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Prostate cancer blog: Hormone therapy improves survival in localized prostate cancer

Prostate cancer main Prostate cancer news Prostate cancer basics  

Oct 6, 2005

Hormone therapy improves survival in localized prostate cancer

Hormone therapy improves survival in localized prostate cancerPatients who have advanced prostate cancer confined to the prostate, radiation treatment in combination with a six-months of hormonal treatment can improve survival by as much as 50 percent, as per the new research results.

Although hormone therapy is now standard treatment for metastatic prostate cancer, whether it is beneficial in treating prostate cancer still confined to the organ has been less clear. Also it was not clear if a short-term hormone therapy might be effective in this setting since, most patients now receive the treatment over a period of at least three years.

"Finding that we can stop cancerous progression in 40 percent of men by just six months of testosterone suppression treatment with minimal side effects is enormously important," said study author Dr. Jim Denham, from the Trans-Tasman Radiation Oncology Group and University of Newcastle, New South Wales, Australia.

In their study, Denham's team randomly assigned 818 men with locally advanced prostate cancer to radiation treatment with no testosterone suppression, or three months or six months of testosterone suppression.

Reporting the recent online edition of The Lancet Oncology, the Australian team found that men treated with three months of hormone therapy before and during radiation were at a 35 percent lower risk of relapse compared to men receiving radiation alone. For men treated with six months of hormone therapy before and during radiation, that risk of relapse was reduced by 44 percent.

In addition, survival among men receiving both radiation and hormone treatment was 54 percent better compared with men who received radiation alone, according to the report.

Mark      Return to Prostate Cancer Blog Main

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Prostate cancer
The prostate gland is located just below the bladder and in front of the rectum in male. The tube that carries urine runs through the prostate. The prostate contains cells that make some of the seminal fluid. This fluid protects and nourishes the sperm. Prostate cancer usually starts in the gland cells of the prostate. This kind of cancer is known as adenocarcinoma. Prostate cancer is usually a slow disease, but sometimes it can grow fast and spread quickly to other organs.

Prostate cancer blog: Hormone therapy improves survival in localized prostate cancer

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