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Lung Cancer Blog: From Medicineworld.org

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Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
This page you have reached is an archive page of lung cancer blog. If you wish to read current posting of this blog, please go to lung cancer blog main page. If you wish to read the archived blog postings, simply scroll down to the lower part of the page.

Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      

Jan 16, 2006

Cadmium Lung Cancer Connection

Cadmium Lung Cancer Connection
Exposure to cadmium may occur in professions related to welding. The adverse health effects of cadmium are well established. It was suspected that workers who have been exposed to cadmium might have increased risk of developing lung cancer. Previously animal studies have shown a link between exposure to cadmium and development of cancer.

For the first time, now researchers have proved the first direct link between the build-up of industrial emissions of cadmium in the environment and lung cancer.

A Belgian study, published today on the Lancet website, is the first to link the accumulation of cadmium in the environment with higher rates of cancer.
The researchers followed nearly 1,000 people living in Northeast Belgium since 1985. Half lived in areas close to three zinc smelters where exposure was high while the others lived in low exposure areas. By June 2004 19 had died of lung cancer; 15 of them lived in the high exposure areas.

The Belgian study traced cadmium levels in the soils of the participant's gardens and measured their urine to calculate the build-up of cadmium in their bodies. The metal accumulates in the body over time, particularly in the kidneys.

The study, authored by Jan Staessen at the University of Leuven in Belgium, concluded: "We have shown a significant association between risk of lung cancer and environmental exposure to cadmium. To our knowledge, this is the first time such an association has been reported in an environmentally exposed population."

Scott      Permalink


Jan 12, 2006

Gamma Knife Surgery Improves Survival

Gamma Knife Surgery Improves Survival
Gamma knife, or radio-surgery is a method of treating brain tumors with focused radiation beams. Until now it was considered a palliative treatment meaning that is was only thought to improve symptoms. Now there is evidence to suggest that many patients can survive for years after undergoing effective gamma knife radio-surgery for cancers that have spread to the brain.

Radio-surgery is shown to be capable of extending survival by 13 months or longer, depending on the tumor type. These conclusions come from a recent research conducted by Dr. Douglas Kondziolka and colleagues from the University of Pittsburgh Medical Center, Pennsylvania. The study included 44 patients who survived more than four years after undergoing radiosurgery to determine clinical and treatment patterns that affect the outcome. These patients who have undergone gamma knife surgery had an average life span of 68 months with some patients living as long as 156 months so far.

Researchers have found those patients who survived more than four years after radio-surgery had higher pre-treatment scores on physical functioning and had fewer metastases, and less cancer in other parts of the body than those patients who died soon after radio-surgery.

Sherin      Permalink


Jan 9, 2006

Jury Rules Asbestos Link From Welding Rods To Mesothelioma

Jury Rules Asbestos Link From Welding Rods To Mesothelioma Digital Rectal Examination
This case has been pending in New York State appeals court for some time, but on Dec. 29th in a first-ever jury finding that asbestos-containing welding rods, sold in the billions up to the early 1980's, had caused lung cancer and mesothelioma. Attorney Jerome H. Block of the nationally known mass toxic tort law firm of Levy Phillips and Konigsberg has recently made this announcement.

This New York Supreme Court, Appellate Division, First, upheld the July 2003 jury verdict in favor of, Angel Gomez, who died following the trial, and the late Daniel Tucker. Both men worked with and around asbestos-containing welding rods. The jury awarded Gomez a total of approximately $3.19 million against Lincoln Electric Company. Jury however, reduced 25 percent of the compensation percent since Gomez was a cigarette smoker. Tucker's estate was awarded a total of approximately $3.5 million split between Lincoln and Hobart Brothers Company.

The welding rods at issue in the Gomez and Tucker cases continue to be a top-selling, all-purpose welding rod. Up to the early 1980s, these rods were coated with a mixture containing 5% to 15% asbestos, according to trial testimony.

