High prevalence of eating disorders in narcolepticsThe majority of patients with narcolepsy/cataplexy experience many symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, as per a research studyreported in the March 1 issue of the journal SLEEP.
The study, authored by Hal Droogleever Fortuyn, MD, and Sebastiaan Overeem, MD, of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients with........Go to the Weight watcher's blog (Added on 3/2/2008 8:48:42 PM)
Methylphenidate can have sleep benefitsTreatment with methylphenidate (MPH) appears to have beneficial effects on sleep parameters in adults with ADHD, including increased sleep efficiency and a feeling of improved restorative value of sleep, as per a research studyreported in the March 1 issue of the journal SLEEP.
The study, authored by Esther Sobanski, MD, of the Central Institute of Mental Health in Mannheim, Gera number of, focused on 34 non-medicated patients with ADHD, of........Go to the Psychology news blog (Added on 3/2/2008 8:43:27 PM)
Steps leading to celiac diseaseResearchers who last year identified a new genetic risk factor for coeliac disease, have, following continued research, discovered an additional seven gene regions implicated in causing the condition. The team, lead by David van Heel, Professor of Gastrointestinal Genetics at Barts and The London School of Medicine and Dentistry, have further demonstrated that of the nine coeliac gene regions now know, four of these are also predisposing........Go to the GI news blog (Added on 3/2/2008 8:35:03 PM)
Heightened Weighing Discomfort Among WomenA new study from the University of Pennsylvania points to increased health risks for women owing to their higher level of discomfort about being weighed in public.
The study showed that college-age females, more than their male counterparts, experience high degrees of discomfort at the prospect of being weighed in the presence of others.
The study's authors think that some women may avoid necessary tests and therapys when a doctor visit........Go to the Weight watcher's blog (Added on 2/28/2008 10:33:39 PM)
Depressed Teens Respond Well To Combination TherapyMore than half of teenagers with the most debilitating forms of depression that do not respond to therapy with selective serotonin reuptake inhibitors (SSRIs) show improvement after switching to a different medicine combined with cognitive behavioral treatment, scientists at UT Southwestern Medical Center and their colleagues in a multicenter study have found.
Dr. Graham Emslie, professor of psychiatry and pediatrics at UT Southwestern and........Go to the Psychology news blog (Added on 2/26/2008 10:30:27 PM)
Bacterial 'battle for survival' leads to new antibioticBiologists have provoked soil-dwelling bacteria into producing a new type of antibiotic by pitting them against another strain of bacteria in a battle for survival.
The antibiotic holds promise for therapy of Helicobacter pylori, which causes stomach ulcers in humans. Also, figuring out the still murky explanation for how the new antibiotic was produced could help researchers develop strategies for finding other new antibiotics.
The work........Go to the Infectious disease blog (Added on 2/26/2008 10:24:40 PM)
Test can reduce recurrence of breast cancerA new test that examines large sections of the sentinel lymph node for genes expressed by breast cancer could reduce the risk of recurrence and multiple surgeries, doctors say.
The GeneSearch Breast Lymph Node Assay, manufactured by Veridex, L.L.C., a Johnson & Johnson company, is being used at the Medical College of Georgia to examine half of the tissue in the sentinel lymph node, the first place breast cancer typically spreads. The sample........Go to the Breast-cancer-blog (Added on 2/25/2008 9:14:01 PM)
Many Stroke, Heart Attack Patients May Not Benefit from AspirinUp to 20 percent of patients taking aspirin to lower the risk of suffering a second cerebrovascular event do not have an antiplatelet response from aspirin, the effect thought to produce the protective effect, scientists at the University at Buffalo have shown.
"Millions of people use low-dose aspirin either for prevention of a second stroke, second heart attack or second episode of peripheral artery disease," said Francis M. Gengo,........Go to the Heart-watch-blog (Added on 2/25/2008 8:58:21 PM)
Empty Nest Syndrome May Not Be Bad After All,One day they are crawling, the next day they are driving and then suddenly they aren't kids anymore. As children reach adulthood, the parent-child relationship changes as parents learn to adapt to newly independent children. A new study by a University of Missouri professor explored the differences in how mothers and fathers interacted with their young adult children. She found there were few differences in the way mothers and fathers felt and........Go to the Society medical news blog (Added on 2/24/2008 10:12:09 PM)
Children Who Do Not Get Enough SleepLack of adequate sleep can lead to increased injuries among preschool children, new research shows. This study published in Public Health Nursing shows that the average number of injuries during the preschool years is two times higher for children who don't get enough sleep each day as described by their mothers.
