How dietary restriction slows down agingUniversity of Washington researchers have uncovered details about the mechanisms through which dietary restriction slows the aging process. Working in yeast cells, the scientists have linked ribosomes, the protein-making factories in living cells, and Gcn4, a specialized protein that aids in the expression of genetic information, to the pathways correlation to dietary response and aging. The study, which was led by UW faculty members Brian........Go to the Research news blog (Added on 4/17/2008 8:14:05 PM)
Drug compound leads to death of ovarian cancer cellsIn a discovery that may be useful for maintaining remission in chemo-resistant ovary cancer, Yale researchers report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovary cancer cells by halting the activation of a protein pathway called mTOR.
Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine, and associate research scientist........Go to the Ovarian cancer blog (Added on 4/17/2008 7:47:46 PM)
MU researchers find clue to cataract formationIt is the No. 1 line-item cost of Medicare reimbursement and affects more than 20 million people in the United States. Cataracts, which can have devastating effects on the eye, affect 42 percent of the population between the ages of 70 and 80, and 68 percent of the population over the age of 80, as per the National Eye Institute. Now, a University of Missouri professor has identified an important step in how cataracts form. This discovery,........Go to the Ophthalmology news blog (Added on 4/17/2008 7:43:04 PM)
Inherited colon cancer mutation is widespreadA gene mutation responsible for the most common form of inherited colon cancer is older and more common than formerly believed, as per a recent study.
The findings provide a better understanding of the spread and prevalence of the American Founder Mutation, a common cause in North America of Lynch syndrome, a hereditary cancer syndrome that greatly increases a persons risk for developing cancers of the colon, uterus and ovaries.
The same........Go to the Colon-cancer-blog (Added on 4/17/2008 7:41:34 PM)
Lapatinib shrinks breast cancer tumors in just 6 weeksA drug that targets the cell surface receptors that play an important role in a number of types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6) today (Thursday 17 April). Dr. Angel Rodriguez, from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, USA, said that the work shown for the first time........Go to the Breast-cancer-blog (Added on 4/17/2008 3:53:38 AM)
Screening mammography in elderly patientsEventhough guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, as per a recent study conducted by scientists at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.
Our initial interest was sparked by the changing mammographic guidelines in the elderly........Go to the Breast-cancer-blog (Added on 4/13/2008 9:45:48 PM)
Macadamia nuts can be included in heart healthy diet Macadamia nuts included in a heart healthy diet reduced low-density cholesterol (bad cholesterol) and should be included among nuts with qualified health claims, as per researchers.
"We looked at macadamia nuts because they are not currently included in the health claim for tree nuts, while other tree nuts are currently recommended as part of a heart healthy diet," says Dr. Amy E. Griel, a recent Penn State Ph.D. recipient in nutrition and........Go to the Heart-watch-blog (Added on 4/13/2008 9:32:28 PM)
Disparities in depressionOlder Puerto Ricans have higher rates of depression than other Hispanics living in the United States, as per a new study by scientists at Hebrew SeniorLifes Institute for Aging Research (IFAR).
Nearly 7 percent of Puerto Ricans, who make up 11 percent of the Hispanics 65 and older in the U.S., suffer from major depression, in comparison to Mexican Americans, Cuban Americans, and Hispanics from Central and South America. Only 2.8 percent of........Go to the Psychology news blog (Added on 4/13/2008 9:08:04 PM)
Exercise may lead to faster prostate tumor growthProstate tumors grew more quickly in mice who exercised than in those who did not, leading to speculation that exercise may increase blood flow to tumors, as per a new study by scientists in the Duke Comprehensive Cancer Center (DCCC) and the Duke Prostate Center.
Our study showed that exercise led to significantly greater tumor growth than a more sedentary lifestyle did, in this mouse model, said Lee Jones, Ph.D., a researcher in the DCCC........Go to the Prostate-cancer-blog (Added on 4/13/2008 8:56:31 PM)
Smoking related to subset of colorectal cancersSmoking puts older women at significant risk for loss of DNA repair proteins that are critical for defending against development of some colorectal cancers, as per research from a team led by Mayo Clinic scientists.
In a study being presented at the annual meeting of the American Association for Cancer Research (AACR), the scientists observed that women who smoked were at increased risk for developing colorectal tumors that lacked some or........Go to the Colon-cancer-blog (Added on 4/13/2008 8:53:58 PM)
Mouth may tell the tale of lung damageCells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, scientists at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research.