Scott      Permalink


Jan 6, 2006

Lou Rawls Dies Of Lung Cancer

Lou Rawls Dies Of Lung Cancer
On December 18. 2005, I wrote about Lou Rawls, and his fight against lung cancer. Today I am writing about the sad demise of this gifted singer to lung cancer.

Lou Rawls was diagnosed with lung cancer just over a year ago. He was found to have spread of lung cancer to his brain in May 2005. In December, when I was writing that blog post, Lou Rawls was still bravely fighting his lung cancer.

Rawls is an accomplished artist and has released more than 70 albums, he has been in movies, television shows and voiced-over many cartoons. His career covered almost every form of black American music from gospel and blues to RandB, soul and jazz. He was 70 years old when he finally succumbed to lung cancer. Rawls won three Grammy awards and 13 nominations in a career that lasted more than 40 years

Rawls died at Cedars-Sinai Medical Center, as per reports where he was receiving his medical treatment.

Rawls received many honors during his lifetime including having a street named after him in Chicago. Rawls recently filmed public service announcements for Hurricane Katrina relief. His last public performances were a series of three concerts he gave in San Diego in mid-November.

In 1958, while touring the South with the Travelers and Sam Cooke, Rawls was in a serious car crash, which claimed the life of one person. Rawls was actually pronounced dead before getting to the hospital where he stayed in a coma for 5 1/2 days. It took him months to regain his memory and a year to fully recuperate. Rawls considered the event life changing.

Again this is a grim reminder for all of us regarding the dangers of lung cancer and smoking.

Scott      Permalink


Jan 4, 2006

New Clinical Trial For Patients With NSCLC

New Clinical Trial For Patients With NSCLC

SNS-595 is the lead anti-cancer therapeutic drug for Sunesis Pharmaceuticals, Inc. The company has announced today that, that patient treatment has commenced in a Phase II clinical trial using this drug. This trial, which is now open to enrolment, is an open-label, multi-center study with idea of examining the safety and efficacy of SNS-595 as a second-line agent in patients with non-small cell lung cancer who have failed first-line platinum-based therapy.

This SNS-595 an apoptosis inducing drug and is claimed to be the first in this group. Patients with non-small cell lung cancer who have failed first-line treatment will be enrolled at multiple centers in the United States. Eligible patients will receive SNS-595 every three weeks at the maximum tolerated dose for heavily pre-treated patients identified in Phase I.

Scott      Permalink


Jan 1, 2006

Smokers with Family history of Lung cancer should be Screened

Smokers with Family history of Lung cancer should be Screened
Researchers are urging current and former smokers who have a strong family history of lung cancer to take a lung function test and undergo screening with spiral computed tomography (spiral CT scan). If the relative was diagnosed prior to age 50 special attention has to be given to screening.

These recommendations appear in an article on familial lung cancer in the recent issue American Journal of Respiratory and Critical Care Medicine.

These authors emphasized that 85 to 95 percent of all lung cancers are attributable to cigarette smoking. The rate of lung cancer in the U.S. has dropped over the past two decades as a result of extraordinary personal and public health smoking cessation efforts. Yet, an estimated 46 million former smokers in America remain at risk for the disease, along with almost 49 million who continue to smoke. Consequently, further efforts need to be made to identify high-risk populations.

"Because cigarette smoking is such an overwhelming risk factor and preventable, the importance of family history and genetic susceptibility to lung cancer risk has been overlooked," said Dr. Schwartz.

She pointed out that individuals with a family history of lung cancer are at approximately a two- to threefold increased risk of developing the illness.

In one screening study, at least one first-degree relative had lung cancer in almost 14 percent of the 26,000 patients diagnosed with the disease.

Scott      Permalink


Dec 31, 2005

Beware of Sharks!

Beware of Sharks!
As caner strikes some person, it not only exhausts the person physically and emotionally but also can also affect the person and family financially. Naturally every one of us wants to get the best price for the drugs in the market. While you can research on the Internet and often get very good deals for many of the cancer medications, you should be very careful with this process. There are sharks out there waiting for the right opportunity.

