Your gateway to the world of medicine
Cancer News
About Us
Health Professionals
Patients and public
Contact Us

Lung cancer blog: Cancer Vaccine Shows Promising Safety and Efficacy

Back to Lung cancer blog Lung cancer main Non small cell  

Sep 12, 2005

Lung Cancer Vaccine Shows Promising Safety and Efficacy

Cancer Vaccine Shows Promising Safety and EfficacyA few days ago, I wrote how I would like to see a vaccine for lung cancer, where you could vaccinate a smoker to prevent the occurrence of lung cancer, just like how you vaccinate a child against chicken pox.

Introgen Therapeutics, Inc. has a lung cancer vaccine in phase II clinical trials named as INGN 225. This is not a vaccine to prevent the occurrence of lung cancer in smokers, but is a treatment for patients who have been diagnosed with small cell lung cancer.

Interim results from an ongoing phase II clinical trial with this vaccine were recently presented at the 13th International Conference on Gene Therapy of Cancer. It showed that this vaccine is well tolerated and appears to sensitize lung tumors to additional chemotherapy, with 62 percent of patients who received second-line chemotherapy exhibiting objective responses. There were no appreciable INGN 225 related toxicities in any of the treated patients

INGN 225 is a personalized vaccine consisting of a cancer patient's dendritic cells, that utilizes the p53 tumor suppressor gene, to stimulate a cancer patient's immune system to destroy cancer cells.

"Historically, the expected objective response rate in patients with this type of advanced lung cancer is less than 25 percent," said Dmitry Gabrilovich, M.D., Ph.D., professor of oncology at the H. Lee Moffitt Cancer Center and co-principal investigator of the study. "The results of post- vaccination second-line chemotherapy are striking -- double what we would predict in this patient population. These data strongly suggest that INGN 225 sensitizes lung cancer cells to the effects of chemotherapy and may in fact significantly enhance the efficacy of subsequent chemotherapy."

All I have to say is every small step forward is an important step forward in the treatment of lung cancer.

Scott      Return to Lung Cancer Blog Main

Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer. publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.


Lung cancer
We engage a never-ending daily struggle to understand and defeat the hidden mysteries of cancer. This is a long and laborious fight, but some moments stand out as grim reminders of the severity of the problem and ruthlessness of the enemy.

Lung cancer blog: Cancer Vaccine Shows Promising Safety and Efficacy

Comprehensive information on lung cancer| General information on lung cancer| Lung cancer information| Lung cancer blog| Non-small cell lung cancer| Small cell lung cancer| Chemotherapy of small cell lung cancer| Newer drugs in the treatment of small cell lung cancer| Prophylactic cranial irradiation| Treatment of extensive stage small cell lung cancer| Treatment of limited stage small cell lung cancer| Treatment of small cell lung cancer surgery| Epidemiology of lung cancer| Introduction to lung cancer| Prognostic factors in lung cancer| Risk factors for lung cancer| Screening and prevention of lung cancer| Signs and symptoms due to distant spread of lung cancer| Signs and symptoms of lung cancer| Staging of lung cancer|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.