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Do You Read All Of Our Blogs?

Do You Read All Of Blogs?
This page you have reached is an archive of old blog posting. Just follow the links below to go to the main blog pages to read the latest blog posting.

Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.

Janet      

Nov 1, 2005

Brain Cancer Drug With Radiation Improves Survival

Brain Cancer Drug With Radiation Improves Survival
Temozolomide also called Temodal is a oral chemotherapy drug that is used to treat primary cancer of the brain. A recent study has shown that Patients using Temodal along with radiation therapy after surgery for primary brain cancer may have prolonged survival.
Patients who took Temodal and received radiation therapy after surgical removal of their tumor showed an 18.3-month median survival, compared with 14.2 months for those on radiation therapy alone after surgery.

"Our expectations were exceeded in this study, particularly among patients who underwent complete resection followed by Temodal and radiation therapy," said Dr. Martin van den Bent, head of the neuro-oncology unit at the Daniel den Hoed Cancer Center in Rotterdam.

The study, presented at the 13th European Cancer Conference (ECCO 13), was conducted by the European Organization for Research and Treatment of Cancer and the National Cancer Institute of Canada Clinical Trials Group.

Surgery included complete tumor removal among almost 40 percent of the patients in the trial, partial removal among 44 percent and biopsy among 16 percent of the patients, Schering said. In all cases Temodal along with radiation improved survival versus radiation therapy alone.

Improvement was also demonstrated in two-year survival rates among patients who underwent complete tumor removal surgery - showing that just over 37 percent of the patients on Temodal survived compared with 14.5 percent of those on radiation only.

Janet      Permalink

Oct 31, 2005

Research Tell Us How Cancer Cells Communicate

Research Tell Us How Cancer Cells Communicate
Researchers at Monash University and the Sloan Kettering Cancer Center in New York, have uncovered the structure of the molecular switch that controls communication between tumor cells. The "switch" involves a cell-surface protease called ADAM10 that regulates the signals that promote tumor growth and motility of cancer cells.

Understanding the structure of the ADAM10 molecule provides the basis for developing pharmaceutical drugs to inhibit tumor growth and metastasis, the spreading of cancerous tumor cells throughout the body.

The authors believe the findings alter the predominant perception of the way cell signaling molecules, such as growth factor and cell positioning receptors, communicate and regulate processes such as cell adhesion and motility. Although scientists knew ADAM10 was crucial to tumor growth, how it actually operated to control other molecules was unclear.

"We discovered that ADAM10 specifically recognized only Eph and Ephrin molecules that were actively engaged in signaling, and by manipulating the ADAM structure were able to interfere with this molecular recognition and arrest signaling," said senior research fellow Dr Martin Lackmann from Monash's Department of Biochemistry and Molecular Biology. "Being able to regulate the communication between these cell surface molecules, which are found at high levels in many human cancers, by preventing the function of ADAM, may actually stop the growth and spread of tumors."

Janet      Permalink

Oct 31, 2005

Olive Oil Protects Against Colon Cancer

Olive Oil Protects Against Colon Cancer
Commonly used olive oil could be your next key weapon against colorectal cancer as per the results of a new study. Researchers from University of Ulster have found that special phenols extracted from olive oil could protect you from colorectal cancer. Researchers are well aware of the protective effects of the Mediterranean diet, which is rich in olive oil, in colon cancer protection. This research sheds light on this well know fact by identifying ways by which olive oil could provide protection and reduce the cancer risk.

Dr Chris IR Gill, one of the researchers, explained: "Because the colon is one of the major cancer sites thought to be protected by olive oil, the UU research team studied the potential anti-cancer effects of virgin olive chemical compounds in cultured cell lines widely used as models for colorectal cancer.

"We found that incubation of one cancer cell line with increasing concentrations of olive oil phenols for 24 hours protected the cells from DNA damage. The effect of olive oil phenols on another cell line after 48 hours of exposure suggested that they 'may exert an anti-promoter effect in the carcinogenesis pathway'.

"While the findings are purely of an experimental nature, they identify mechanisms that support the scientific and medical evidence suggesting an association between olive oil consumption and decreased risk of cancer.