Go to http://www.cancercure.org/ and you can see a list of cancer medications that you can buy from this site. Also you can buy many medications and alternative therapies that can cure your cancer. They offer you FDA approved treatment of cancer that will keep you cancer free for the rest of your life.

This and a series of other pharmaceutical websites are run by a man once known in South Florida as "Big Pimpin' Pappy" who has now moved into the bogus pharmaceutical business using a Boca Raton post office box.

Arthur Vanmoor was deported to the Netherlands after pleading no contest last year to conspiracy and racketeering charges for allegedly running a lucrative and organized prostitution ring in Broward and southern Palm Beach counties.

A federal judge ordered http://www.cancercure.org/ to be shut down immediately, but it is still operational at the time of posting this blog.

Janet      Permalink


Dec 26, 2005

Black Smokers More Susceptible to Lung Cancer

Black Smokers More Susceptible to Lung Cancer
There are inherent difference between African Americans and Caucasians when it comes to risk factors for lung cancer. A positive family history of lung cancer may be more significant for African Americans than Caucasians.

This is based on a recently published research data from Wayne State University. Detroit researchers found that having a parent, grandparent or sibling with lung cancer before the age of 50 poses a higher risk for African Americans than Caucasians.

Researchers evaluated more than 7,500 first-degree relatives of 700 people who developed lung cancer at an early age. They compared them with a cancer-free control group.

By age 70, 25 percent of African Americans who were smokers and had a close relative with lung cancer developed cancer versus only 17 percent of white.

African Americans with a family history of lung cancer were twice as likely to develop lung cancer as Caucasians, after factoring in other risk factors.

Scott      Permalink


Dec 25, 2005

Merry Christmas From Medicineworld.org

Merry Christmas From Medicineworld.org
Medicineworld wishes all our readers merry Christmas.

Oh, jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh
Jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh

A day or two ago
I thought I'd take a ride
And soon Miss Fanny Bright
Was seated by my side
The horse was lean and lank
Misfortune seemed his lot
We got into a drifted bank
And then we got upsot

Oh, jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh
Jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh yeah

Janet      Permalink


Dec 25, 2005

Do You Read All Of Our Medical Blogs?

Do You Read All Of Our Medical Blogs?
Do you read all of the medical blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on various medical topics. Medicieworld.org is publishing a wide variety of blogs on different topics.

Breast cancer blog: Breast cancer blog is run by Janet and colleagues. Latest post from this breast cancer blog reads as follows: Location of Breast Cancer Does Matter - Does it really matter which part of the breast you develop cancer? Researchers say yes.
Researchers from Switzerland recently reported that women with early breast cancer in the lower inner quadrant (the lower part of the breast, closer to the center of the body) are twice as likely to die of their cancer as women with cancer diagnosed in other parts of the breast. Researchers speculate this could be due to undetected spread of the cancer to the lymph nodes of the internal mammary chain (lymph nodes near the center of the chest). These lymph nodes are difficult to be evaluated for the presence of cancer.......

Lung cancer blog: Lung cancer blog is run by Scott and colleagues. Latest post from this lung cancer blog reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute.......

Colon cancer blog: Colon cancer blog is run by Sue and colleagues. Latest post from this cancer blog post reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute...............

Prostate cancer blog: Prostate cancer blog is run by Mark and colleagues. Latest post from this prostate cancer blog reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute...............

We have a diabetes watch blog as well and this is run by JoAnn and colleagues. The latest post from this diabetes watch blog reads as follows: Health Canada Issues Warning For Avandia and Avandamet - Health Canada is issuing warnings for two commonly used drugs to treat Type-2 diabetes. The warning states that use of these drugs may lead to new cases or worsening of a vision problem called macular edema.......

Heart watch blog: Heart watch blog is run by Daniel and colleagues. The latest post from this heart watch blog reads as follows: Fish Oil Combats Heart Problem Related To Pollution - You probably can't do much to improve the air pollution around you, but now you can protect yourself from some of the harmful effects of air pollution on the heart. A new research finding suggests that daily supplementation with omega-3 fatty acid (fish oil) prevents a potentially-deadly decline in heart rate variability (HRV) associated with exposure to indoor air pollution, researchers from the US and Canada report......

