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Medicineworld.org: Pycnogenol improves memory in elderly

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Pycnogenol improves memory in elderly




New research accepted for publication in the Journal of Psychopharmacology, demonstrates Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, improves the memory of senior citizens.

The study results revealed Pycnogenol improved both numerical working memory as well as spatial working memory using a computerized testing system. The research was presented last week at the Oxygen Club of California 2008 World Congress on Oxidants and Antioxidants in Biology in Santa Barbara, CA.



Pycnogenol improves memory in elderly

These results support research from a range of disciplines that suggest that antioxidants may have an effect in preserving or enhancing specific mental functions, said Dr. Con Stough, lead researcher of the study. Cognitive research in this area specifically indicates that the putative benefits linked to antioxidant supplementation are linked to memory.

The double-blind, placebo controlled, matched pairs study, which was held at the Centre for Neuropsychology at Swinburne University, Melbourne Australia, examined the effects of Pycnogenol on a range of cognitive and biochemical measures in 101 senior individuals aged 60-85 years old. The study also examined the oxidative stress hypothesis of ageing and neurological degeneration as it relates to normal changes in cognition in elderly individuals. Participant screening for the study included medical history and cognitive assessment. Participants consumed a daily dose of 150mg of Pycnogenol for a three-month therapy period and were assessed at baseline then at one, two and three months of the therapy. The control and Pycnogenol groups were matched by age, sex, BMI, micronutrient intake and intelligence. The cognitive tasks comprised measures of attention, working memory, episodic memory and psycho-motor performance.

Blood samples were taken from subjects and after 3 months therapy a marker known as F2-isoprostanes significantly decreased with Pycnogenol, but not in the placebo group. F2-isoprostanes develop by oxidation of unsaturated fatty acids, which are present in especially high quantities in nerve cell membranes. The cooccurence rate of Pycnogenol significantly improving memory after three months and the oxidation of nerve membranes being significantly inhibited suggests that the antioxidant activity of Pycnogenol plays a major role for the clinical effects.

As per Dr. Stough, The antioxidant Pycnogenol had beneficial cognitive and biochemical effects for elderly individuals. Participants in the Pycnogenol groups showed improvement relative to the controls with the effects becoming evident from the second to third months of the Pycnogenol therapy.

Research on Pycnogenols cognitive function benefits are currently being investigated further. Several recent research studies on Pycnogenol studied the extracts effects on Attention Deficit Disorders including ADD and ADHD. Findings reported in the Journal of European Child & Adolescent Psychiatry showed Pycnogenol reduced ADHD symptoms such as hyperactivity and improved attention, concentration and motor-visual coordination in children with ADHD.


Posted by: Daniel    Source




Did you know?
New research accepted for publication in the Journal of Psychopharmacology, demonstrates Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, improves the memory of senior citizens. The study results revealed Pycnogenol improved both numerical working memory as well as spatial working memory using a computerized testing system. The research was presented last week at the Oxygen Club of California 2008 World Congress on Oxidants and Antioxidants in Biology in Santa Barbara, CA.

Medicineworld.org: Pycnogenol improves memory in elderly

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