Each year approximately 20-25 percent of all children in the United States sustain injuries that require medical attention.........Go to the Pediatric news blog (Added on 2/24/2008 10:06:45 PM)
Optimal care for inflammatory bowel diseaseInflammatory bowel disease (IBD) is a chronic recurrent gastrointestinal disease. The disease has a relatively higher morbidity in young adults, in whom growth, education, employment and wellbeing all are adversely influenced. Many guidelines for management of inflammatory bowel disease are available for bringing evidence-based medicine into full play to improve IBD patient care. What about the actual quality of care for patients with IBD in........Go to the GI news blog (Added on 2/24/2008 9:38:38 PM)
5-fluorouracil in colonic neoplasm?5-fluorouracil (5-FU) is a common chemotherapeutical drug. It exerts its antitumor effect through competitive thymidylate synthase (TS) inhibition. Thymidylate synthase (TS) catalyses deoxyuridine-5-monophosphate (dUMP) to 2-deoxythymydine-5-monophosphate (dTMP). It is the only de novo source of thymidylate, an essential precursor of DNA biosynthesis. In the 5-untranslated region of TS gene, there a unique tandem repeated sequence. There are........Go to the Colon-cancer-blog (Added on 2/24/2008 9:36:17 PM)
Novel approach strips staph of virulenceAn international team of scientists supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent. The novel approach, described in the February 14 online edition of Science, could offer a new direction for therapies against a bacterium thats becoming increasingly resistant to antibiotics.
By following their scientific instinct about........Go to the Infectious disease blog (Added on 2/14/2008 10:28:57 PM)
Single reader with CAD more efficientSingle reading of screening mammograms with computer-aided detection (CAD) is more efficient than double reading and yields a higher sensitivity than the first reader in a double reading program, as per a research studyconducted by scientists at Charlotte Radiology in Charlotte, NC. In addition, the readings with CAD had a significantly lower recall rate than double reading.
The double reading method consisted of the mammogram being first........Go to the Breast-cancer-blog (Added on 2/14/2008 10:19:15 PM)
Exercise to avoid gallstones!A new University of Illinois study shows that exercise-trained mice get far fewer gallstones than sedentary mice and identifies potential mechanisms to explain why this occurs.
The study, recently reported in the Journal of Applied Physiology, can be viewed online at: http://jap.physiology.org/cgi/reprint/01292.2007v1.
For the first time, we have direct evidence that physical activity reduces gallstone formation, adding to the........Go to the Weight watcher's blog (Added on 2/13/2008 9:35:53 PM)
Earlier colon cancer screening for smokersNew evidence suggests screening for colorectal cancer, which is now recommended to begin at age 50 for most people, should start five to 10 years earlier for individuals with a significant lifetime exposure to tobacco smoke, a University of Rochester Medical Center study said.
An examination of 3,450 cases observed that current smokers were diagnosed with colon cancer approximately seven years earlier than people who never smoked. The study........Go to the Colon-cancer-blog (Added on 2/13/2008 9:23:00 PM)
Test detects early stage ovarian cancer with 99 percent accuracyScientists at Yale School of Medicine have developed a blood test with enough sensitivity and specificity to detect early stage ovary cancer with 99 percent accuracy.
Results of this new study are reported in the February 15 issue of the journal Clinical Cancer Research. The results build on work done by the same Yale group in 2005 showing 95 percent effectiveness of a blood test using four proteins.
The ability to recognize almost 100........Go to the Ovarian cancer blog (Added on 2/12/2008 9:41:20 PM)
Gene research to explain autistic savantsMice lacking a certain brain protein learn some tasks better but also forget faster, as per new research from MIT that may explain the phenomenon of autistic savants in humans. The work could also result in future therapys for autism and other brain development disorders.
Scientists at the Picower Institute for Learning and Memory at MIT report in the Feb. 13 issue of the Journal of Neuroscience that mice genetically engineered to lack a key........Go to the Psychology news blog (Added on 2/12/2008 9:20:19 PM)
Hostility, Depression And Heart DiseaseScientists led by Jesse Stewart, Ph.D., assistant professor of psychology at Indiana University-Purdue University Indianapolis, report that hostility and depression appear to act together in a complex way to elevate inflammatory proteins in the human body, possibly putting hostility plus depression on the list of risk factors for heart disease along with high blood pressure, elevated cholesterol, and smoking.
The findings, that hostility........Go to the Psychology news blog (Added on 2/11/2008 10:46:18 PM)
High School to the First Year of CollegeIncreases in young women's drinking during the transition from high school through the first year of college can have dangerous physical, sexual and psychological implications, as per a report out of the University at Buffalo's Research Institute on Addictions.
The good news is that during the first year of college, when a number of young women increase their drinking, the majority (78 percent) of the 870 incoming freshmen women who took........Go to the Society medical news blog (Added on 2/10/2008 10:00:21 PM)
Snoring linked to cardiovascular diseaseLoud snoring with breathing pauses is linked to an increased risk of cardiovascular disease and increased health care utilization, as per a research studyreported in the March 1 issue of the journal SLEEP.