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. The latest post from this cancer blog reads as follows: Pancreatic Cancer: Looking Forward To Skin Rash! - Probably you all know that a new drug combination Tarceva and Gemzar has been FDA approved recently for the treatment of pancreatic cancer. Did you know that, if you are developing a bad skin rash while on this treatment it is a good sign! I am not kidding, the study that led to the approval of this combination was presented in the American Society of Clinical Oncology meeting in 2005. This study has shown that the combination of Tarceva and Gemzar works best in patients who had a bad skin rash!......

Scott      Permalink


Dec 23, 2005

Cancer Death Rate Continues to Drop in U.S.

Cancer Death Rate Continues to Drop in U.S.
It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute.

The stabilization of the cancer diagnosis rate shows that Americans are taking some steps to help prevent cancer, the agency said, and the use of some screening tests is at high rates in an effort to detect cancers early.

"The overall message of the report remains positive," NCI Director Andrew C. von Eschenbach said in releasing the report. "The evidence that I have seen convinces me that we are poised to make dramatic gains against cancer in the near future."

The rate of new cases of cancer was 488.6 per 100,000 Americans in 2002, close to the rate of 488.1 a year earlier.

At the same time, the death rate for all cancers was 193.6 per 100,000, down from 195.7 a year earlier and continuing a steady downward trend. Death rates for prostate cancer showed, 28.0 per 100,000, down from 28.9, breast cancer death rates were down to 25.4, from 26.0, colorectal cancers were down to, 19.6, from 20.1 and lung death rates were down to 54.8 from 55.2.

Smoking by youths, which had been growing in the 1990s, has been declining since 1997, the report said. Youths are starting to smoke later, with average age for first use of cigarettes at 15.4 in 2003, up from 14.9 a decade earlier. And the percentage of high schoolers who smoked cigarettes fell from 30.5 percent to 21.9 percent in the same period.

Janet      Permalink


Dec 21, 2005

Chest X-Rays Can Identify Early Lung Cancer

Chest X-Rays Can Identify Early Lung Cancer
Screening chest x-ray identifies a considerable number of lung cancers at an early potentially curable period, according to early findings from the leading US study of the efficacy of screening for lung cancer in men and women.

As per the early chest x-rays of 77,465 people in the screening section of the test, 5,991 -- nearly 9 percent -- had results that were considered "suspicious for lung cancer."

Upon advanced testing, 126 persons were detected with lung cancer, say the investigators, 44 percent of the tumors were early stage I cancers.

Prominently, 44 percent of the cancers were in the disease's initial stage, noted lead researcher Dr. Martin Oken of Minnesota's Hubert H. Humphrey Cancer Center.


He pointed out that screening is beneficial on the supposition that it can lead to detection of dangerous lung cancers at an earlier, more localized phase when it is more likely to be curable. In the present study, nearly 50 percent of screening-detected lung cancers were localized."

Lung cancer may not produce any symptoms at the initial period of growth. When a patient starts to experience symptoms, such as a cough that doesn't go away, the cancer is often highly developed and cure is rarely possible.

Many scientists are betting that tests like, spiral CT scan, would prove a better screening tool. A separate government study is under way comparing X-rays with spiral CTs. This $300 test is already is in high demand, as many smokers and former smokers aren't waiting for the evidence from clinical trials.

Scott      Permalink


Dec 20, 2005

Phyllis Gretzky Dies From Lung Cancer

Phyllis Gretzky Dies From Lung Cancer
Phyllis Gretzky, the mother of Canadian hockey icon Wayne Gretzky, passed away Monday night from lung cancer, as per reports. She was 64 years old.

Phyllis Gretzky had battled lung cancer since the fall of 2004. Wayne Gretzky took a leave of absence from coaching the Coyotes Saturday night to return home to Brantford, Ontario, to spend time with his ailing mother.

Her husband Walter, who is popular throughout Canada as a goodwill hockey ambassador, survives Phyllis Gretzky.

