Teaching old drugs new tricksScientists from the European Molecular Biology Laboratory (EMBL) discovered a new way to make use of drugs' unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target molecule. The study, published in Science this week, hints at new uses of marketed drugs.
Similar drugs often share target proteins, modes of action and........Go to the Research news blog (Added on 7/10/2008 9:45:44 PM)
New discovery could lead to an improved influenza vaccineFindings just reported in the scientific journal Immunity by scientists at the Trudeau Institute shed new light on how a previously-unknown messaging mechanism within the human immune system prompts specific influenza-fighting cells to the lung airways during an infection.
Infections from the influenza virus are responsible for hundreds of thousands of hospitalizations and as a number of as 40,000 deaths in the United States each year.........Go to the Infectious disease blog (Added on 7/10/2008 8:43:03 PM)
A short and sweet diagnosis for cancer?In order to provide the most effective therapys for cancer patients, it is essential to develop methods of sensitive and specific early detection of the disease. A team of researchers from the NIBRT Dublin-Oxford Glycobiology Laboratory at UCD has developed a system which aims to pinpoint potential "biomarkers" of early forms of the disease. They do this by looking at the structures of specific sugar molecules which are attached either to........Go to the Cancer-blog (Added on 7/9/2008 9:13:33 PM)
Ionophore reverses Alzheimer's within daysResearchers report a remarkable improvement in Alzheimer's transgenic mice following therapy with a new drug. The study, published by Cell Press in the July 10th issue of the journal Neuron, provides the first demonstration that an ionophore, a compound that transports metal ions across cell membranes, can elicit rapid and pronounced improvement in neuropathology and cognitive function in mouse models of Alzheimer's Disease (AD).
Recent........Go to the Neurology news blog (Added on 7/9/2008 8:59:35 PM)
Vaccinated infants are well protectedIn 2006, a pneumococcal vaccine (Prevenar®) was introduced in the childhood vaccination programme in Norway. Two years later, the experiences have been reported in the journal Vaccine. The results show a strong decline in serious pneumococcal infections among young children.
Pneumococcus is a bacterium that can cause serious illnesses in some young children, e.g. meningitis, blood poisoning and pneumonia. Most of those who become ill are........Go to the Pediatric news blog (Added on 7/9/2008 7:32:57 PM)
Predicting birthweights in obese mothersScientists have found what they believe to be the most accurate way of predicting the birth-weight of babies born to the growing number of obese mothers, as per a research studyin the UK-based journal Ultrasound in Obstetrics and Gynecology
Experts from the University of Rochester Strong Memorial Hospital in Rochester, New York, USA, have recorded accurate results in more than nine out of ten cases using the gestation-adjusted projection........Go to the OBGYN news blog (Added on 7/9/2008 7:30:12 PM)
Study points to cocktail therapy for Alzheimer'sA dietary cocktail that includes a type of omega-3 fatty acid can improve memory and learning in gerbils, as per the latest study from MIT scientists that points to a possible beverage-based therapy for Alzheimer's and other brain diseases.
The combination of supplements, which contains three compounds normally found in the bloodstream, is now being tested in Alzheimer's patients. The cocktail has previously been shown to promote growth of........Go to the Neurology news blog (Added on 7/8/2008 9:00:28 PM)
Young women's breast cancers have more aggressive genesYoung women's breast cancers tend to be more aggressive and less responsive to therapy than the cancers that arise in older women, and scientists at the Duke Comprehensive Cancer Center and the Duke Institute for Genome Sciences & Policy may have discovered part of the reason why: young women's breast cancers share unique genomic traits that the cancers in older women do not exhibit.
"Clinicians have long noted that the breast cancers we see........Go to the Breast-cancer-blog (Added on 7/8/2008 8:49:01 PM)
Higher education and mortality reduction from cancersDeaths due to the four most common cancerslung, colorectal, prostate, and breasthave dropped substantially in the United States from 1993 to 2001 in working-aged individuals. However, not all Americans are equally likely to benefit from those gains. A study reported in the July 8 online issue of the Journal of the National Cancer Institute shows that more highly educated individuals had mortality reductions in nearly all of these cancers, while........Go to the Cancer-blog (Added on 7/8/2008 8:44:11 PM)
Insect warning colors aid cancer drug discoveryBrightly colored beetles or butterfly larvae nibbling on a plant may signal the presence of chemical compounds active against cancer cell lines and tropical parasitic diseases, as per scientists at Smithsonian's Tropical Research Institute in Panama. Such clues could speed drug discovery and provide insight into the ecological relationships between tropical-forest plants and insects that feed on them. The report is reported in the Ecological........Go to the Cancer-blog (Added on 7/8/2008 6:38:12 PM)
Can recycling be used to treat cancer?We already know that recycling benefits our planet; and now new research suggests that the cellular version might be useful for battling cancer. Researchers at Stanford University have identified a molecule that uses this unexpected pathway to selectively kill cancer cells. The research, published by Cell Press in the July 8th issue of the journal Cancer Cell, may drive therapy strategies for cancer in an entirely new direction.
