From Medicineworld.org: Benign breast disease and breast cancer
Benign breast disease and breast cancer
Some of the benign breast lesions have been long recognized as risk factors for the development of breast cancer. Benign breast cancers have been incorporated into the Gale model of calculation of breast cancer risk. Now we have more evidence from a large study to have this conclusion.
Researchers noted that breast cancer developed in 707 patients of the total of 9087 women who have been diagnosed with benign breast disease. This represents 1.56-fold increase in the risk of development of breast cancer compared to the general population. The increased risk was noted for at least 25 years following biopsy for the benign breast disease. The following is the break down of increased risk in different sub groups of the study population.
Women who had no family history of breast cancer and had only non-proliferative benign breast lesions were not at increased risk of breast cancer. The breast cancer tend to occur in the same breast especially in women with history of atypia.
"Our findings indicate a link between select types of benign breast lesions and the later development of breast cancer," said Lynn Hartmann. "Women who have a breast biopsy that is benign must discuss the possibility of additional risks with their doctors," Hartmann said.
Antibody: A substance formed by the body cells that guard against invading organisms or substances. Example: It is rare for someone to get two attacks of chicken pox. With the first episode of chickenpox the body cells creates antibodies that defends the body against a second attack of chickenpox. See cancer terms for more cancer related terms.
Medicineworld.org: Benign breast disease and breast cancer
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