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Lung cancer blog: Eat vegetables to prevent lung cancer

Back to Lung cancer blog Lung cancer main Non small cell  

Sep 20, 2005

Eat vegetables to prevent lung cancer

Eat vegetables to prevent lung cancerEat lot of vegetables to prevent lung cancer! That may be a message from the recent study conducted by researchers at Georgetown University Medical Center and the Institute for Cancer Prevention. These researchers have found that a family of compounds found in cruciferous vegetables, such as broccoli, cauliflower, and watercress, blocked lung cancer progression in both animal studies and in tests with human lung cancer cells.
The results of the study were published in September 15 issue of Cancer Research.

Researchers studied isothiocyanates, a family of such compounds, to see if it has an impact on the stages of cancer development. To test that, the researchers induced lung tumor development in experimental mice by exposing them to tobacco carcinogens, and then they fed one group of mice the veggie compounds. They found that, the use of the chemicals resulted in a reduced development of benign lung tumors to malignant tumors.

Researchers however caution that it is difficult to draw any direct comparisons between human consumption of these vegetables and the effects seen in the mice studies.

In another study the researchers looked at the effect of the same compound on human lung cancer cells, which were forced to grow quickly (as cancer does) because of insertion of a gene known to be involved in cell growth and regulation. The laboratory test showed that the derivative of isothiocyanate caused death of these fast growing cells. This study provides some insight onto "one of the possible mechanisms of action" by which the compounds may offer some protection against lung cancer development, the researchers said.

The researchers hope that, these chemicals, if put into a veggie pill of sort, might some day be used to help current and former smokers ward off development of lung cancer.

Scott      Return to Lung Cancer Blog Main


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Lung cancer blog: Eat vegetables to prevent lung cancer

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