Old compound, new useThe compound, α-difluoromethylornithine or DFMO, targets the activity of a specific enzyme and, even in very limited doses, is effective in protecting against the malignancy in animal models.
The study was reported in the January 15, 2009 issue of the journal, Cancer Research (Volume 69, Issue 2).
"The drug, which was developed as a cancer treatment and later shelved because of toxicity concerns, has been around since the 1970s,"........Go to the Cancer-blog (Added on 1/15/2009 6:41:26 PM)
Breakthrough in Treating Premature BabiesAdelaide scientists have made a world breakthrough in treating premature babies at risk of developmental disorders.
A six-year study led by Dr Maria Makrides from the Women's & Children's Health Research Institute and Professor Bob Gibson from the University of Adelaide has demonstrated that high doses of fatty acids administered to pre-term infants via their mother's breast milk or infant formula can help their mental development.
The........Go to the Pediatric news blog (Added on 1/14/2009 11:43:50 PM)
Alzheimer's research based on family consentBy the time they have been diagnosed with Alzheimer's disease, a number of patients' decision-making ability is so impaired that they cannot give informed consent to participate in research studies.
Close family members are left with the decision, but there is no clear policy for this so-called "surrogate" consent. Because of that, research about the increasingly common disease is often stalled.
But a newly released study led by the........Go to the Neurology news blog (Added on 1/14/2009 11:34:54 PM)
A new protein that initiates breast cancerCanadian scientists have identified a novel protein in the advancement of breast cancer. As per a recent study from the Universit de Montral and the University of Alberta, reported in the Journal of Biological Chemistry, the protein ARF1 plays a critical role in cancer cell growth and the spread of tumours. Targeting this protein with drug treatment may provide hope to women with breast cancer.
"Until now, ARF1 has been linked to harmless........Go to the Breast-cancer-blog (Added on 1/14/2009 11:27:25 PM)
laparoscopic removal of GISTNew research reported in the recent issue of the Journal of the American College of Surgeons shows that laparoscopic removal of gastrointestinal stromal tumors (GISTs) is safe and effective, with a disease-free survival rate of nearly 80 percent after an average follow-up time of three and a-half years.
GIST is a type of cancer arising from special cells in the wall of the gastrointestinal tract that help coordinate the muscular movement of........Go to the GI news blog (Added on 1/14/2009 11:10:29 PM)
New gene to predict outcome in pancreatic cancerVariations in mismatch repair genes can help predict therapy response and prognosis in patients with pancreas cancer, as per research from The University of Texas M. D. Anderson Cancer Center presented today in advance of the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium.
In the study, single nucleotide polymorphisms (SNPs) in genes involved in DNA mismatch repair were linked to response to gemcitabine........Go to the Pancreatic cancer blog (Added on 1/14/2009 6:31:08 AM)
Cattle and sheep grazed on natural grasslandsCattle and sheep grazed on natural grasslands help maintain biodiversity and produce tastier, healthier meat, as per a research studyfunded by the Economic and Social Research Council (ESRC). The research, part of the Rural Economy and Land Use (RELU) programme which draws together the social and natural science, concluded that pasture-based farming is good for the environment, the consumer and the producer but needs stronger support from........Go to the Weight watcher's blog (Added on 1/14/2009 6:11:17 AM)
Cold weather leads to higher blood pressureOutdoor temperature and blood pressure appear to be correlated in the elderly, with higher rates of high blood pressure in cooler months, as per a report in the January 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Seasonal variations in blood pressure have been recognized among the general population for 40 years, as per background information in the article. However, few prior studies have looked........Go to the Heart-watch-blog (Added on 1/12/2009 11:53:54 PM)
Stress at workplace may increase risk of strokeJapanese men in high-stress jobs appear to have an increased risk of stroke compared with those in less demanding positions, as per a report in the January 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Stress is considered a risk factor for stroke, as per background information in the article. Several models of job stress have been developed and provide clues as to how occupational factors appears to be........Go to the Neurology news blog (Added on 1/12/2009 11:51:43 PM)
If you sleep less you catch coldIndividuals who get less than seven hours of sleep per night appear about three times as likely to develop respiratory illness following exposure to a cold virus as those who sleep eight hours or more, as per a report in the January 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Studies have demonstrated that sleep deprivation impairs some immune function, as per background information in the article. Research........Go to the Infectious disease blog (Added on 1/12/2009 11:46:49 PM)
Younger Adults Could Be At Risk For Heart DiseaseEven younger adults who have few short-term risk factors for heart disease may have a higher risk of developing heart disease over their lifetimes, as per new findings by a UT Southwestern Medical Center researcher.
