MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Avocados May Help Prevent Oral Cancer

Back to cancer blog Blogs list Cancer blog  


Subscribe To Cancer Blog RSS Feed  RSS content feed What is RSS feed?

Avocados May Help Prevent Oral Cancer




Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-malignant cells from developing into actual cancers, as per scientists at Ohio State University.

Scientists observed that extracts from Hass avocados kill or stop the growth of pre-malignant cells that lead to oral cancer. Hass avocados are year-round fruits known for their distinctive bumpy skin that turns from green to purplish-black as they ripen.

While there are more than 500 varieties of avocados grown worldwide, Hass avocados are the most readily available at supermarkets nationwide. Similar research has not been conducted on other varieties of avocados.


The findings are published online in the journal Seminars in Cancer Biology.




Lead author Steven M. D'Ambrosio, a member of the molecular carcinogenesis and chemoprevention program at Ohio State's Comprehensive Cancer Center, also wrote an accompanying editorial for the journal, discussing the cancer-fighting potential of fruits and vegetables. D'Ambrosio collaborated with Haiming Ding in Ohio State's College of Medicine.

Studies have long associated the consumption of fruits and vegetables with a reduced risk for various types of human cancer. The protective effect is attributed to the high levels of phytonutrients or phytochemicals - plant compounds thought to have health-protecting qualities - that are often found in dark colored fruits and vegetables.

"As far as we know, this is the first study of avocados and oral cancer," says D'Ambrosio. "We think these phytochemicals either stop the growth of premalignant cells in the body or they kill the premalignant cells without affecting normal cells. Our study focuses on oral cancer, but the findings might have implications for other types of cancer. These are preliminary findings, and more studies are needed."

D'Ambrosio, who collaborated with scientists in Ohio State's College of Pharmacy, observed that phytochemicals extracted from avocados target multiple signaling pathways and increase the amount of reactive oxygen within the cells, leading to cell death in pre-malignant cell lines. But the phytochemicals did not harm normal cells.

"These studies suggest that individual and a combination of phytochemicals from the avocado fruit may offer an advantageous dietary strategy in cancer prevention," says Ding, who is a member of the division of radiobiology, department of radiology.



Avocados are chock-full of beneficial antioxidants and phytonutrients, including vitamin C, folate, vitamin E, fiber and unsaturated fats. They are naturally sodium-free, contain no trans fats and are low in saturated fat, making them a healthy addition to any diet, D'Ambrosio says.

"The future is ripe for identifying fruits and vegetables and individual phytonutrients with cancer preventing activity," writes D'Ambrosio in the journal's editorial. "As we identify the molecular mechanisms and targets by which individual phytonutrients prevent cancer, we may be able to improve upon nature by formulating phytonutrient cocktails for specific cancers and individual susceptibility and risk."

Other Ohio State scientists involved in the study are Young-Won Chin in the College of Pharmacy and A. Douglas Kinghorn in the Comprehensive Cancer Center. The California Avocado Commission provided the Hass avocados for the research.




Posted by: Janet    Source




Did you know?
Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-malignant cells from developing into actual cancers, as per scientists at Ohio State University. Scientists observed that extracts from Hass avocados kill or stop the growth of pre-malignant cells that lead to oral cancer. Hass avocados are year-round fruits known for their distinctive bumpy skin that turns from green to purplish-black as they ripen.

Medicineworld.org: Avocados May Help Prevent Oral Cancer

Main Page| Cancer blog| Cancer blogs list| Lung cancer blog| Colon cancer blog| Prostate cancer blog| Breast cancer blog| Diabetes watch blog| Heart watch blog| Allergy blog| Bladder cancer blog| Cervical cancer blog| Colon cancer news blog| Diabetes news blog| Esophageal cancer blog| Gastric cancer blog| Health news blog| Heart news blog| Infectious disease blog| Kidney watch blog| Lung disease blog| Lung cancer news blog| Mesothelioma blog| Neurology blog| Breast cancer news blog| OBGYN blog| Ophthalmology blog| Ovarian cancer blog| Cancer news blog| Pancreas cancer blog| Pediatrics blog| Prostate cancer news blog| Psychology blog| Research blog| Rheumatology blog| Society news blog| Uterine cancer blog| Weight watch blog|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.