Renal cell........Go to the Cancer-blog (Added on 7/7/2008 9:56:29 PM)
PTSD causes early death from heart diseaseVietnam veterans who experienced posttraumatic stress disorder (PTSD) were twice as likely to die from heart disease as veterans without PTSD, a new Geisinger study finds.
As per a research findings reported in the recent issue of Psychosomatic Medicine, Geisinger Senior Investigator Joseph Boscarino, PhD, MPH examined the prevalence of heart disease, PTSD and other problems in more than 4,000 Vietnam veterans.
The more severe the PTSD........Go to the Psychology news blog (Added on 7/7/2008 9:50:10 PM)
Pregnancy and risk of heart attackEventhough acute myocardial infarction (AMI) is rare in women of child-bearing age, pregnancy can increase a woman's risk of heart attack 3- to 4-fold, as per a research studyreported in the July 15, 2008, issue of the Journal of the American College of Cardiology Since women today may delay having children until during the later part of life, and advances in reproductive medicine enable older women to conceive, the occurrence of AMI linked to........Go to the OBGYN news blog (Added on 7/7/2008 9:34:25 PM)
Child care factors associated with weight gain in infancyNine-month-old infants regularly cared for by someone other than a parent appear to have higher rates of unfavorable feeding practices and to weigh more than infants cared for only by parents, as per a report in the recent issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Almost three-fourths of infants receive some form of child care by persons who are not their parents during the first year of life,........Go to the Pediatric news blog (Added on 7/7/2008 9:16:27 PM)
Malaria on the increase in the UKA huge rise in the numbers of UK residents travelling to malaria endemic areas, combined with a failure to use prevention measures, has significantly increased cases of imported falciparum malaria in the UK over the past 20 years, as per a research studypublished on BMJ.com.
Between 1987 there were 5120 reported cases of the potentially fatal faliciparum malaria, increasing to 6753 in 2002. These findings........Go to the Infectious disease blog (Added on 7/3/2008 9:09:06 PM)
Disclosing violence to primary care or obestetricsScientists from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) observed that patients who disclose intimate partner violence (IPV) to their clinicians of any type did not experience serious harm. However, those who disclosed IPV in a primary care or obstetrics/gynecology setting received the most benefit. The findings, which appear in the Biomedical Central Public Health Journal, also conclude that disclosures made........Go to the Psychology news blog (Added on 7/3/2008 8:55:45 PM)
Healthy or diseased?Researchers from the Institute for Bioinformatics and Systemic Biology of the Helmholtz Zentrum München and the Faculty for Biology of the Ludwig-Maximilians-Universität have shown that biological indicators for diseases caused or influenced by environmental factors can be detected by the systemic analysis of the body's metabolism (metabolomics). The procedure presented here is also suitable for pre-clinical drug testing and allows for the........Go to the Society medical news blog (Added on 7/2/2008 10:35:35 PM)
Weight Watchers Versus Fitness CentersIn the first study of its kind, using sophisticated methods to measure body composition, the nationally known commercial weight loss program, Weight Watchers, was in comparison to gym membership programs to find out which method wins in the game of good health. A University of Missouri researcher examined the real-life experiences of participants to determine which program helps people lose pounds, reduce body fat and gain health benefits. The........Go to the Weight watcher's blog (Added on 7/2/2008 10:29:56 PM)
Computers to hone cancer-fighting strategiesA Florida State University faculty member who uses computational techniques to evaluate a new class of cancer-killing drugs is attracting worldwide attention from other researchers.
