Your gateway to the world of medicine
Cancer News
About Us
Health Professionals
Patients and public
Contact Us

Lung cancer blog: Targretin may prolong survival in subgroup of patients with lung cancer

Lung cancer blog Lung cancer main Non small cell  

Aug 31, 2005

Targretin may prolong survival in subgroup of patients with lung cancer

Targretin may prolong survival in subgroup of patients with lung cancerTargretin® is a member of a subclass of retinoids that selectively activates retinoid X receptors. This drug is FDA approved for the treatment of lymphoma that affects the skin.

New research indicates that Targretin may be may be an effective drug in the fight against non-small cell lung cancer. In the recent meeting of the American Society of Oncology (ASCO), R. Govindan of Washington University Medical Center in St. Louis presented data showing the effectiveness of Targretin in the treatment of non-small cell lung cancer.

Results of the phase II trial of single-agent Targretin in patients with advanced non-small cell lung cancer, who had failed on previous chemotherapies, were treated with single agent targretin. This is the first study to evaluate the benefit of targretin as a single agent in the treatment of patients with non-small cell lung cancer.

At the time of presentation data from 146 were available and this showed a median survival of five months and overall one-year survival was 15 percent in previously treated patients with non-small cell lung cancer. The data was also analyzed to evaluate the survival of patients based on the triglyceride response to Targretin treatment. This was done because recently it was shown that high-grade triglycerided levels after treatment with targretin has been correlated with improved survival in patients with non-small cell lung cancer. With this sub analysis, two populations of patients were identified. Those with high triglyceridemia (grade 1 - 4) had a median survival of seven months and a projected one-year survival of 23%, compared with those with no hypertriglyceridemia who had a median survival of two months and a projected one-year survival of only 5%.

An inch forward in the treatment of lung cancer is good news, and this is especially true when the new advance may potentially improved survival in this sinister disease.

Scott      Return to Lung Cancer Blog Main

Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer. publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.


Lung cancer
We engage a never-ending daily struggle to understand and defeat the hidden mysteries of cancer. This is a long and laborious fight, but some moments stand out as grim reminders of the severity of the problem and ruthlessness of the enemy.

Lung cancer blog: Targretin may prolong survival in subgroup of patients with lung cancer

Comprehensive information on lung cancer| General information on lung cancer| Lung cancer information| Lung cancer blog| Non-small cell lung cancer| Small cell lung cancer| Chemotherapy of small cell lung cancer| Newer drugs in the treatment of small cell lung cancer| Prophylactic cranial irradiation| Treatment of extensive stage small cell lung cancer| Treatment of limited stage small cell lung cancer| Treatment of small cell lung cancer surgery| Epidemiology of lung cancer| Introduction to lung cancer| Prognostic factors in lung cancer| Risk factors for lung cancer| Screening and prevention of lung cancer| Signs and symptoms due to distant spread of lung cancer| Signs and symptoms of lung cancer| Staging of lung cancer|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.