MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Colon cancer blog: Pre-operative Chemo-radiation Prevents Local Relapse of Rectal Cancer

Colon cancer blog Colon cancer main Treatment of colon cancer  

Oct 15, 2005

Pre-operative Chemo-radiation Prevents Local Relapse of Rectal Cancer

Pre-operative Chemo-radiation Prevents Local Relapse of Rectal Canceriv chemotherapy Pre-operative combination of chemotherapy and radiation may improve outcomes in rectal cancer as per a recent study by German researchers. These researchers working with 26 different hospitals randomly assigned a total of 799 patients with clinical stage II or stage III rectal cancer to receive chemo-radiation either before or after surgery using the drug 5-FU.

Patients in the before-surgery group completed chemoradiation treatment six weeks before surgery. Those in the other group had surgery first, followed by the same chemoradiation regimen, except for a radiation boost delivered to the area where the tumor was removed. Afterwards, patients in both groups received additional treatment with 5-FU.

After a median follow-up period of just under four years, six percent of patients in the before-surgery group had had a local relapse, compared with 13 percent in the after-surgery group. Similar numbers of patients in both groups (36 percent for the before-surgery group; 38 percent for the after-surgery group) had a relapse elsewhere in the body.

Overall survival at five years was 76 percent for the before-surgery group and 74 percent for the after-surgery group. However, this difference was not statistically significant.

Overall, fewer patients in the before-surgery group suffered severe short-term or long-term side effects of treatment, such as diarrhea and the development of narrowings where the bowel was reconnected after removal of the tumor.

Some patients at the start of the trial had tumors that surgeons thought would require the complete removal of the rectum; this, in turn, would require a permanent colostomy (that is, creation of an opening in the wall of the abdomen to allow removal of waste from the body). Among these patients, the before-surgery group was more likely to avoid a colostomy - their rate of bowel reconnection after tumor removal was more than double that of the after-surgery group.

Sue      Return to Colon Cancer Blog Main


Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.

Janet      




Colorectal cancer
Colorectal cancer is a malignant tumor that arises from the inner wall of the large intestine or rectum. Colorectal cancer is the third commonest cancer diagnosed in the United States. Each year over 100,000 people are diagnosed with colorectal cancer in the United States. Most, of these cancers develop from growths in the colon called polyps. Removal of these polyps can prevent colon cancer.

Colon cancer blog: Pre-operative Chemo-radiation Prevents Local Relapse of Rectal Cancer

Cancer blog| Lung cancer blog| Prostate cancer blog| Adjuvant therapy| Colon cancer aasics| Colon cancer staging| Colon cancer support| Books| Diagnosis| Epidemiology| Genetic risk factors| Colon Cancer Main| Neoadjuvant| Risk factors| Statistics| Surgical treatment| Non metastatic| Causes| What is| Bevacizumab plus IFL| Colon cancer news| Oxaliplatin plus avastin| Colon cancer blog|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.