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Prostate cancer blog: What Predicts Prognosis In Prostate Cancer

Prostate cancer blog Prostate cancer main Prostate cancer news  

Nov 13, 2005

What Predicts Prognosis In Prostate Cancer

What Predicts Prognosis In Prostate Cancer
Time required for doubling of the PSA value (PSA doubling time) may be a better predictor of prognosis in prostate cancer, than the rate at which the PSA increases (PSA Velocity) as per researchers at the Mayo Clinic in Rochester, Minnesota. These researchers reviewed the records of 2,290 patients with multiple preoperative prostate specific antigen (PSA) measurements, recording PSA velocity, and the rate at which PSA levels doubled (PSA doubling time). They found that while PSA velocity (PSAV) is simpler to calculate, PSA doubling time (PSADT) might be a better indicator of untreated prostate cancer.

As both measurements proved valuable, looking at the speed at which PSA increases may be more important than simply recording PSA levels, allowing better prediction of disease progression and likelihood of death after radical prostatectomy surgery.

"The level of PSA in the blood has less prognostic value than we previously thought, and we don't have another serum marker to help us," said Dr Michael Blute, Mayo Clinic urologist and lead investigator of the study. "It was important for us to find other ways to look at PSA data and translate that into information that will save lives, and I believe we have done that."

Mark      Return to Prostate Cancer Blog Main


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Janet      




Prostate cancer
The prostate gland is located just below the bladder and in front of the rectum in male. The tube that carries urine runs through the prostate. The prostate contains cells that make some of the seminal fluid. This fluid protects and nourishes the sperm. Prostate cancer usually starts in the gland cells of the prostate. This kind of cancer is known as adenocarcinoma. Prostate cancer is usually a slow disease, but sometimes it can grow fast and spread quickly to other organs.

Prostate cancer blog: What Predicts Prognosis In Prostate Cancer

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