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Lung cancer blog: Nimotuzumab (TheraCIM) for treatment of lung cancer

Lung cancer blog Lung cancer main Non small cell  

Aug 17, 2005

Nimotuzumab (TheraCIM) for treatment of lung cancer

Nimotuzumab (TheraCIM) for treatment of lung cancer Few years ago there were very few treatment options available for lung cancer. Recent years have witnessed a dramatic increase in the selection of drugs that are effective against lung cancer. Some where during the last few years the mode of treatment for lung cancer have shifted from the traditional non-specific forms of chemotherapy to more specific targeted therapy. In the last few years we have seen FDA approvals for two targeted therapies for lung cancer namely Geftinib (Iressa) and Erlotinib (Tarceva).

More and more targeted therapies are in pipeline for lung cancer. It looks like the monstrous lung cancer is slowly getting defeated. Nimotuzumab (TheraCIM) is a monoclonal antibody directed against the EGF receptor (similar in action to Iressa). Nimotuzumab has demonstrated very encouraging results in both children and adults with brain cancer. Now YM BioSciences, manufacturer of Nimotuzumab, is proceeding to clinical trials in lung cancer using this new drug. The proposed randomized Non-Small-Cell Lung Cancer (NSCLC) trial will compare the effects of the combination of nimotuzumab with radiation against radiation alone in selected patients with stage IIB and III disease. This drug is also currently undergoing a Phase II monotherapy trial in Europe in patients with advanced metastatic pancreatic cancer." A recent study using nimotuzumab in combination with radiation therapy for nasopharyngeal cancer patients has completed in China and has demonstrated substantial benefit. Based on this finding nimotuzumab resulting in drug approved for sale in China.

Scott      Return to Lung Cancer Blog Main


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Lung cancer
We engage a never-ending daily struggle to understand and defeat the hidden mysteries of cancer. This is a long and laborious fight, but some moments stand out as grim reminders of the severity of the problem and ruthlessness of the enemy.

Lung cancer blog: Nimotuzumab (TheraCIM) for treatment of lung cancer

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