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Colon Cancer Blog: Use The New Test To Determine Camptosar Dose

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Dec 18, 2005

Use The New Test To Determine Camptosar Dose

Use The New Test To Determine Camptosar Dose
If you are receiving camptosar or planning for camptosar as a part of your colorectal cancer you can't afford to miss this information. A test to determine the dose of camptosar in the treatment of colorectal cancer is now available. Genzyme Corporation has announced the launch of the Invader® UGT1A1 Molecular Assay for colorectal cancer patients in the North America who are being considered for, or currently taking, the chemotherapy Camptosar (irinotecan). The test was recently cleared by the U.S. Food and Drug Administration (FDA) and was developed by Third Wave Technologies Inc.

The UGT1A1 Molecular Assay identifies patients who may be at increased risk for severe adverse reactions to Camptosar by detecting variations in the UGT1A1 gene that have been associated with that risk. A prospective clinical study indicated that patients with one of these variations have a greater than nine-fold risk of experiencing significant side effects from Camptosar than patients without it. Camptosar labeling was recently updated to include dosing recommendations based on a patient's UGT1A1 status.

"The UGT1A1 Molecular Invader Assay is a significant addition to Genzyme's oncology testing menu. We have initiated an education program aimed at physicians because it is critical that they are aware that this test will help them understand their patients' risk of serious side effects. This will help doctors treat their colorectal cancer patients with the appropriate dose of Camptosar," said Mara Aspinall, president of Genzyme Genetics, a business unit of Genzyme Corporation that focuses on the research and development of high quality, complex testing services.

The UGT1A1 test was 100 percent accurate compared to DNA sequencing, the standard for genotype determination.


Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer. publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.


Colorectal cancer
Colorectal cancer is a malignant tumor that arises from the inner wall of the large intestine or rectum. Colorectal cancer is the third commonest cancer diagnosed in the United States. Each year over 100,000 people are diagnosed with colorectal cancer in the United States. Most, of these cancers develop from growths in the colon called polyps. Removal of these polyps can prevent colon cancer.

Colon Cancer Blog: Use The New Test To Determine Camptosar Dose

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