Her children include first-born Wayne, daughter Kim and other sons Keith, Glen and Brent.

Gretzky, the leading scorer in National Hockey League history, took over as Phoenix's coach in August five years after buying a stake in the team. The Coyotes have a 16-15-2 record this season and are in fourth place in the five-team Pacific Division.

The Coyotes said it's not known when Gretzky would return to the team. He was the eldest of Phyllis Gretzky's five children.

Scott      Permalink


Dec 18, 2005

Rawls Fighting Lung Cancer

Rawls Fighting Lung Cancer
Famous singer Lou Rawls is being treated for lung cancer, and his estranged wife said that his cancer has spread to the brain.

"Don't count me out, brother," Rawls said late last week from his room at Cedars-Sinai Medical Center.

The lung cancer was diagnosed a year ago and the brain cancer in May, his estranged wife, Nina, said during a marriage annulment hearing Thursday in Arizona.

Rawls has released more than 70 albums, been in movies, television shows and voiced-over many cartoons.

A high school classmate of soul giant Sam Cooke, Rawls sang with Cooke in the Teenage Kings of Harmony, a 50's gospel group. Rawls enlisted in the US Army as a paratrooper in the 82nd Airborne Division in 1955. He would leave the "All-Americans" three years later as a Sergeant and hook up with a group he had sang with before enlisting, the Pilgrim Travelers. In 1958, while touring the South with the Travelers and Sam Cooke, Rawls was in a serious car crash which claimed the life of one person. Rawls was actually pronounced dead before getting to the hospital where he stayed in a coma for 5 1/2 days. It took him months to regain his memory and a year to fully recuperate. Rawls considered the event life-changing.

Rawls, 70, is trying to annul his two-year marriage and protect hundreds of thousands of dollars of assets his wife "absconded with." She says she transferred nearly $350,000 to prevent one of Rawls' two adult daughters from seizing it.


Scott      Permalink


Dec 16, 2005

Cure Cancer With Your Personal Computer

Cure Cancer With Your Personal Computer
I was reading this report from ABC and thought that this story is worth mentioning here. The report says that you can contribute towards cancer research by allowing the supercomputer of the researchers to use some of the computing powers of your home pc.

The idea is this: you can download a small program and install it on your computer and then forget about it. The researchers would use that extra computing power on your computer, to expand the capabilities of their super computer.

The report says that, modern computers are incredibly powerful machines whose processing abilities are seldom used to their full abilities. Regardless of how hard you push it, you're probably not using as much of the computer's power as you think.

Is it safe, that's the next question?
With widespread reports of Internet virus attacks, worms, Trojan horses, spyware and identity theft, some might fear that participating in a grid will make them more vulnerable to becoming a virtual victim.

"We are comfortable saying that on any computer you're willing to browse, you should be comfortable putting our client on," said Armentrout of his company's grid software. "We say it's safer than surfing."

Litow said that IBM is also committed to keeping participants safe, and that in the year IBM's World Community Grid has been in existence - a network of humanitarian grid projects - there hasn't been a single problem.

You may read the whole story here

Janet      Permalink


Dec 15, 2005

Hormonal Therapy For Lung Cancer?

Hormonal Therapy For Lung Cancer?
(Image courtesy of University of Alabama at Birmingham). It is already known that, much like breast tumors, some lung tumors require estrogen to grow. Now a medical student conducting research on a Howard Hughes Medical Institute and colleagues have managed to stop the growth of human lung cancer cells in mice with a class of breast cancer drugs called aromatase inhibitors. Her findings are reported in recent issue of the journal Cancer Research.

"It was a natural progression of the work that had already been done linking estrogen and lung cancer," said Olga Weinberg, who delayed her fourth year at Vanderbilt University School of Medicine to work on the project.

"We followed one of the clues as to why this is happening, namely that estrogen drives the growth of certain types of lung cancer in women." said senior author Richard Pietras, Weinberg's research mentor at the University of California at Los Angeles.

"The production of estrogen takes several steps, and aromatase is the key to the process," said Weinberg. "Without aromatase, you don't get estrogen."