Kevin C. Chen, an assistant professor of chemical and biomedical engineering at the Florida A&M University-Florida State University College of Engineering, is using high-powered computers to determine how substances known as recombinant immunotoxins can best be........Go to the Cancer-blog (Added on 7/2/2008 10:10:57 PM)
Get smart about what you eat to improve your intelligenceNew research findings published online in The FASEB Journal provide more evidence that if we get smart about what we eat, our intelligence can improve. As per MIT scientists, dietary nutrients found in a wide range of foods from infant formula to eggs increase brain synapses and improve cognitive abilities.
"I hope human brains will, like those of experimental animals, respond to this kind of therapy by making more brain synapses and thus........Go to the Weight watcher's blog (Added on 7/2/2008 10:07:41 PM)
Prostate cancer vaccines more effective with hormone therapyAmong patients with castration-resistant prostate cancer, the addition of hormone treatment following vaccine therapy improved overall survival compared with either therapy alone or when the vaccine followed hormone therapy, as per recent data reported in the July 15 Clinical Cancer Research, a journal of the American Association for Cancer Research.
Philip M. Arlen, M.D., director of the Clinical Research Group for the Laboratory of Tumor........Go to the Prostate-cancer-blog (Added on 7/10/2008 9:43:45 PM)
Link shown between thunderstorms and asthma attacksIn the first in-depth study of its kind ever done in the Southeastern United States, scientists at the University of Georgia and Emory University have discovered a link between thunderstorms and asthma attacks in the metro Atlanta area that could have a "significant public health impact".
While a relationship between thunderstorms and increased hospital visits for asthma attacks has been known and studied worldwide for years, this is the........Go to the Allergy news blog (Added on 7/10/2008 8:33:58 PM)
How food affects the brainIn addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders.
"Food is like a pharmaceutical compound that affects the brain," said Fernando Gmez-Pinilla, a UCLA professor of neurosurgery and physiological science who has spent years studying the effects of food, exercise and sleep on the brain. "Diet, exercise and sleep have the potential to........Go to the Weight watcher's blog (Added on 7/9/2008 9:16:35 PM)
The Internet, alcohol and sleepGirls moving through adolescence may experience unhealthy levels of weight gain, but the reasons for this are not always clear. In fact, a number of potential causes of weight gain are easily overlooked. A new study soon would be published in The Journal of Pediatrics analyzes the effect of Internet usage, sleep, and alcohol and coffee consumption on weight gain in adolescent girls.
Dr. Catherine Berkey and his colleagues from Harvard........Go to the Psychology news blog (Added on 7/9/2008 9:08:04 PM)
Obese men have less semen, more sperm abnormalitiesObese men should consider losing weight if they want to have children, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday 9 July). Dr. A Ghiyath Shayeb, from the University of Aberdeen, Aberdeen, UK, said that his research had shown that men with a higher body mass index (BMI) had lower volumes of seminal fluid and a higher proportion of abnormal sperm.
Dr. Shayeb and his........Go to the Weight watcher's blog (Added on 7/9/2008 7:37:45 PM)
Herceptin targets breast cancer stem cellsA gene that is overexpressed in 20 percent of breast cancers increases the number of cancer stem cells, the cells that fuel a tumor's growth and spread, as per a new study from the University of Michigan Comprehensive Cancer Center.
The gene, HER2, causes cancer stem cells to multiply and spread, explaining why HER2 has been associated with a more aggressive type of breast cancer and to metastatic disease, in which the cancer has spread........Go to the Breast-cancer-blog (Added on 7/9/2008 7:27:31 PM)
The association with stress and depressionThe brain is the key organ in the response to stress. Brain reactions determine what in the world is threatening and might be stressful for us, and regulate the stress responses that can be either adaptive or maladaptive. Chronic stress can affect the brain and lead into depression: Environmental stressors correlation to job or family situation are important triggers of depressive episodes and major life events such as trauma or abuse amongst........Go to the Psychology news blog (Added on 7/8/2008 9:02:44 PM)
Keeping a food diary doubles diet weight lossKeeping a food diary can double a person's weight loss as per a research studyfrom Kaiser Permanente's Center for Health Research. The findings, from one of the largest and longest running weight loss maintenance trials ever conducted, would be reported in the recent issue of the American Journal of Preventive Medicine
Funded by the National Heart, Lung and Blood Institute at the National Institutes of Health, the study is one of the few........Go to the Weight watcher's blog (Added on 7/8/2008 8:50:41 PM)
How the malaria parasite hijacks human red blood cellsA new studydone on a scale an order of magnitude greater than anything previously attempted in the field of malariahas uncovered an arsenal of proteins produced by the malaria parasite that allows it to hijack and remodel human red blood cells, leaving the oxygen-carrying cells stiff and sticky. Those effects on the blood cells play a major role in the development of malaria, a disease responsible for millions of deaths every year, the........Go to the Infectious disease blog (Added on 7/8/2008 8:28:50 PM)
Schizophrenia linked to dysfunction in molecular brain pathwayAlterations in a molecular brain pathway activated by marijuana may contribute to the cognitive symptoms of schizophrenia, as per a report in the recent issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Expression of the cannabinoid 1 receptor (CB1R), the site of action of the main chemical ingredient of marijuana, is significantly reduced in the brains of individuals with schizophrenia. Activation of CB1R impairs........Go to the Psychology news blog (Added on 7/7/2008 10:07:39 PM)
A baby's smile is a natural highThe baby's smile that gladdens a mother's heart also lights up the reward centers of her brain, said Baylor College of Medicine scientists in a report that appears in the journal Pediatrics today.