The study, authored by Marta Novak, MD, PhD, of the Institute of Behavioral Sciences at Semmelweis University in Budapest, Hungary, focused on interviews with 12,643 Hungarian individuals. Interviews were carried out in the homes of the........Go to the Heart-watch-blog (Added on 3/2/2008 8:52:21 PM)
Mouse model for speed drug huntFrustrated by the slow pace of new drug development for a condition that causes pediatric brain tumors, a neurologist at Washington University School of Medicine in St. Louis decided to try to fine-tune the animal models used to test new drugs.
Instead of studying one mouse model of the disease causing the brain tumors, the laboratory of David Gutmann, M.D., Ph.D., the Donald O. Schnuck Family Professor of Neurology, reviewed three. They........Go to the Pediatric news blog (Added on 3/2/2008 8:45:22 PM)
Novel way to develop tumor vaccinesScientists at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. The results of the study, titled A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression, will be published in Nature Medicine on March 2, 2008.
Under normal circumstances, regulatory T cells inhibit the........Go to the Cancer-blog (Added on 3/2/2008 7:37:27 PM)
Breast cancer death rates among black womenA new study from the American Cancer Society finds that while breast cancer death rates are decreasing for white women in every U.S. state, for African American women, death rates are either flat or rising in at least half the states. The study, published early online in the journal Cancer Causes and Control, finds breast cancer death rates among African American women are decreasing in only 11 of 37 states with sufficient numbers for analysis........Go to the Breast-cancer-blog (Added on 2/28/2008 10:39:13 PM)
Targets Against Hormone-Dependent Breast CancerThe identification of two cellular receptors that likely contribute to the genesis of hormone-dependent breast cancer points the way to new, highly targeted therapies against the disease, says a team led by researchers at Weill Cornell Medical College in New York City.
The finding also helps explain how daily use of medicines such as aspirin might help keep these breast tumors at bay.
"These two receptors, called EP2 and EP4, form key........Go to the Breast-cancer-blog (Added on 2/28/2008 10:24:00 PM)
New bladder cancer therapyAs a number of as half of patients with superficial bladder cancer do not respond to the standard first-line chemotherapy placed into the bladder, as per current multi-center outcomes data. When this happens, typically, their only option is surgical removal of the bladder. Now, scientists at the Herbert Irving Comprehensive Cancer Center of NewYork-Presbyterian Hospital and Columbia University Medical Center are investigating an FDA-approved........Go to the Cancer-blog (Added on 2/26/2008 10:12:20 PM)
Tropics Are Next Emerging Disease HotspotResearchers from four well-known institutions say the next major disease like HIV/AIDS or SARS could occur in any of many developing countries concentrated along the equator. They encourage increased surveillance to prevent the spread of a potential outbreak.
Using global databases and sophisticated computer models to analyze patterns of emerging diseases, the scientists -- from the Consortium for Conservation Medicine (CCM) at Wildlife........Go to the Infectious disease blog (Added on 2/26/2008 4:55:38 PM)
Mother's antibody production may affect fetal brainThe mothers of some autistic children may have made antibodies against their fetuses brain tissue during pregnancy that crossed the placenta and caused changes that led to autism, suggests research led by Johns Hopkins Childrens Center researchers and reported in the recent issue of the Journal of Neuroimmunology.
The causes of autism, a disorder manifesting itself with a range of brain problems and marked by impaired social interactions,........Go to the OBGYN news blog (Added on 2/25/2008 9:01:13 PM)
Women With HIV Want To Become PregnantAbout one in four women who have tested positive for the human immunodeficiency virus (HIV) expect pregnancy and motherhood to be a part of their future, recent research suggests.
A woman's age at the time she learns of her HIV status appears to influence this decision. Women in an Ohio State University study who learned of their HIV infection when they were under age 30 were almost four times more likely to say they wanted to become........Go to the Infectious disease blog (Added on 2/25/2008 8:54:37 PM)
Obesity and risk of strokeMiddle-aged women's waists aren't the only thing that increased in the last decade. So did their chance of stroke. In a new study reported at the American Stroke Association's International Stroke Conference 2008, rising obesity rates have been associated with more strokes among women aged 35 to 54.
A prior analysis of stroke prevalence rates in the United States from 1999 to 2004 revealed that women in their midlife years were more than........Go to the Health news blog (Added on 2/24/2008 9:52:47 PM)
Novel method to reveal drug targetsWellcome Trust Sanger Institute researchers have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention. The novel method can identify the weak, short-lived interactions that are characteristic of cell responses to cues from the environment or from within the body.