Examining oral tissue lining the mouth to gauge cancer-inducing molecular alterations in the lungs could spare patients and those at risk of lung cancer from more invasive, uncomfortable........Go to the Lung-cancer-blog (Added on 4/13/2008 8:44:49 PM)
Wine may protect against dementiaThere may be constituents in wine that protect against dementia. This is shown in research from the Sahlgrenska Academy at University of Gothenburg in Sweden.
The findings are based on 1,458 women who were included in the so-called Population Study of Women from 1968. When they were examined by physicians they were asked to report how often they drank wine, beer, and liquor by selecting from seven categories on a scale from never to daily.........Go to the Neurology news blog (Added on 4/10/2008 9:23:57 PM)
The good and bad side of anti-cancer compoundsCompounds known as HDAC inhibitors exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear.
In a pair of recent papers, Vanderbilt-Ingram Cancer Center researchers provide a potential mechanism by which HDAC inhibitors specifically damage cancer cells and offer clues about possible adverse effects of these compounds ........Go to the Cancer-blog (Added on 4/10/2008 9:10:06 PM)
Language Development in InfantsUncover how the brains of infants distinguish differences in sounds and it may become possible to correct language problems even before children start to speak, sparing them the difficulties that come from struggling with language.
New studies conducted by Professor of Neuroscience April Benasich and her Infancy Studies Laboratory at Rutgers University in Newark are revealing new and exciting clues about how infant brains begin to acquire........Go to the Pediatric news blog (Added on 4/10/2008 9:01:59 PM)
Traffic exhaust can cause asthmaChildren exposed to high levels of air pollution during their first year of life run a greater risk of developing asthma, pollen allergies, and impaired respiratory function. However, genetic factors are also at play. These are the results of a new study conducted under the BAMSE project.
The BAMSE project has monitored 4,000 children in Stockholm county from birth in order to assess whether exposure to traffic pollution during their first........Go to the Allergy news blog (Added on 4/9/2008 10:12:14 PM)
Omega-3 intake during last months of pregnancyA study supervised by Universit Laval scientists Gina Muckle and ric Dewailly reveals that omega-3 intake during the last months of pregnancy boosts an infants sensory, cognitive, and motor development. The details of this finding are published in a recent edition of the Journal of Pediatrics.
To come to this conclusion, scientists first measured docosahexaenoic acid (DHA) concentrationa type of omega-3 fatty acid involved in the development........Go to the OBGYN news blog (Added on 4/9/2008 10:10:15 PM)
How Fast You'll Age is Written in the BonesPerhaps the aging process can't be stopped. But it can be predicted, and new research from Tel Aviv University indicates that people may live longer and lead healthier lives as a result.
Scientists have developed a new biological marker that represents the age of a body's bones. It reveals that the speed of physical aging is strongly influenced by genetics.
Christened the osseographic score (OSS), this new marker can be used by doctors........Go to the Society medical news blog (Added on 4/9/2008 9:58:52 PM)
Study on egg consumptionA study reported in the April 2008 issue of The American Journal of Clinical Nutrition(1) suggests an association between high egg consumption and all-cause mortality, an unusual finding for which the scientists do not provide an explanation. The researchers, Djouss and Gaziano, analyzed data from the Physicians Health Study I which followed male physicians over a 20 year period.
The fact is, healthy adults can continue to enjoy eggs as........Go to the Society medical news blog (Added on 4/9/2008 9:45:49 PM)
Pistachios are smart for the heartMore good news for pistachio fans! As per new data unveiled this week at the Experimental Biology Conference in San Diego, snacking on pistachios has proved once again to have a positive impact on improving cardiovascular health by significantly reducing inflammation in the body, a prominent cardiovascular disease (CVD) risk factor.
CVD remains the number one cause of death in the U.S., with millions more Americans currently living with the........Go to the Heart-watch-blog (Added on 4/8/2008 10:22:33 PM)
Marijuana increases alcohol toxicityMarijuana is among the most frequently used illicit drugs by women during their childbearing years and there is growing concern that marijuana abuse during pregnancy, either alone or in combination with other drugs, may have serious effects on fetal brain development. There is good evidence that THC, the main psychoactive component of marijuana, crosses the placenta, that maternal marijuana abuse results in intrauterine growth retardation and........Go to the Society medical news blog (Added on 4/8/2008 10:13:33 PM)
Breakthrough in migraine geneticsMigraine is the most common cause of episodic headache, and by far the most common neurological cause of a doctors visit. It affects some 15% of the population, including some 41 million people in Europe, and places a considerable burden on healthcare in both the developed and the developing world.
