From Medicineworld.org: Cancer blog
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.
Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.
Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.
Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.
Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.
Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.
Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.
Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.
The local residents however were not very happy about this. They found out that there are 878 houses near Stirling which lie within 600 meters of the broad route proposed for the power line. That is the distance within which a recent government study found the risks of childhood leukemia increased.
Some experts say proximity to power lines is also linked to severe depression, suicide, miscarriages, brain cancer and motor neuron disease. Other countries have taken strict precautions against siting high-voltage pylons next to homes.
The most disturbing evidence to date on the health hazards of pylons comes from a study by the Childhood Cancer Research Group at Oxford University, published in the British Medical Journal in June. The study of 29,000 children in England and Wales found that those who lived within 200 meters of a high-voltage line had a 69% increased risk of leukemia. Those living 200 to 600 meters away had a 23% increased risk.
But Stirling Before Pylons says this is "misleading". The group counted 50 houses in the Stirling Council area alone within 100 metres of where pylons could be sited. Pylons could be put up anywhere inside a corridor that ranges from 100 to 400 metres wide, it claimed.
These findings were recently published in the journal Cancer Biology and Therapy. Researchers say that this may have implications for breast cancer, prostate cancer, lymphoma, myeloma and other hematologic cancers.
Paul Dent, Ph.D., associate professor of biochemistry and radiation oncology at VCU, led the team of researchers. In this new study, researchers combined two novel drugs, UCN-01 and a MEK 1/2 inhibitor, which are known to inhibit protein kinases, part of tumor survival signaling pathways.
"In addition to potently inhibiting cells and suppressing tumor growth, these drugs are also part of a modern class of drugs that are less toxic to non-cancerous cells," said Dent. "We are eager to move these exciting findings from the labs to patients."
When studied separately, the drugs only killed a small percent of the cells to which they were exposed. Combined, however, the result was quite startling.
"Within five days, we saw profound tumor cell death," Dent says.
This study is the first of its kind to examine the impact of prostate cancer on the employment status of men, shedding new light on how the physical effects of this cancer and its treatment may affect their livelihoods.
Now a little secret: about two-thirds of the patients who were still working said that they continued to work out of fear of losing health insurance coverage. (The insurance companies did not hear that.....)
"The fear of losing health insurance may have encouraged some patients who otherwise would have quit or retired to keep working," said Cathy J. Bradley, Ph.D., a health economist for the VCU Massey Cancer Center. "We saw an unemployment disparity among older, less-educated men."
Additionally, those still working decreased their weekly work hours by about four hours, and 43 percent of them said they were not able to work at their former capacity due to cancer treatment-related symptoms.
Breast cancer blog: Breast cancer blog is run by Janet. Latest breast cancer blog post reads as follows: FDA Issues Warning For Herceptin Plus Chemotherapy Combination - Genentec and FDA have issued a recent warning stating that combined use of herceptin (trastuzumab) and chemotherapy may significantly increase the risk of toxicity for the heart. Recent clinical trials have found that combination of herceptin with chemotherapy may improve disease free survival if used an adjuvant therapy in patients with early breast cancer, who over-expresses Her2 gene.....
Lung cancer blog: Lung cancer blog is run by Scott. Latest lung cancer blog post reads as follows: Chris Whitely Is Dying Of Lung Cancer - Chris Whitely, the famous singer and songwriter has been diagnosed with advanced lung cancer as per a posting on Blue star's official website. In this posting his brother Dan writes that the Chris Whitely's disease is in its late stages. He also says that Whitley is currently in home hospice care.....
Colon cancer blog: Colon cancer blog is run by Sue. Latest colon cancer blog post reads as follows: High-fat Dairy Food May Decrease Colorectal Cancer Risk - Eat lots of diary foods! That may be the latest message for those of us who are trying to prevent colorectal cancer. In those who make a habit of eating large amounts of high-fat dairy foods and conjugated linoleic acid (a component of dairy foods), may have a reduced risk of colorectal cancer according to Dr. Susanna C. Larsson from Karolinska Institute, Stockholm.....
