From Medicineworld.org: Cancer blog
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.
Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.
Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.
Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.
Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.
Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.
Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.
Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.
Patients who took Temodal and received radiation therapy after surgical removal of their tumor showed an 18.3-month median survival, compared with 14.2 months for those on radiation therapy alone after surgery.
"Our expectations were exceeded in this study, particularly among patients who underwent complete resection followed by Temodal and radiation therapy," said Dr. Martin van den Bent, head of the neuro-oncology unit at the Daniel den Hoed Cancer Center in Rotterdam.
The study, presented at the 13th European Cancer Conference (ECCO 13), was conducted by the European Organization for Research and Treatment of Cancer and the National Cancer Institute of Canada Clinical Trials Group.
Surgery included complete tumor removal among almost 40 percent of the patients in the trial, partial removal among 44 percent and biopsy among 16 percent of the patients, Schering said. In all cases Temodal along with radiation improved survival versus radiation therapy alone.
Improvement was also demonstrated in two-year survival rates among patients who underwent complete tumor removal surgery - showing that just over 37 percent of the patients on Temodal survived compared with 14.5 percent of those on radiation only.
Understanding the structure of the ADAM10 molecule provides the basis for developing pharmaceutical drugs to inhibit tumor growth and metastasis, the spreading of cancerous tumor cells throughout the body.
The authors believe the findings alter the predominant perception of the way cell signaling molecules, such as growth factor and cell positioning receptors, communicate and regulate processes such as cell adhesion and motility. Although scientists knew ADAM10 was crucial to tumor growth, how it actually operated to control other molecules was unclear.
"We discovered that ADAM10 specifically recognized only Eph and Ephrin molecules that were actively engaged in signaling, and by manipulating the ADAM structure were able to interfere with this molecular recognition and arrest signaling," said senior research fellow Dr Martin Lackmann from Monash's Department of Biochemistry and Molecular Biology. "Being able to regulate the communication between these cell surface molecules, which are found at high levels in many human cancers, by preventing the function of ADAM, may actually stop the growth and spread of tumors."
Dr Chris IR Gill, one of the researchers, explained: "Because the colon is one of the major cancer sites thought to be protected by olive oil, the UU research team studied the potential anti-cancer effects of virgin olive chemical compounds in cultured cell lines widely used as models for colorectal cancer.
"We found that incubation of one cancer cell line with increasing concentrations of olive oil phenols for 24 hours protected the cells from DNA damage. The effect of olive oil phenols on another cell line after 48 hours of exposure suggested that they 'may exert an anti-promoter effect in the carcinogenesis pathway'.
"While the findings are purely of an experimental nature, they identify mechanisms that support the scientific and medical evidence suggesting an association between olive oil consumption and decreased risk of cancer.
"The research shows that the effect is not only related to the types of fat present in the oil but also the phenolic compounds present. The next stage is to assess the effects in a suitable animal model."
The findings will be published in this month's International Journal of Cancer.
Breast cancer continues to be a major health problem among women in the United States and across the globe. American Cancer Society estimates that 215,990 women and 1,450 men will have the diagnosis of breast cancer by the end of this year. An estimated 40,110 women and 470 men will die from breast cancer this year.
We have seen marked increase in the incidence of breast cancer over the last few years but finally now the incidence of breast cancer is leveling off in white women (data not available for other women).
Prevention is the best strategy against breast cancer. There are several proven risk factors that may increase the risk of breast cancer. This includes postmenopausal estrogen use, use of excess alcohol, smoking, high fat diet and lack of exercises. Since prevention is not always possible early detection is very important in breast cancer. If detected at very early stage and treated properly, you may expect to have a 5-year survival of 98 percent.
Breast cancer usually affects women who are older than 50 years, and more than 75 percent of all breast cancers occur in this age group. African American women generally have a higher rate of breast cancer mortality compared to Caucasian women. African American women aged between 30 and 69 have the highest breast cancer mortality rates. For women ages 70 and over, mortality rates are highest among white women.
Only about 5 percent of all breast cancers have a demonstrable inherited genetic abnormality like BRCA mutation, but diagnosis of breast cancer in a first degree relative increases your risk of breast cancer.
All women should start self-examination of the breast at age 20 and should start screening with mammogram at 40. Women who have increased risk of breast cancer may start screening at an earlier age.
As the breast cancer awareness month is coming to a close let's learn the key points about breast cancer and discuss with our friends.
"This is amazing," says Michael Heinrich, a professor at the Oregon Health and Science University Cancer Institute, who was not involved in the study. "This is the Rosetta Stone of prostate cancer. Cracking the code lets you read the whole library. The implications of this are huge in a lot of different ways."
These research findings were published in the recent issue of the journal Science. This study may form a foundation for further cancer research as per one of the study's authors, Mark Rubin, chief of urologic pathology at Brigham and Women's Hospital in Boston.
This finding is revolutionary in the fact that until now researchers were thinking that prostate cancer is the result of lots of random genetic mutations. This study, however, suggests for the first time that prostate cancer begins after specific genes fuse, forming a complex gene promoting growth of prostate cancer. This merged gene was detectable in nearly 80% of 29 prostate cancer samples, says Arul Chinnaiyan, a professor at the University of Michigan Medical School who directed the study. None of the 50 samples of non-cancerous tissue had the genes, he says.