During the last few years, great strides have been made in discovering common genes influencing the susceptibility to common diseases, such as........Go to the Neurology news blog (Added on 4/17/2008 8:26:37 PM)
Ovarian cancer stem cells identifiedScientists at Yale School of Medicine have identified, characterized and cloned ovary cancer stem cells and have shown that these stem cells may be the source of ovary cancers recurrence and its resistance to chemotherapy.
These results bring us closer to more effective and targeted therapy for epithelial ovary cancer, one of the most lethal forms of cancer, said Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology........Go to the Ovarian cancer blog (Added on 4/17/2008 8:09:10 PM)
Parents stricter with older kids to set exampleParents are more likely to punish their teen's risky behavior when there are younger kids in the family, driven by a desire to set a strict example for these siblings, says new game theory research from the University of Maryland, Duke University and The Johns Hopkins University.
The research team used economic game theory to predict levels of parental discipline. Parental concern for their reputation as a disciplinarian with the younger........Go to the Society medical news blog (Added on 4/17/2008 7:45:55 PM)
Slight Of Hand Is Not So SlightTyping on a keyboard or scribbling on paper may be similar activities, but there is a significant difference in how the body moves, as per new motor development research.
"In language we start with letters that lead to syllables that lead to words, and we use grammar to put everything together," said Howard N. Zelaznik, a Purdue University professor of health and kinesiology. "One of the fundamental questions in motor control is whether........Go to the Neurology news blog (Added on 4/17/2008 7:28:57 PM)
Capecitabine combo produces side effectsAdding capecitabine, a drug that inhibits DNA synthesis and slows the growth of tumour tissue, to docetaxel, in patients with early breast cancer, leads to more toxicities and does not improve the efficacy of therapy, a German scientist told the 6th European Breast Cancer Conference (EBCC-6) today (Thursday 17 April). Previously, such a combination had improved patient survival in metastatic disease, where the cancer has spread to other parts........Go to the Breast-cancer-blog (Added on 4/17/2008 3:56:04 AM)
Standard chemo works better against BRCA2 related breast cancerThe first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation.
The authors of a study presented today (Thursday) at the 6th European Breast Cancer Conference (EBCC-6) in Berlin observed that women with BRCA2-associated breast cancer had a significantly higher........Go to the Breast-cancer-blog (Added on 4/17/2008 3:31:07 AM)
Keep Boys and Girls TogetherBoys and girls may learn differently, but American parents should think twice before moving their children to sex-segregated schools. A new Tel Aviv University study has observed that girls improve boys' grades markedly at school.
"Being with more girls is good for everybody," says Prof. Analia Schlosser, an economist from the Eitan Berglas School of Economics at Tel Aviv University. "We find that both boys and girls do better when there are........Go to the Society medical news blog (Added on 4/13/2008 9:27:07 PM)
Radiation beneficial for older breast cancer patientsA patients with breast cancer age alone should not determine whether or not she receives standard breast-conservation therapys, including a lumpectomy and radiation treatment; however, if additional health problems (comorbidities) are present, therapys should be individualized based on age and the type of comorbidities, as per a research studyin the April 1 edition of the International Journal for Radiation Oncology*Biology*Physics, the........Go to the Breast-cancer-blog (Added on 4/13/2008 9:12:12 PM)
Autism and muscle weaknessSome kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 1219, 2008.
The study looked at 37 children with autism spectrum disorders who were evaluated for mitochondrial disease,.
which causes muscle weakness and prevents a child from being able to participate in physical activities and.
........Go to the Pediatric news blog (Added on 4/13/2008 9:05:42 PM)
A genetic cause for iron deficiencyThe discovery of a gene for a rare form of inherited iron deficiency may provide clues to iron deficiency in the general population especially iron deficiency that doesnt respond to iron supplements - and suggests a new therapy approach. The finding was published online by the journal Nature Genetics on April 13.
Iron deficiency is the most common nutritional deficiency and the leading cause of anemia in the United States.(1) Most cases........Go to the Research news blog (Added on 4/13/2008 8:48:19 PM)
Connection between protein and prognosis in breast cancerOregon Health & Science University Cancer Institute scientists have observed that a tumor protein present in an aggressive form of breast cancer is correlation to a poor prognosis.
