatment."

It works by capitalizing on fluorescent molecules engineered into tiny strands of DNA or RNA. Known as aptamers, the strands act as molecular beacons, corresponding and readily binding to a sought-after substance such as cancer protein.

In this case, the target was platelet derived growth factor, or PDGF, a protein that regulates cell growth and division. Elevated PDGF levels have been linked to different forms of cancer, and have been found in patients with malignancies of the ovaries, kidneys, lung, pancreas and brain.

After the probe physically conforms to the PDGF, the molecule can be snapped on like a light switch to flash a fluorescent signal.


Janet      Return to Cancer Blog Main


Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      


Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.

Cancer blog: New Cancer Detection Technique In The Horizon

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