"The research shows that the effect is not only related to the types of fat present in the oil but also the phenolic compounds present. The next stage is to assess the effects in a suitable animal model."

The findings will be published in this month's International Journal of Cancer.

Janet      Permalink

Oct 30, 2005

Final Days Of Breast Cancer Awareness Month

Final Days Of Breast Cancer Awareness Month
October is breast cancer awareness month and now it is coming to an end. At this time it may be important to ask ourselves what we have learned in the last month about breast cancer. At this time I would like to reiterate the key points regarding breast cancer.

Breast cancer continues to be a major health problem among women in the United States and across the globe. American Cancer Society estimates that 215,990 women and 1,450 men will have the diagnosis of breast cancer by the end of this year. An estimated 40,110 women and 470 men will die from breast cancer this year.

We have seen marked increase in the incidence of breast cancer over the last few years but finally now the incidence of breast cancer is leveling off in white women (data not available for other women).

Prevention is the best strategy against breast cancer. There are several proven risk factors that may increase the risk of breast cancer. This includes postmenopausal estrogen use, use of excess alcohol, smoking, high fat diet and lack of exercises. Since prevention is not always possible early detection is very important in breast cancer. If detected at very early stage and treated properly, you may expect to have a 5-year survival of 98 percent.

Breast cancer usually affects women who are older than 50 years, and more than 75 percent of all breast cancers occur in this age group. African American women generally have a higher rate of breast cancer mortality compared to Caucasian women. African American women aged between 30 and 69 have the highest breast cancer mortality rates. For women ages 70 and over, mortality rates are highest among white women.

Only about 5 percent of all breast cancers have a demonstrable inherited genetic abnormality like BRCA mutation, but diagnosis of breast cancer in a first degree relative increases your risk of breast cancer.

All women should start self-examination of the breast at age 20 and should start screening with mammogram at 40. Women who have increased risk of breast cancer may start screening at an earlier age.

As the breast cancer awareness month is coming to a close let's learn the key points about breast cancer and discuss with our friends.

Janet      Permalink

Oct 28, 2005

Genes Causing Prostate Cancer Developement Discovered

Genes Causing Prostate Cancer Developement Discovered
A key set of genes that is involved in the initiation and production of prostate cancer has been identified. Researchers hail this new finding as a breakthrough in prostate cancer research and say that this may lead to development of more effective diagnostic tests and treatment for prostate cancer.

"This is amazing," says Michael Heinrich, a professor at the Oregon Health and Science University Cancer Institute, who was not involved in the study. "This is the Rosetta Stone of prostate cancer. Cracking the code lets you read the whole library. The implications of this are huge in a lot of different ways."

These research findings were published in the recent issue of the journal Science. This study may form a foundation for further cancer research as per one of the study's authors, Mark Rubin, chief of urologic pathology at Brigham and Women's Hospital in Boston.

This finding is revolutionary in the fact that until now researchers were thinking that prostate cancer is the result of lots of random genetic mutations. This study, however, suggests for the first time that prostate cancer begins after specific genes fuse, forming a complex gene promoting growth of prostate cancer. This merged gene was detectable in nearly 80% of 29 prostate cancer samples, says Arul Chinnaiyan, a professor at the University of Michigan Medical School who directed the study. None of the 50 samples of non-cancerous tissue had the genes, he says.


This discovery may allow doctors to begin to divide prostate cancer - which is now treated as a single disease - into different types which could lead to more targeted therapies based on the genetic abnormalities.

Janet      Permalink

Oct 28, 2005

Vegitables That Protect Against Lung Cancer

MorVegitables That Protect Against Lung Cancer
Now there is ever more evidence for the protective effect of vegetables for lung cancer. A new study suggests that people who have genetic susceptibility to lung cancer may be able to cut down their risk of developing lung cancer by eating vegetables from the cabbage family.

Several previous studies have suggested that cruciferous vegetables like cabbage, broccoli and sprouts, protected against lung cancer. However, these previous studies were not large enough draw any definite conclusion, the authors of the new research said.


