MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Bronchial thermoplasty for severe asthma patients

Back to allergy news Blogs list Cancer blog  


Subscribe To Allergy News RSS Feed  RSS content feed What is RSS feed?

Bronchial thermoplasty for severe asthma patients

Bronchial thermoplasty for severe asthma patients
The Alair Bronchial Thermoplasty System from Asthmatx
Credit: Asthmatx
A medical device company that has developed a catheter-based procedure for the therapy of asthma, announced recently that positive results from the Research in Severe Asthma (RISA) Trial were reported today at the annual scientific assembly of the American Thoracic Society (ATS) by Neil Thomson, MD, Professor of Respiratory Medicine, University of Glasgow, Glasgow, Scotland. Clinically and statistically significant improvements in pulmonary function, asthma control, and quality of life, as well as a reduction in use of rescue medications, were observed following the bronchial thermoplasty procedure in patients with severe asthma. Bronchial Thermoplasty is an innovative non-drug therapy for asthma under clinical investigation in the United States.

The RISA Trial was conducted at a total of eight hospitals, in three countries, and reviewed the safety and efficacy of bronchial thermoplasty in 32 adult subjects with severe persistent asthma who remained symptomatic despite taking regular asthma medications. In comparison to patients who received only standard asthma medications, patients who received the bronchial thermoplasty procedure and standard medications showed clinically and statistically significant improvements in pulmonary function, quality of life, and asthma control, and used less rescue medicine nearly 6 months following the procedure. One year following the therapy, 50% of bronchial thermoplasty treated patients were able to wean completely off oral corticosteroids (OCS), in comparison to 14% of patients who did not receive the therapy. Further, a greater overall reduction in OCS dose was observed at 52 weeks in the bronchial thermoplasty treated patients compared with those that did not receive therapy at 52 weeks, eventhough this difference didnt reach statistical significance. The study was not powered to show statistical significance in medicine changes.

In this group of patients with severe asthma, an increase in respiratory-related symptoms, and hospitalizations correlation to these symptoms, were expected and observed during the period immediately following the procedure. These symptoms were of the type expected following bronchoscopy in patients with asthma, and they resolved on average within seven days.

"Following bronchial thermoplasty, patients with severe, refractory asthma demonstrated significant improvements in pulmonary function and asthma control," states Dr. Thomson. "These significant and seemingly long-lasting improvements came at the cost of a short-term increase in hospitalizations, but the apparent benefits seem to be greater than the manageable consequences of the procedure".

"The results from this randomized, controlled, multi-center trial provide some hope for patients with severe, refractory asthma people who despite taking state-of-the-art medications are still experiencing the disruptive and distressing symptoms of their asthma," states Glen French, CEO of Asthmatx, Inc. "We were especially encouraged by the data that suggested that patients may be able to reduce their oral steroid dose and still maintain their asthma control".


Posted by: JoAnn    Source




Did you know?
A medical device company that has developed a catheter-based procedure for the therapy of asthma, announced recently that positive results from the Research in Severe Asthma (RISA) Trial were reported today at the annual scientific assembly of the American Thoracic Society (ATS) by Neil Thomson, MD, Professor of Respiratory Medicine, University of Glasgow, Glasgow, Scotland. Clinically and statistically significant improvements in pulmonary function, asthma control, and quality of life, as well as a reduction in use of rescue medications, were observed following the bronchial thermoplasty procedure in patients with severe asthma. Bronchial Thermoplasty is an innovative non-drug therapy for asthma under clinical investigation in the United States.

Medicineworld.org: Bronchial thermoplasty for severe asthma patients

Asthma| Hypertension| Medicine| Allergy statistics| How to create a dust free bedroom|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.