MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Prostate Cancer Blog: PSA Test Affected By Demographic And Lifestyle Factors

Return to Prostate Cancer Blog Main Cancer Blog List Of Blogs  

Dec 12, 2005

PSA Test Affected By Demographic And Lifestyle Factors

PSA Test Affected By Demographic And Lifestyle Factors
According to a new study published in latest issue of journal Cancer, the reliability of a prostate cancer-screening test may be compromised by lifestyle and demographic factors. The study reveals that the rate of change in the level of prostate specific antigen (PSA) over time called PSA velocity can be significantly affected by age, race, and diet. This may lead to falsely lower or elevated values and possible misinterpretation by doctors. Single determinations of PSA level, which is the most common use of the PSA screening test, were also affected by age and body mass index (BMI).

Studies have shown a decrease in prostate cancer mortality since 1992 and some researchers attribute a portion of that fall to the widespread adoption of the PSA test. But some experts say that measuring PSA levels alone causes too many false positives and leads to many unnecessary tests, such as biopsies and transrectal ultrasounds.

Investigators continue to refine the test, including developing calculations such as PSA velocity, PSA density, and age-specific PSA, or other tests such as percent free PSA. However, there is poor understanding of the effect of other factors, such as diet, race, and weight on PSA and its related measurements.

Alan R. Kristal, Dr.P.H. of the Fred Hutchinson Cancer Research Center in Seattle and colleagues reviewed PSA and PSA velocity data from 3,341 cancer-free men to determine relationships between PSA tests and demographic and lifestyle factors.

PSA velocity was significantly affected by age, race and diet, potentially affecting its clinical interpretation. PSA velocity decreased as men aged, and increased with higher total energy calorie diets. PSA velocity in African Americans was on average almost twice the level of Caucasians, and was lower among users of high-dose calcium supplements. Large weight fluctuations also affected PSA velocity. Men who gained weight had lower PSA velocity and those who lost weight had higher PSA velocity.

Mark      


Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      


Prostate cancer
The prostate is located just below the bladder and in front of the rectum in male. The tube that carries urine runs through the prostate. The prostate contains cells that make some of the seminal fluid. This fluid protects and nourishes the sperm. Prostate cancer usually starts in the gland cells of the prostate. This kind of cancer is known as adenocarcinoma. Prostate cancer is usually a slow disease, but sometimes it can grow fast and spread quickly to other organs.

Prostate Cancer Blog: PSA Test Affected By Demographic And Lifestyle Factors

Cancer blog| Lung cancer blog| Colon cancer blog| Prostate cancer news| Can you prevent prostate cancer?| Case studies in prostate cancer| Prostate cancer main| Introduction to prostate cancer| Summary of prostate cancer| Who is at risk of prostate cancer?| Prostate cancer blog|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.