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Lung cancer blog: The right chemotherapy radiation combination for non-small cell lung cancer

Lung cancer blog Lung cancer main Non small cell  

Sep 3, 2005

The right chemotherapy radiation combination for non-small cell lung cancer

The right chemotherapy radiation combination for non-small cell lung cancerOver the last decade, researchers have established that same time radiation therapy and chemotherapy is the optimal treatment strategy for patients with locally advanced lung caner (lung cancer that is advanced at it's original place with no spread to other organs). However the right combination and timing for this combined treatment is not clear yet.

A new study conducted by researchers from Jefferson Medical College adds to growing evidence that giving same time chemotherapy and radiation at the beginning of treatment improves survival in patients with locally advancer lung cancer.

These results appear September 1, issue of the Journal of Clinical Oncology (JCO)

In this multicenter, randomized phase 2 trial, researchers compared three different approaches. They divided more than 250 patients into three treatment arms. One group received chemotherapy before radiation. A second group had chemotherapy before and during radiation. Patients in the third arm received chemotherapy and radiation at the same time.

Dr. Curran and his colleagues found that the patients in the third arm did best, living several months more on average when compared against the standard treatment.

"That's in keeping with the observed results of other studies says Walter J. Curran Jr., M.D., professor and chair of radiation oncology at Jefferson Medical College at Thomas Jefferson University in Philadelphia and clinical director of Jefferson's Kimmel Cancer Center, who led the research. "Giving radiation and chemotherapy from day one appears to be the best approach for these patients," though side effects can at first appear to be worse.

Scott      Return to Lung Cancer Blog Main


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Lung cancer blog: The right chemotherapy radiation combination for non-small cell lung cancer

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