To confirm that lung cancer needs aromatase, the team first searched for the enzyme in laboratory-grown lung cancer cells. After finding it there, they also searched 53 non-small cell lung tumor samples from patients Using an antibody specific for aromatase and immunohistochemistry techniques, they found that 88 percent of the specimens from women and 86 percent from men contained high levels of the enzyme.


"Once we saw that aromatase was active, we wanted to see if we could inhibit it with the same drugs they use for breast cancer," said Weinberg. The team treated their cells with the drug anastrozole for 48 hours, finding that it did in fact shut down aromatase activity and retard tumor growth in the lab.

"We found that tumors with both high and low levels of aromatase were sensitive to the drug," said Pietras.

Finally, the team grafted human lung tumors onto mice. One group of mice received anastrozole for 21 days, while a second group did not. The tumors in the mice taking the drug grew 90 percent slower than the tumors in the untreated mice.

Scott      Permalink


Dec 14, 2005

Lung Cancer Trials Biased Against Blacks and Women

Lung Cancer Trials Biased Against Blacks and Women
Race and gender affect enrollment in lung cancer clinical trials in the United States, according to a study that found that women and blacks were least likely to take part in such trials.

The Wayne State University study of 427 lung cancer patients in Detroit also identified a need to improve educational and outreach programs to attract a wider range of patients to treatment trials for lung cancer.

The researchers reviewed data from 175 black lung cancer patients and 252 lung cancer patients from other races who were eligible for clinical trials at the Karmanos Cancer Institute between 1994 and 1998. Of this group, 91 patients (21 percent) took part in a lung cancer treatment trial.

Patients who did not take part in any trial were more likely to be black (45 percent versus 25 percent of enrollees), female (43 percent versus 32 percent of enrollees), and over age 70 (24 percent versus 10 percent of enrollees).

The findings appear in the Jan. 15, 2006 issue of the journal Cancer.

The study focused on enrollment at a single medical center and did not examine other factors that could influence clinical trial participation, so the findings should be viewed with caution, the researchers note. Those other factors include religious beliefs, lack of trust in the medical establishment, and lack of knowledge about clinical trials.

"New recruitment strategies targeting specific patient subgroups might be helpful in ensuring equal representation of women and minority groups in cancer clinical trials," the study authors conclude.

Scott      Permalink


Dec 11, 2005

New Lung Cancer Drug

New Lung Cancer Drug
Novelos Therapeutics Inc. has recently announced that its lead chemotherapy drug to treat non-small cell lung cancer had gained FDA approval to advance into late-stage, or phase III, clinical testing.

The drug trial will test the drug, designated NOV-002, in combination with currently used chemotherapy to treat patients with advanced non-small-cell lung cancer who have not undergone any previous treatment. The company hopes to begin enrolling patients in the phase III study by the third quarter of 2006.

Novelos Therapeutics, Inc., is a Boston-based biotechnology company focused on the development of therapeutics to treat cancer and hepatitis. Today's announcement marks the first time the company has been given FDA approval for a large clinical trial that often forms the final testing in humans before submission to the FDA for approval to sell the drug.

NOV-002, is approved and marketed in the Russian Federation by Pharma BAM under the trade name Glutoxim. It has been administered to over 5,000 patients, and been found to be effective and safe.

The drug is designed to provide patients with protection from highly toxic chemotherapy agents, and to enhance the body's immune response to cancer. The result is that patients are better able to tolerate chemotherapy allowing them to undergo more treatment cycles.

Determining whether that translates into longer survival will be the research objective of the phase III trial. Novelos will seek approval of the final study design under a FDA's Special Protocol Assessment (SPA) during the first half of 2006.

Scott      Permalink



Lung cancer
We engage a never-ending daily struggle to understand and defeat the hidden mysteries of cancer. This is a long and laborious fight, but some moments stand out as grim reminders of the severity of the problem and ruthlessness of the enemy. We recently heard about the sad demise of Peter Jennings, who was the news anchor of ABC News for a long time.

Lung Cancer Blog: From Medicineworld.org

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