Cell surface proteins are targets for a number of drugs and are central to a number of processes of........Go to the Health news blog (Added on 2/24/2008 9:49:12 PM)
Role of Antidepressants in cancer therapeuticsRecently I have seen an interesting article by Julian Lieb titled "The multifaceted value of antidepressants in cancer therapeutics" and I saw some very interesting concepts in this article. In this review I am trying to look in to some of the theories and findings presented by Dr. Julian Lieb in this article (Ref 1).
Julian Lieb, M.D is a retired, Yale medical school psychiatry professor. His major interest is immunopharmacology of........Go to the Cancer-blog (Added on 2/21/2008 12:31:47 PM)
Cancer deaths down butNew data revealing decreasing trends in cancer deaths in the United States overall, and in colorectal cancer deaths in particular, highlight the remarkable benefits of colorectal cancer screening tests, but the lifesaving potential of these tests is unrealized for a number of Americans as per experts from the American College of Gastroenterology. Racial minorities, uninsured Americans and even Medicare patients who should be tested are not........Go to the Colon-cancer-blog (Added on 2/20/2008 8:04:39 AM)
Addressing global obesity epidemicAs per Rena Wing, professor of psychiatry and human behavior at The Warren Alpert Medical School of Brown University and director of the Weight Control & Diabetes Research Center at The Miriam Hospital, people who are most successful in preventing weight gain, and dieters who lose weight and keep the pounds off, have made major changes in their in diet and exercise routines.
Using new research findings, Wing will make her case for big........Go to the Weight watcher's blog (Added on 2/17/2008 10:42:16 PM)
Physicians Pinpoint Cause Of Children's SeizuresIt was no way for an 11-year-old to live. For a month the boy had endured daily episodes of uncontrollable jerking and foaming at the mouth, and his physicians at Lucile Packard Children's Hospital were concerned that the boy had epilepsy. Before starting the boy on a lifetime of anti-seizure medications, though, they turned to an unconventional diagnostic tool: hypnosis.
"Children are highly suggestible and they have great imaginations,"........Go to the Pediatric news blog (Added on 2/14/2008 10:09:20 PM)
When it comes to physical activityA landmark University of Alberta study, analyzing a sample of over 275,000 individuals, has observed that when it comes to participation in physical activity, one size does not fit all.
Our study uncovered some definite trends and preferences when deciding how and if a person wants to be physically active, says Brad Humphreys, an economics professor at the University of Alberta. It is clear that different genders, ethnicities and income........Go to the Weight watcher's blog (Added on 2/13/2008 9:27:47 PM)
Vaccine for stomach flu may be possibleEvery year, millions of people are infected with noroviruses - usually called stomach flu often resulting in up to 72 hours of vomiting and diarrhea. While most people recover in a few days, the symptoms can lead to dehydration and - in rare cases, particularly among the elderly and infants - death.
Now, scientists at the University of North Carolina School of Public Health have discovered that the virus mutates genetically, similar to the........Go to the Infectious disease blog (Added on 2/13/2008 9:20:13 PM)
HIV persists in the gut despite long-term therapyEven with effective anti-HIV therapies, doctors still have not been able to eradicate the virus from infected individuals who are receiving such therapys, largely because of the persistence of HIV in hideouts known as viral reservoirs. One important reservoir is the gut, where HIV causes much of its damage due to the large number of HIV target cells that reside there. These cells, known as CD4+ T cells, are largely contained in lymph nodes and........Go to the Infectious disease blog (Added on 2/13/2008 9:19:06 PM)
Body image is stronger predictor of health than obesityIn a study to examine the impact of desired body weight on the number of unhealthy days subjects report over one month, scientists at Columbia University Mailman School of Public Health observed that the desire to weigh less was a more accurate predictor of physically and mentally unhealthy days, than body mass index (BMI). In addition, the desire to lose weight was more predictive of unhealthy days among Whites than among African-Americans or........Go to the Weight watcher's blog (Added on 2/12/2008 9:34:28 PM)
Mechanism leading to cleft palateBy creating a genetic mutation in zebrafish, University of Oregon scientists say they've discovered a previously unknown mechanism for cleft palate, a common birth defect in humans that has challenged medical professionals for centuries.
Many molecular pathways in zebrafish are present in humans and other vertebrates. By studying the induced mutation in zebrafish, the 10-member research team isolated a disruption in early developmental........Go to the Research news blog (Added on 2/11/2008 10:36:40 PM)
Moss protein plays role in Alzheimer's DiseasePreventing Alzheimer's disease is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine. The moss plant Physcomitrella patens studied in the laboratory of Ralph S. Quatrano, Ph.D., the Spencer T. Olin Professor and chair of the biology department on WUSTL's Danforth Campus, might inch Kopan toward that goal. Here's how.
The gene presenilin (PS) in mammals provides the........Go to the Neurology news blog (Added on 2/10/2008 10:04:58 PM)