This discovery may allow doctors to begin to divide prostate cancer - which is now treated as a single disease - into different types which could lead to more targeted therapies based on the genetic abnormalities.
Several previous studies have suggested that cruciferous vegetables like cabbage, broccoli and sprouts, protected against lung cancer. However, these previous studies were not large enough draw any definite conclusion, the authors of the new research said.
"We found protective effects with at least weekly consumption of cruciferous vegetables," said Paul Brennan, lead author of a research letter that appeared in the latest issue of The Lancet. Brennan is head of the Genetic Epidemiology Group at the International Agency for Research on Cancer in Lyon, France.
The protective effect of cruciferous vegetables is related to their rich content of isothiocyanates, which have been demonstrated to have a chemopreventive effect against lung cancer.
This results are from a large study consisting of 2,141 people with lung cancer, comparing them with 2,168 healthy individuals in the Czech Republic, Hungary, Poland, Slovakia, Romania and Russia, where consumption of these vegetables has traditionally been high.
In this study which was sponsored by National Cancer Institute the researchers demonstrated that screening with mammography is responsible for about 46 percent of the decline in the death rate from breast cancer, while adjuvant treatments such as chemotherapy and tamoxifen are responsible for an estimated 54 percent of the reduction in deaths.
"The average woman can gain some comfort knowing that both these things that are going on are important," said study co-author Donald Berry, chairman of the department of biostatistics and applied mathematics at the University of Texas M.D. Anderson Cancer Center in Houston.
The results of this study should help lay to rest arguments over the benefits and risks of mammograms, the screening tests that can spot tumors while small and curable. Some experts say that mammograms were unlikely to be very effective and that it was a waste of money and resources to have every woman 40 and older have one each year. Other experts say that mammograms were crucial and that without screening to find cancer early, the treatments would not be nearly as effective.
Dr. Russell Harris, a professor of medicine at the University of North Carolina and a member of the United States Preventive Services Task Force, which issues medical practice guidelines, said the new finding means that women can feel confident that the screening plays a role in preventing breast cancer deaths.
This is a multi-center phase 2 clinical trial designed to determine the safety, efficacy, tolerability and pharmcokinetc profile and biological activity of AMN107.
For more information contact: 1-800-340-6843
These are the findings from a study conducted by Norbert Avril MD and colleagues from the University of Pittsburgh Medical Center in Pa. The researchers have found that the FDG-PET activity after chemotherapy strongly correlated with overall prognosis and survival. This predictive value of FDG-PET started with the first course of treatment and was apparent to the third course of treatment. Patients who had response in FDG-PET had survived about15.2 months longer than those who never had an FDG-PET response. A total of 73 percent of patients who had FDG-PET scan response survived 2 years while only 45.5 percent of non-FDG-PET responders survived 2 years.
The study enrolled 51 patients to receive treatment with paclitaxel and carboplatin followed by radiation therapy with concurrent efaproxiral.
After two months of follow up, the disease progressed in two patients and remained stable in three patients. Seven patients were not evaluated for various reasons. Three patients achieved complete disappearance of the tumor and 34 patients achieved reduction of tumor size to at least 50 percent of the original size. This would amount to an overall response rate of 75 percent.
The researchers compared the survival of these patients to survival in RTOG-94-10, which enrolled patients with similar chrematistics and found that the median survival of 20.6 months observed in the current study was longer than 17.9 months as reported in RTOG-94-10.
The results of this trial should be interpreted with caution since this is small phase II study and selection bias may have influenced the treatment outcome. Results need to be confirmed in a larger randomized clinical trial.
The ingredients in walnuts may reduce incidence of cancer, degenerative nerve diseases of aging including Alzheimer's disease, Parkinsonism and may reduce severity of cardiovascular diseases as per Russel J. Reiter, PhD., who is a professor of neuroendocrinology at University of Texas Health Science Center. These findings were published in the recent issue of the "International Journal of Applied and Basic Nutritional Science."
When walnuts are consumed, it increases blood levels of melatonin by three fold as per the research findings. Studies have shown that walnuts reduce the risk of heart disease due to the presence of omega-3-fatty acids and antioxidants. Meltonin and omega-3-fatty acids can lead to starving of the cancer cells thus preventing the growth of cancer clone. This combination of melatonin and omega-3-fatty acids that is present in walnut may be better suited for prevention of cancer compared to melatonin taken in a tablet form, as per Reiter.
Herceptin in action
Picture courtesy of herceptin.com
"This is probably the biggest evidence of a treatment effect I've ever seen in oncology", said Richard Gelber of the Dana-Farber Cancer Institute, said.
"The results are simply stunning," said Hortobagyi from the MD Anderson Cancer Center
Houston, TX and a leading breast cancer researcher. "All three trials show highly significant reductions in the risk of recurrence, of a magnitude seldom observed in oncology trials," he said.
The medical research community has greeted the results with uncommon enthusiasm.
When the preliminary findings were first released last May at the annual conference of the American Society of Clinical Oncology, attendees gave the presenters a standing ovation.
The significance is huge for women threatened by breast cancer, said doctor Martine Piccart, chairwoman of the Breast International Group.
Older blogs 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.
Medicineworld.org: Cancer blog
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.