"We found protective effects with at least weekly consumption of cruciferous vegetables," said Paul Brennan, lead author of a research letter that appeared in the latest issue of The Lancet. Brennan is head of the Genetic Epidemiology Group at the International Agency for Research on Cancer in Lyon, France.

The protective effect of cruciferous vegetables is related to their rich content of isothiocyanates, which have been demonstrated to have a chemopreventive effect against lung cancer.

This results are from a large study consisting of 2,141 people with lung cancer, comparing them with 2,168 healthy individuals in the Czech Republic, Hungary, Poland, Slovakia, Romania and Russia, where consumption of these vegetables has traditionally been high.

Janet      Permalink

Oct 27, 2005

Proof: Mammogram Saves Lives

Proof: Mammogram Saves Lives
Now is the time to stop arguing about the benefits of mammograms in saving women's lives from breast cancer. Results of a new study shows that mammogram and powerful new drugs contributed to a drop in deaths from breast cancer in the last 25 years of the 20th century as per a study that was published in the latest issue of New England Journal of Medicine.

In this study which was sponsored by National Cancer Institute the researchers demonstrated that screening with mammography is responsible for about 46 percent of the decline in the death rate from breast cancer, while adjuvant treatments such as chemotherapy and tamoxifen are responsible for an estimated 54 percent of the reduction in deaths.

"The average woman can gain some comfort knowing that both these things that are going on are important," said study co-author Donald Berry, chairman of the department of biostatistics and applied mathematics at the University of Texas M.D. Anderson Cancer Center in Houston.


The results of this study should help lay to rest arguments over the benefits and risks of mammograms, the screening tests that can spot tumors while small and curable. Some experts say that mammograms were unlikely to be very effective and that it was a waste of money and resources to have every woman 40 and older have one each year. Other experts say that mammograms were crucial and that without screening to find cancer early, the treatments would not be nearly as effective.

Dr. Russell Harris, a professor of medicine at the University of North Carolina and a member of the United States Preventive Services Task Force, which issues medical practice guidelines, said the new finding means that women can feel confident that the screening plays a role in preventing breast cancer deaths.

Janet      Permalink

Oct 26, 2005

New Clinical Trial For Patients With Chronic Myeloid Leukemia

New Clinical Trial For Patients With Chronic Myeloid Leukemia
A new clinical trial is underway for patients with the diagnosis of Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML). This clinical trial is evaluating the efficiency of the new selective bcr-abl inhibitor AMN107 in patients who belongs to anyone of the following categories.
  1. Imatinib (gleevec) resistant or intolerant Ph+ patients who are in blast crisis
  2. Imatinib (gleevec) resistant or intolerant Ph+ patients who are in accelerated phase
  3. Imatinib (gleevec) resistant or intolerant Ph+ patients who are in the chronic phase of CML
  4. Relapsed or refractory Ph+ acute lymphocytic leukemia patients
  5. Hypereosinophilic syndrome or chronic eosinophilic leukemia
  6. Systemic matocytosis


This is a multi-center phase 2 clinical trial designed to determine the safety, efficacy, tolerability and pharmcokinetc profile and biological activity of AMN107.

For more information contact: 1-800-340-6843

Janet      Permalink

Oct 23, 2005

FDG-PET For Chemotherapy Follow Up Of Ovarian Cancer

FDG-PET For Chemotherapy Follow Up Of Ovarian Cancer
Physicians give chemotherapy to patients with locally advanced ovarian cancer with the idea of shrinking the tumor prior to surgery. Typically physicians would check, the level of CA-125 to see if the patient is responding to chemotherapy. New research shows that a FDG-PET scan has more predictive power compared to measurement of CA-125.

These are the findings from a study conducted by Norbert Avril MD and colleagues from the University of Pittsburgh Medical Center in Pa. The researchers have found that the FDG-PET activity after chemotherapy strongly correlated with overall prognosis and survival. This predictive value of FDG-PET started with the first course of treatment and was apparent to the third course of treatment. Patients who had response in FDG-PET had survived about15.2 months longer than those who never had an FDG-PET response. A total of 73 percent of patients who had FDG-PET scan response survived 2 years while only 45.5 percent of non-FDG-PET responders survived 2 years.