The findings, based on clinical studies and appearing in the Jan. 26 issue of the journal Circulation: Journal of the American Heart Association, suggest that traditional methods of identifying heart disease risk might not........Go to the Heart-watch-blog (Added on 1/12/2009 11:43:04 PM)
Nanoparticles based drug delivery systemA tiny particle syringe composed of polymer layers and nanoparticles may provide drug delivery that targets diseased cells without harming the rest of the body, as per a team of chemical engineers. This delivery system could be robust and flexible enough to deliver a variety of substances.
"People probably fear the effects of some therapys more than they fear the disease they treat," says Huda A. Jerri, graduate student, chemical........Go to the Research news blog (Added on 1/12/2009 11:30:22 PM)
organic substance may help heal broken heartsImagine new therapys for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition. That's not hard to do thanks to Canadian researchers, who for the first time, have developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online in The FASEB Journal........Go to the Heart-watch-blog (Added on 1/12/2009 8:40:39 PM)
Where am I?We've all experienced the feeling of not knowing where we are. Being disoriented is not pleasant, and it can even be scary, but luckily for most of us, this sensation is temporary. The brain employs many tricks to reorient us, keeping our confusion to a minimum and quickly pointing us in the right direction. Research has suggested that animals and young children mainly rely on geometric cues (e.g. lengths, distances, angles) to help them get........Go to the Neurology news blog (Added on 1/12/2009 6:26:05 AM)
Insulin levels may have a say in breast cancer riskHigher-than-normal levels of insulin place postmenopausal women at increased risk of breast cancer, scientists at Albert Einstein College of Medicine of Yeshiva University report. Their findings, reported in the January 7 issue of the Journal of the National Cancer Institute, suggest that interventions that target insulin and its signaling pathways may decrease breast cancer risk in these women.
Breast cancer is the most common cancer........Go to the Breast-cancer-blog (Added on 1/12/2009 6:24:10 AM)
New evidence for warburg theory of cancerGerman scientist Otto H. Warburg's theory on the origin of cancer earned him the Nobel Prize in 1931, but the biochemical basis for his theory remained elusive.
His theory that cancer starts from irreversible injury to cellular respiration eventually fell out of favor amid research pointing to genomic mutations as the cause of uncontrolled cell growth.
Seventy-eight years after Warburg received science's highest honor, scientists from........Go to the Cancer-blog (Added on 1/12/2009 6:14:41 AM)
Hormone therapy and colorectal cancerThe combination of estrogen plus progestin, which women stopped taking in droves following the news that it may increase their risk of breast cancer, may decrease their risk of colorectal cancer, as per a report reported in the recent issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.
"In comparison to women who had never taken these hormones, the use of estrogen plus progestin........Go to the Colon-cancer-blog (Added on 1/8/2009 10:11:41 PM)
Help for the overweight over the phoneCounselling via the phone and internet can help weight management in overweight individuals, as per a Dutch study reported in the open access journal, BMC Public Health
The project compared counselling via phone and e-mail with the standard practice of issuing self-help literature in approximately 1400 workers as an aid to weight management. The study was undertaken by a group led by Willem Van Mechelen of the Department of Public and........Go to the Weight watcher's blog (Added on 1/8/2009 9:58:53 PM)
Experiences of older peopleIt's debilitating, isolating and can lead to severe depression - yet pain is widely accepted as something to be expected and regarded as 'normal' in later life.
Now a newly released study from The University of Nottingham examines older people's experiences of pain and how best Government, the NHS and social care agencies can address the issue.
The report, Pain in older people: reflections and experiences from an older person's........Go to the Society medical news blog (Added on 1/8/2009 9:51:31 PM)
Obesity starts in the head?Joint press release by the Helmholtz Zentrum München and the German National Genome Research Network.
Neuherberg, 2008-01-08. Obesity is known to increase the risk of chronic disorders, such as diabetes (type 2). An international team of researchers with German participation through the Helmholtz Zentrum München identified six new obesity genes. Gene expression analyses have shown that all six genes are active in brain cells.
The........Go to the Weight watcher's blog (Added on 1/8/2009 9:42:12 PM)
New class of antibioticsAs bacteria resistant to usually used antibiotics continue to increase in number, researchers keep searching for new sources of drugs. In this week's JBC, one potential new bactericide has been found in the tiny freshwater animal Hydra.