Prostate cancer blog: Prostate cancer blog is run by Mark. Latest prostate cancer blog post reads as follows: One Pill A Day To Beat Prostate Cancer - It may be possible one day for some men to pop a pill each day to cut their chances of prostate cancer, as per some researches. These scientists used thousands of prostate biopsy samples to try to identify men at greater risk of developing the disease as well as those more likely to respond to preventative drug treatment.....
We have a diabetes watch blog as well and this is run by JoAnn. The latest post from this blog reads as follows: Very few women are ignorant of the advantages of breastfeeding their young ones, but the many benefits to the mother are often neglected or even unknown.....
"We're extremely encouraged by these results and the apparent cure seen in the mice treated with the active virus compared to untreated mice or those injected with inactivated virus," says Grant McFadden, a scientist at Robarts Research Institute in Ontario and a co-author of the study.
More than 130 days after the virus was injected into their tumors, more than 92 percent of the 13 mice were alive and apparently "cured," the study said.
"Those animals continued to show a selective and long-lived myxoma virus infection in the tumors themselves but that infection did not spread and harm the animal," study co-author Dr. Peter Forsyth, a professor in the departments of oncology, biochemistry and molecular biology at the University of Calgary, said.
"This and other factors suggest that myxoma virus warrants further investigation as a potential treatment for malignant brain tumors in people," Forsyth said.
These findings are published in the journal Cancer Research.
This option is very important as more and more women today are opting to have cosmetic breast implants. As women age, their risk of breast cancer increases, so a fraction of these women will eventually develop breast cancer. These are the patients who would be most interested in preserving their breasts and avoiding mastectomy.
"Past research was based on a small sample of patients and older radiation techniques," said Rosalyn Morrell, M.D., lead author of this Mayo Clinic study. "Therefore, we investigated a larger group of women treated with radiation using newer techniques that refuted the reports of poor cosmetic outcome among patients."
Between 1994 and 2004, researchers reviewed the records of 26 breast cancer patients with previously augmented breasts who were treated with breast conservation surgery and radiation at the Mayo Clinic. Eighty-five percent of patients followed over a three-year period had favorable cosmetic results following radiation therapy. None of the patients in the study suffered a relapse of their cancer.
The findings from the trial (NSABP-B31 trial) reports that patients who received combination of herceptin and chemotherapy had 4.1 percent chance of developing congestive heart failure compared to just 0.8 percent chance in those who use chemotherapy alone. The final analysis of data is still ongoing.
The NSABP-B31 trial analyzed 2,043 women with early stage breast cancer over-expressing Her2 with combination of chemotherapy with or without herceptin and found about 50 percent reduction in the recurrence rate of breast cancer in women who received herceptin.
The message is clear: herceptin in combination with chemotherapy is an excellent choice for the right patient, but if used in low risk patients the risk may outweigh the benefit.
Now there is a new use for this old drug: A recent study has demonstrated that Megace may combat the severe weight loss that can affect patients undergoing radiation treatment for cancer.
Weight loss can be a problem in patients undergoing radiation treatment for various types of cancers including lung cancer and cancers of the head and neck area. The high doses of radiation used to treat these cancers can cause decreased appetite and weight loss, nausea and painful swallowing. These patients typically receive radiation alone or a combination of radiation and chemotherapy, which can worsen the side effects of treatment, particularly nausea.
Researchers at Wake Forest University Baptist Medical Center who carried out a new study on this topic demonstrated that weight loss is a significant predictor of how well patients fare. Those who can eat adequate amounts and prevent weight loss often have a better chance of survival.
"The drug clearly reduced weight loss and improved quality of life in study patients," says Dr Michael Farmer, one of the study investigators. However, Dr Farmer also said: "While we know that weight loss is associated with a poorer outcome, we don't know for certain that preventing weight loss will improve survival."