Janet      Permalink

Oct 21, 2005

Addition of Efaproxiral To Radiation Improves Survival in NSCLC

Addition of Efaproxiral To Radiation Improves Survival in NSCLC
Adding efaproxiral (Efaproxyn, RSR13) to radiation therapy after chemotherapy may improve outcome in patients with non-small cell lung cancer, which is irremovable by surgery as per a new study. This improvement in survival comes without increasing the toxicities with the addition of efaproxiral.

The study enrolled 51 patients to receive treatment with paclitaxel and carboplatin followed by radiation therapy with concurrent efaproxiral.

After two months of follow up, the disease progressed in two patients and remained stable in three patients. Seven patients were not evaluated for various reasons. Three patients achieved complete disappearance of the tumor and 34 patients achieved reduction of tumor size to at least 50 percent of the original size. This would amount to an overall response rate of 75 percent.

The researchers compared the survival of these patients to survival in RTOG-94-10, which enrolled patients with similar chrematistics and found that the median survival of 20.6 months observed in the current study was longer than 17.9 months as reported in RTOG-94-10.

The results of this trial should be interpreted with caution since this is small phase II study and selection bias may have influenced the treatment outcome. Results need to be confirmed in a larger randomized clinical trial.

Janet      Permalink

Oct 21, 2005

Walnuts May Halt Cancer And Heart Disease

Walnuts May Halt Cancer And Heart Disease
Research done at University of Texas Health Science Center at San Antonio has shown that walnuts contain plenty of melatonin. Melatonin is a powerful anti-oxidant and is capable of stopping diseases like cancer, heart disease and many diseases associated with aging.

The ingredients in walnuts may reduce incidence of cancer, degenerative nerve diseases of aging including Alzheimer's disease, Parkinsonism and may reduce severity of cardiovascular diseases as per Russel J. Reiter, PhD., who is a professor of neuroendocrinology at University of Texas Health Science Center. These findings were published in the recent issue of the "International Journal of Applied and Basic Nutritional Science."

When walnuts are consumed, it increases blood levels of melatonin by three fold as per the research findings. Studies have shown that walnuts reduce the risk of heart disease due to the presence of omega-3-fatty acids and antioxidants. Meltonin and omega-3-fatty acids can lead to starving of the cancer cells thus preventing the growth of cancer clone. This combination of melatonin and omega-3-fatty acids that is present in walnut may be better suited for prevention of cancer compared to melatonin taken in a tablet form, as per Reiter.

Janet      Permalink

Oct 20, 2005

Herceptin Results 'Simply Stunning': Breast Cancer Researhers

Herceptin Results 'Simply Stunning': Breast Cancer Researhers
Herceptin in action
Picture courtesy of herceptin.com
The results from herceptin (trastuzumab) in combination with chemotherapy is 'simply stunning' as per the leading breast cancer researchers. The clinical trial result released yesterday (see blog post from yesterday) is the third consecutive large trial that had consistently showed a fifty percent reduction in the risk of breast cancer recurrence with the use of herceptin in combination with chemotherapy in early stage breast cancer patients who have over expression of Her2 gene. With the new clinical trial results released there is now experience from 6,500 patients for the use of herceptin and chemotherapy in this group of patients.

"This is probably the biggest evidence of a treatment effect I've ever seen in oncology", said Richard Gelber of the Dana-Farber Cancer Institute, said.

"The results are simply stunning," said Hortobagyi from the MD Anderson Cancer Center
Houston, TX and a leading breast cancer researcher. "All three trials show highly significant reductions in the risk of recurrence, of a magnitude seldom observed in oncology trials," he said.

The medical research community has greeted the results with uncommon enthusiasm.

When the preliminary findings were first released last May at the annual conference of the American Society of Clinical Oncology, attendees gave the presenters a standing ovation.

The significance is huge for women threatened by breast cancer, said doctor Martine Piccart, chairwoman of the Breast International Group.

Janet      Permalink



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Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.

Medicineworld.org: Cancer blog

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