http://medicineworld.org/news/ovariannews.html MedicineWorld.Org brings daily ovarian cancer news from various sources to keep you updated on the latest events in the world on this topic. Medicineworld heart watch news service is the most comprehensive heart watch news service on the internet. We keep an archive of previous few days of news on this site. Please go down through the list to find the older news items. Fri, 18 Apr 2008 02:09:07 GMT en-us http://medicineworld.org/images/ovaries.jpg http://medicineworld.org/news/ovariannews.html 108 87 http://medicineworld.org/cancer/lead/4-2008/ovarian-cancer-stem-cells-identified.html http://medicineworld.org/cancer/lead/4-2008/ovarian-cancer-stem-cells-identified.html Fri, 18 Apr 2008 02:09:07 GMT Scientists at Yale School of Medicine have identified, characterized and cloned ovary cancer stem cells and have shown that these stem cells may be the source of ovary cancers recurrence and its resistance to chemotherapy. These results bring us closer to more effective and targeted therapy for epithelial ovary cancer, one of the most lethal forms of cancer, said Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine........ ]]> http://medicineworld.org/cancer/lead/4-2008/death-of-ovarian-cancer-cells.html http://medicineworld.org/cancer/lead/4-2008/death-of-ovarian-cancer-cells.html Fri, 18 Apr 2008 02:09:07 GMT In a discovery that may be useful for maintaining remission in chemo-resistant ovary cancer, Yale researchers report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovary cancer cells by halting the activation of a protein pathway called mTOR. Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine, and associate research scientist Ayesha Alvero, M.D. presented the data April 15 during an oral presentation at the annual meeting of the American Association for Cancer Research........ ]]> http://medicineworld.org/cancer/lead/3-2008/ovary-less-responsive-to-chemo.html http://medicineworld.org/cancer/lead/3-2008/ovary-less-responsive-to-chemo.html Fri, 18 Apr 2008 02:09:07 GMT Recurrent low-grade serous carcinoma, a rare type of ovary cancer, is less sensitive to chemotherapy and therefore more difficult to treat than more common high-grade ovary cancers, as per scientists from The University of Texas M. D. Anderson Cancer Center. The findings were reported at the Society of Gynecologic Oncologists 39th Annual Meeting on Women's Cancers........ ]]> http://medicineworld.org/cancer/lead/2-2008/early-stage-ovarian-cancer.html http://medicineworld.org/cancer/lead/2-2008/early-stage-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT Scientists at Yale School of Medicine have developed a blood test with enough sensitivity and specificity to detect early stage ovary cancer with 99 percent accuracy. Results of this new study are reported in the February 15 issue of the journal Clinical Cancer Research. The results build on work done by the same Yale group in 2005 showing 95 percent effectiveness of a blood test using four proteins........ ]]> http://medicineworld.org/cancer/lead/2-2008/why-certain-ovarian-cancers-develop-resistance.html http://medicineworld.org/cancer/lead/2-2008/why-certain-ovarian-cancers-develop-resistance.html Fri, 18 Apr 2008 02:09:07 GMT A team of scientists led by Fred Hutchinson Cancer Research Center has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to therapy with usually used platinum-based chemotherapy drugs such as cisplatin and carboplatin. They describe their research online Feb. 10 in the journal Nature........ ]]> http://medicineworld.org/cancer/lead/11-2007/predicting-the-future-in-ovarian-cancer.html http://medicineworld.org/cancer/lead/11-2007/predicting-the-future-in-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, BMC Medicine, reveals. The kisspeptins, a family of peptide hormones, and the receptor GPR54 have previously been linked to anti-metastatic activity in certain human tumours. In this study, scientists have shown that kisspeptin and GPR54 are independent prognostic biomarkers specific for ovarian clear cell carcinoma - the first such markers to be identified........ ]]> http://medicineworld.org/cancer/lead/10-2007/avastin-improves-ovarian-cancer-treatment.html http://medicineworld.org/cancer/lead/10-2007/avastin-improves-ovarian-cancer-treatment.html Fri, 18 Apr 2008 02:09:07 GMT A new study appearing in International Journal of Gynecological Cancer states that Bevacizumab, a biologic anti-cancer agent that prevents tumor growth by interfering with the formation of new blood vessels, may have the potential to improve the efficacy of standard combination chemotherapy in ovary cancer........ ]]> http://medicineworld.org/cancer/lead/10-2007/low-fat-dietary-to-lower-risk-of-ovarian-cancer.html http://medicineworld.org/cancer/lead/10-2007/low-fat-dietary-to-lower-risk-of-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT A diet low in fat could reduce the risk of ovary cancer in healthy postmenopausal women, as per new results from the Women's Health Initiative (WHI) Dietary Modification Trial. Scientists observed that after four years, women who decreased the amount of dietary fat they consumed were 40 percent less likely to develop ovary cancer than women who followed normal dietary patterns. As expected, no effect was found during the first four years because preventive benefits on cancer often take a number of years to develop. Ovary cancer affects about 1 in 60 U.S. women in their lifetimes and has the highest mortality of all cancers of the female reproductive system........ ]]> http://medicineworld.org/cancer/lead/9-2007/recurrent-ovarian-cancer-patients.html http://medicineworld.org/cancer/lead/9-2007/recurrent-ovarian-cancer-patients.html Fri, 18 Apr 2008 02:09:07 GMT New clinical data showed an experimental drug called pertuzumab prolonged the survival time for women with recurrent ovary cancer, a University of Alabama at Birmingham doctor said recently. The data was presented Sept. 24 during a scientific session of the 14th European Cancer Conference held in Barcelona, Spain. The session's main speaker was Sharmila Makhija, M.D., an associate professor in UAB's Division of Gynecologic Oncology........ ]]> http://medicineworld.org/cancer/lead/9-2007/mutation-of-the-cox2-gene-and-ovarian-cancer.html http://medicineworld.org/cancer/lead/9-2007/mutation-of-the-cox2-gene-and-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT Scientists in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovary cancer, increasing womens susceptibility to developing the disease. The discovery raises the possibility that, if the findings are confirmed by further studies, it might be possible to use non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, which are used already for other conditions, to prevent ovary cancer developing in women with the COX2 mutation........ ]]> http://medicineworld.org/cancer/lead/8-2007/cranberries-may-improve-chemotherapy.html http://medicineworld.org/cancer/lead/8-2007/cranberries-may-improve-chemotherapy.html Fri, 18 Apr 2008 02:09:07 GMT Compounds in cranberries may help improve the effectiveness of platinum drugs that are used in chemotherapy to fight ovary cancer, scientists have found in a laboratory study that will be reported today at the 234th national meeting of the American Chemical Society. The researchers demonstrated in cell culture studies that human ovary cancer cells resistant to platinum drugs became up to 6 times more sensitized to the drugs after exposure to the cranberry compounds compared to cells that were not exposed to the compounds, which were obtained from juice extracts........ ]]> http://medicineworld.org/cancer/lead/6-2007/warning-signs-of-ovarian-cancer.html http://medicineworld.org/cancer/lead/6-2007/warning-signs-of-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT Cancer experts have identified a set of health problems that may be symptoms of ovary cancer, and they are urging women who have the symptoms for more than a few weeks to see their doctors. The new advice is the first official recognition that the disease, long believed to give no warning until it was far advanced, does cause symptoms at earlier stages in a number of women........ ]]> http://medicineworld.org/cancer/lead/3-2007/women-without-regular-medical-care.html http://medicineworld.org/cancer/lead/3-2007/women-without-regular-medical-care.html Fri, 18 Apr 2008 02:09:07 GMT In North America, ovary cancer is the second most common gynecological cancer and is the leading cause of death among women with gynecological cancer. The high mortality is in part due to the difficulty of detecting and diagnosing this condition at an early stage. In this case-control study, Abenhaim and his colleagues examined whether the frequency of medical visits and pelvic examinations and the type of health care provider visited had an effect on the risk of ovary cancer. They observed that women who did not have an annual medical visit or pelvic examination and who had no regular health care provider were at an increased risk of ovary cancer. This risk was most pronounced among postmenopausal women. Eventhough the study could not determine whether women who sought regular health care and had a regular doctor were at a decreased risk of ovary cancer, the most prudent recommendation is that women, particularly those who are postmenopausal, should be encouraged to maintain regular health care........ ]]> http://medicineworld.org/cancer/lead/3-2007/smart-therapies-for-breast-ovarian-cancer.html http://medicineworld.org/cancer/lead/3-2007/smart-therapies-for-breast-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT New non-toxic and targeted therapies for metastatic breast and ovary cancers may now be possible, thanks to a discovery by a team of scientists at the University of British Columbia. In a collaboration between UBC stem cell and cancer scientists, it was observed that a protein called podocalyxin which the scientists had previously shown to be a predictor of metastatic breast cancer changes the shape and adhesive quality of tumour cells, affecting their ability to grow and metastasize. Metastatic cancer is invasive cancer that spreads from the original site to other sites in the body........ ]]> http://medicineworld.org/cancer/lead/9-2006/radiofreqency-ablation-for-ovarian-cancer.html http://medicineworld.org/cancer/lead/9-2006/radiofreqency-ablation-for-ovarian-cancer.html Fri, 18 Apr 2008 02:09:07 GMT Percutaneous radiofrequency ablation, a procedure that uses a high frequency electric current to kill tumor cells, is effective in achieving local control in selected patients with metastasis from ovary cancer, as per a preliminary study conducted by the department of radiology at Massachusetts General Hospital in Boston, MA........ ]]>