The presence of the protein, called growth factor receptor-bound protein-7, often referred to as GRB-7, in breast cancer tumors, is strongly correlation to the growth and spread of the cancer, as per principal investigator Shiuh-Wen Luoh, M.D., Ph.D., assistant........Go to the Breast-cancer-blog (Added on 4/13/2008 8:43:08 PM)
Targeted therapy combination for liver cancerScientists at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported today at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes therapy resistance in liver cancer cell lines. The team is currently designing a trial to test the combination in patients.
Liver cancer is resistant to a number of chemotherapies and to cell-death inducing agents. Last........Go to the Cancer-blog (Added on 4/13/2008 8:41:33 PM)
Developing targeted chemotherapyScientists from the University of Pennsylvania School of Medicine and his colleagues discovered that the Notch signaling pathway, which determines the development of a number of cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. The findings appear this week in Cell Stem Cell, and indicate that inhibitors of Notch may not affect bone marrow stem cells.
Notch is one of a select........Go to the Cancer-blog (Added on 4/10/2008 9:17:50 PM)
Carotid stenting as alternative to surgeryCarotid artery stenting is an effective option for high risk patients who are not eligible for surgery, as per a long-term study published in this weeks New England Journal (NEJM). Carotid artery disease, which involves clogging of the arteries in the neck that provide blood to the brain, is a significant risk factor for stroke, making these study results important for the estimated 200,000 Americans each year who would otherwise not be........Go to the Health news blog (Added on 4/10/2008 9:08:49 PM)
Men with Serious Injuries Often Abuse AlcoholMen with serious injuries, such as traumatic brain injury or spinal cord injury, must deal with a range of emotions. If these men have strong traditional masculine ideas and abuse alcohol, it becomes even more difficult to help them heal and come to terms with their emotions and situations. A University of Missouri psychology researcher studied these challenging factors to find better ways to understand and treat men who fit this mold, such as........Go to the Psychology news blog (Added on 4/10/2008 8:20:34 PM)
Your neighborhood can affect your healthResearch carried out at the Peninsula Medical School, South West England, has found strong links between neighbourhood deprivation and the physical and intellectual health of older people.
Two studies were conducted, both using data on participants in the English Longitudinal Study of Ageing (ELSA).
The first study investigated over 7,000 individuals aged 52 and older who lived in urban areas across England. The study observed that even........Go to the Society medical news blog (Added on 4/9/2008 10:03:47 PM)
A Serious Illness Occurs Later In LifeA new study underscores the need for seniors to maintain their health -- in order to maintain their wealth.
Building on a 2003 study that observed that healthy seniors are more likely to retain their savings, Ohio State University scientists have now discovered that the during the later part of life a serious illness occurs, the more damage it does to a person's finances.
The study observed that when seniors develop a new and serious........Go to the Society medical news blog (Added on 4/9/2008 9:55:49 PM)
Forecasting Physicians' Choice of Prescriptions?Physicians' choice of prescriptions are often influenced by patients, with patient experience with specific drugs playing a strong role, as per the Management Insights feature in the current issue of Management Science, the flagship journal of the Institute for Operations Research and the Management Sciences (INFORMS®). The results have important implications for those who market pharmaceuticals.
Management Insights, a regular feature of........Go to the Society medical news blog (Added on 4/9/2008 9:43:07 PM)
First do no harm?One month of tough breathing may help asthma sufferers breathe easier in the long run, as per research from one University of Houston professor.
In a move that challenges one of the most basic tenets of the Hippocratic Oath first do no harm Richard Bond, associate professor of pharmacology at UH, is relying on a long-standing medical taboo to treat asthma. Eventhough counterintuitive, Bonds studies are reminiscent of hair-of-the-dog folk........Go to the Allergy news blog (Added on 4/9/2008 8:45:26 PM)
Back pain may be in your genesWhat do you learn by looking at the spines of hundreds of Finnish twins? If you are the international team of scientists behind the Twin Spine Study, you find compelling proof that back pain problems may be more a matter of genetics than physical strain.
The findings of the Twin Spine Study, an ongoing research program started in 1991, have led to a dramatic paradigm shift in the way disc degeneration is understood. Last month a paper........Go to the Rheumatology news blog (Added on 4/8/2008 10:01:08 PM)