Women with anal cancer, rectal cancer or cervical cancer were seen to have a higher risk. A fracture can lead to serious complications for elderly people.
Dr. Nancy Baxter of the University of Minnesota Cancer Center, the study's lead author of a recent study on this topic, said that, it is doubtful whether the findings would be applicable to younger women or to men, whose bones tend to be stronger than women's. The doctors must monitor bone density and treatment should be given to the women who received radiation therapy for pelvic cancer. This treatment should include calcium, medication and weight-bearing exercise.
It was found that the biggest risk was for those patients who had anal cancer due to the fact that their tumors generally perfuse to lymph nodes in the groin, where the hipbones are present and it is hard to withhold that part of the body from the radiation therapy.
These findings does not mean that radiation treatment should not be given to women with pelvic cancer because there is really no alternative for some of these cancers. Since late 1980's and 1990's there has been an improvement in radiation techniques and so now for the newly diagnosed patients the chances for damage may be lower.
For the first time, ultrasound is being used in animal models - to treat cancer by disrupting tumor blood vessels. Researchers at the University of Pennsylvania School of Medicine completed a study in mice in which they used ultrasound both to see a tumor's blood perfusion and then to treat it with a continuous wave of low-level ultrasound. After three minutes of treatment at an intensity similar to what is used in physiotherapy ultrasound (about 2.5 watts), researchers observed that the tumors had little or no blood supply.
"We used an ultrasound intensity higher than that used for imaging, but much lower than the high intensities used to ablate tissue. And we saw that this new use had a profound effect on shutting down the blood flow to the tumor and reducing the growth of the tumor in mice," said Chandra Sehgal, PhD, Director of Ultrasound Research in the Department of Radiology at Penn and the study's principal investigator.
"We wanted to study this use of ultrasound because we observed that some of these newly formed vessels created by tumors are very weak in nature, and if you turn on low-intensity ultrasound vibrations you can disrupt the blood flow through these vessels," explained Andrew Wood, DVSc, PhD, a co-investigator of the study and based in the University of Pennsylvania School of Veterinary Medicine.
Melatonin is a hormone naturally found in humans. Its association with cancer has been shown in many studies assessing links between shift work and cancer rates, and shown a consistent relationship. The association between melatonin levels and cancer progression has suggested to some that melatonin may be a modifier of cancer progression. In this latest study, researchers examined all clinical trials assessing the role of melatonin as a therapy for solid tumor cancers. They used a methodology called meta-analysis, a technique of analyzing multiple studies.
The authors reviewed 10 randomized clinical trials that included a total of 643 cancer patients with a variety of different solid tumor cancers. The types of cancers involved included lung, brain, skin, renal and breast cancer. "In this analysis, the effects appeared to be consistent across studies" say the authors. The researchers examined the effect of large doses of melatonin (10-40mg/day) on survival rates at one year. Melatonin reduced the risk of death at one year by 34%. "Effects this large certainly warrant further clinical trials" say the authors. The study also showed that melatonin was predominantly safe and had a beneficial effect on sleep patterns of patients.
By analyzing prostate samples from almost 19,000 men, which were collected as part of a seven-year prostate cancer prevention trial of almost 19,000 men in the United States shows that use of a drug called finasteride were 25 per cent less likely to develop prostate cancer.
"We think there are variants in that gene which may make men more susceptible to prostate cancer and we also think that there are variants in that gene that may make men more responsive or less responsive to finasteride," Prof Reichardt who is a Molecular biologist Juergen Reichardt, of the University of Sydney.
Finasteride inhibits testosterone from being converted into dihydrotestosterone. Prof Reichardt hopes the study will eventually lead to preventative strategies for men at highest risk of prostate cancer who would benefit the most from taking finasteride.
Fenasteride is available in Australia for treatment of hair loss in male.
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.
Medicineworld.org: Cancer blog
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