The protein identified by Joachim Grtzinger, Thomas Bosch and his colleagues at the University of Kiel, hydramacin-1, is unusual (and also clinically valuable) as it shares virtually no similarity with any........Go to the Infectious disease blog (Added on 1/15/2009 6:26:15 PM)
Telephone support after traffic accidentsPeople who were injured in road accidents had fewer problems and a much higher quality of life if they received a simple follow-up call from a nurse three weeks after being discharged from hospital, as per research in the recent issue of the Journal of Clinical Nursing
During the two-year study, scientists from Umea University in Sweden followed up 568 car occupants, cyclists and pedestrians who had attended the same emergency department........Go to the Psychology news blog (Added on 1/14/2009 11:40:35 PM)
Can coffee drinking increase risk of dementia?Stockholm, Sweden -- Midlife coffee drinking can decrease the risk of dementia/Alzheimer's disease (AD) during the later part of life. This conclusion is made in a Finnish Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Study reported in the January 2009 issue of the Journal of Alzheimer's Disease (Volume 16:1).
This study has been conducted at the University of Kuopio, Finland in collaboration with Karolinska Institutet, Stockholm,........Go to the Psychology news blog (Added on 1/14/2009 11:38:30 PM)
Obesity may lead to complications at surgeryA newly reported study in the recent issue of the Journal of the American College of Surgeons shows that morbidly obese patients are at higher risk than normal weight patients for complications after colectomy surgical removal of all or part of the colon for the therapy of cancer.
Obese patients are more likely than non-obese patients to develop and ultimately die from colon cancer, the second leading cause of cancer death in the United........Go to the Weight watcher's blog (Added on 1/14/2009 11:16:46 PM)
Exercise, mood and grievous psychological problemsA newly released study from Indiana University suggests that even meager levels of physical activity can improve the mood of people with serious mental illnesses (SMI) such as bipolar disorder, major depression and schizophrenia.
The study, reported in the recent issue of the "International Journal of Social Psychiatry," both reinforces earlier findings that people with SMI demonstrate low levels of physical activity and supports the........Go to the Weight watcher's blog (Added on 1/14/2009 9:29:37 PM)
Hepatitis C May Increase Pancreatic Cancer RiskA newly released study shows that infection with hepatitis C virus (HCV) increases a person's risk for a highly fatal cancer of the biliary tree, the bile carrying pathway between the liver and pancreas. This finding is in the recent issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience........Go to the GI news blog (Added on 1/14/2009 6:27:26 AM)
You are Not What your Mother EatsScientists S. Stanley Young, Ph.D., Assistant Director of the National Institute of Statistical Sciences, Heejung Bang, Ph.D., of Cornell University and Kutluk Oktay. MD, FACOG, Professor of Obstetrics & Gynecology and Director, Division of Reproductive Medicine & Infertility Department of Obstetrics & Gynecology from New York Medical College, wrote a paper, "Cereal-Induced Gender Selection? Most Likely a Multiple Testing False Positive," which........Go to the OBGYN news blog (Added on 1/14/2009 6:07:21 AM)
Physically active lifestyle is just a few clicks away New research suggests that a healthier, more physically active lifestyle is just a few clicks away with Dairy Council of California's MyFitness Planner.
Regular physical activity can reduce the risk of chronic diseases like type 2 diabetes, heart disease and cancer, yet less than half of all American women (47.7 percent) engage in at least 30 minutes of moderate-intensity or greater physical activity on most days of the week. To help, Dairy........Go to the Weight watcher's blog (Added on 1/13/2009 11:37:12 PM)
Diabetes dementia and brain injuriesPatients with dementia and diabetes appear to display a different pattern of injuries in their brains than patients with dementia but without diabetes, as per an article posted online today that will appear in the March print issue of Archives of Neurology, one of the JAMA/Archives journals.
"The association between diabetes mellitus and increased risk for dementia in the elderly is well documented," the authors write as background........Go to the Diabetes-watch-blog (Added on 1/12/2009 11:49:47 PM)
A switchboard in the brain helps us learn and rememberThe healthy brain is in a constant struggle between learning new experiences and remembering old experiences, a newly released study in this week's PLoS Biology reports. Virtually all social interactions require the rapid exchange of new and old information. For instance, normal conversation requires that while listening to the new information another person is providing, we are already retrieving information in preparation of an appropriate........Go to the Neurology news blog (Added on 1/12/2009 11:45:06 PM)
New weapon in battle against HIV infection?Scientists have discovered a potentially important new resistance factor in the battle against HIV: blood types. An international team of scientists from Canadian Blood Services, The Hospital for Sick Children (SickKids) and Lund University in Sweden have discovered that certain blood types are more predisposed to contracting HIV, while others are more effective at fending it off.
