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Lung cancer blog: New clinical trial for small cell lung cancer

Back to Lung cancer blog Lung cancer main Non small cell  

Sep 22, 2005

New clinical trial for small cell lung cancer

New clinical trial for small cell lung cancer Vion pharmaceuticals, Inc recently announced opening of a phase II clinical trial using its anticancer agent Choretazine in small cell lung cancer. The study is open to patients with locally advanced or metastatic small cell lung cancer whose response to the initial treatment for the disease had been poor.

In small cell lung cancer, alkylating agents have demonstrated their activity and are frequently used after cisplatin-based combinations as second-line treatment. Studies have shown Choretazine, a novel alkylating agent has a broad-spectrum anti-tumor activity in preclinical studies. The safety profile, maximum tolerated dose and schedule for Choretazine in solid tumors have been investigated by two Phase I trials. This new Phase II study in small cell lung cancer is a multi-centered that looks forward to enroll up to nearly 90 patients.

Dr. Howard Burris, investigator at the Sarah Cannon Cancer Center in Nashville, Tennessee, commented, "We are excited to be offering this promising new therapy to our patients with small cell lung cancer. Innovative therapies are needed for this difficult-to-treat patient population."

Contact info: (203) 498-4210

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Lung cancer blog: New clinical trial for non-small cell lung cancer

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