A carbohydrate-containing antigen, termed Pk blood group........Go to the Infectious disease blog (Added on 1/12/2009 11:40:54 PM)
New Clues To Understanding CancerIn the 13th January print edition of the journal Current Biology, Instituto Gubenkian de Ciencia scientists provide insight into an old mystery in cell biology, and offer up new clues to understanding cancer. Ins Cunha Ferreira and Mnica Bettencourt Dias, working with scientists at the universities of Cambridge, UK, and Siena, Italy, unravelled the mystery of how cells count the number of centrosomes, the structure that regulates the cell's........Go to the Cancer-blog (Added on 1/12/2009 11:32:17 PM)
Epidural anesthesia is safeThe largest ever prospective study [1,2] into the major complications  of epidurals and spinal anaesthetics reported in the British Journal of Anaesthesia today (Monday 12 January 2009) concludes that prior studies have over-estimated the risks of severe complications of these procedures. The study concludes that the estimated risk of permanent harm following a spinal anaesthetic or epidural is lower than 1 in 20,000 and in a number of........Go to the OBGYN news blog (Added on 1/12/2009 6:42:29 PM)
Fighting cholesterol with synthetic HDL Buttery Christmas cookies, eggnog, juicy beef roast, rich gravy and creamy New York-style cheesecake. Happy holiday food unfortunately can send blood cholesterol levels sky high.
Northwestern University researchers now offer a promising new weapon -- synthetic high-density lipoprotein (HDL), the "good" cholesterol -- that could help fight chronically high cholesterol levels and the deadly heart disease that often results.
The scientists........Go to the Heart-watch-blog (Added on 1/12/2009 6:28:24 AM)
New genes that fuse in cancerUsing new technologies that make it easier to sequence the human genome, scientists at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade places with each other. These recurrent gene fusions are believed to be the driving mechanism that causes certain cancers to develop.
The gene fusions discovered could potentially serve as a marker one day for diagnosing........Go to the Cancer-blog (Added on 1/12/2009 6:19:21 AM)
Without becoming obeseBerkeley -- Scientists at the University of California, Berkeley, have identified a new enzyme that plays a far more important role than expected in controlling the breakdown of fat. In a newly released study would be published Jan. 11 in the journal Nature Medicine, scientists report that mice that have had this enzyme disabled remained lean despite eating a high-fat diet and losing a hormone that suppresses appetite.
"We have discovered a........Go to the Weight watcher's blog (Added on 1/12/2009 6:17:09 AM)
Surprisingly high tolerance for racismWhite people do not get as upset when confronted with racial prejudice as they think they will, a study by scientists at Yale University, York University, and the University of British Columbia suggests. This indifference helps explains why racism persists even as the United States prepares to celebrate the inauguration of Barack Obama, scientists say.
Non-black participants who experienced a racial slur against a black person did not get as........Go to the Society medical news blog (Added on 1/8/2009 10:06:35 PM)
Cancer prevention properties of black raspberriesA study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, identifies components of black raspberries with chemopreventive potential.
Scientists at the Ohio State Comprehensive Cancer Center observed that anthocyanins, a class of flavonoids in black raspberries, inhibited growth and stimulated apoptosis in the esophagus of rats treated with an esophageal carcinogen.
"Our data provide good........Go to the Cancer-blog (Added on 1/8/2009 10:04:49 PM)
Behavioral difficulties at schoolAdolescents who misbehave at school are more likely to have difficulties throughout their adult lives, finds a 40-year study of British citizens published on bmj.com today. These difficulties cover all areas of life, from mental health to domestic and personal relationships to economic deprivation.
Severe behavioural problems in schools affect about 7% of 9-15 year olds and have been on the increase for the past 30 years. Prior studies have........Go to the Society medical news blog (Added on 1/8/2009 9:53:53 PM)
Women's brains recognize smell of male sexual sweatA new Rice University study reported in the Journal of Neuroscience observed that socioemotional meanings, including sexual ones, are conveyed in human sweat.
Denise Chen, assistant professor of psychology at Rice, looked at how the brains of female volunteers processed and encoded the smell of sexual sweat from men.
The results of the experiment indicated the brain recognizes chemosensory communication, including human sexual sweat.
........Go to the Society medical news blog (Added on 1/8/2009 9:47:49 PM)