The finding could help researchers figure out the special mother-infant bond and how it sometimes go wrong, said Dr. Lane Strathearn, assistant professor of pediatrics at BCM and Texas Children's Hospital and a research associate in BCM's Human........Go to the Pediatric news blog (Added on 7/7/2008 9:58:23 PM)
Newborn vitamin A reduces infant mortalityA single, oral dose of vitamin A, given to infants shortly after birth in the developing world can reduce their risk of death by 15 percent, as per a research studyconducted by scientists at the Johns Hopkins Bloomberg School of Public Health. The study is reported in the July 2008 edition of the journal Pediatrics
"It has long been known that vitamin A supplementation can reduce mortality in children over 6 months of age. Our study showed........Go to the Pediatric news blog (Added on 7/7/2008 9:43:11 PM)
Combination drug taken early relieves migraine symptoms A combination drug taken within an hour after the start of a migraine is effective in relieving symptoms, as per research reported in the July 8, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.
The drug combines sumatriptan, a migraine-specific drug that affects the constriction of blood vessels, with naproxen sodium, a non-steroidal anti-inflammatory drug that works on the inflammatory aspect of migraine........Go to the Neurology news blog (Added on 7/7/2008 9:37:53 PM)
Red wine ingredient wards off effects of age on heartLarge doses of a red wine ingredient can ward off a number of of the vagaries of aging in mice who begin taking it at midlife, as per a new report published online on July 3rd in Cell Metabolism, a Cell Press publication. Those health improvements of the chemical known as resveratrolincluding cardiovascular benefits, greater motor coordination, reduced cataracts and better bone densitycome without necessarily extending the animals' lifespan.
........Go to the Heart-watch-blog (Added on 7/3/2008 9:11:17 PM)
Statins have unexpected effect on brain cellsCholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, researchers at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.
Neuroresearchers observed that statins, one of the most widely prescribed classes of medicine ever used, have an unexpected effect on brain cells.........Go to the Heart-watch-blog (Added on 7/3/2008 9:03:50 PM)
Woman aquires new accent after strokeA woman in southern Ontario is one of the first cases in Canada of a rare neurological syndrome in which a person starts speaking with a different accent, McMaster University scientists report in the recent issue of the Canadian Journal of Neurological Sciences
The puzzling medical phenomenon known as foreign-accent syndrome (FAS) arises from neurological damage, and results in vocal distortions that typically sound like the speaker has a........Go to the Neurology news blog (Added on 7/3/2008 9:01:44 PM)
ETH Zurich and IBM improve diagnosis of osteoporosisWith the goal of developing an accurate, powerful and fast method to automate the analysis of bone strength, researchers of the ETH Zurich Departments of Mechanical and Process Engineering and Computer Science teamed up with supercomputing experts at IBM's Zurich Research Laboratory. The breakthrough method developed by the team combines density measurements with a large-scale mechanical analysis of the inner-bone microstructure.
Using........Go to the Society medical news blog (Added on 7/2/2008 10:38:16 PM)
MRSA carrier state increases risk of infectionPatients harboring methicillin-resistant Staphylococcus aureus (MRSA) for long periods of time continue to be at increased risk of MRSA infection and death, as per a new study in the July 15 issue of Clinical Infectious Diseases, currently available online.
MRSA is an antibiotic-resistant bacterium that can cause a variety of serious infections. The bacterium most usually colonizes the nostrils, eventhough it can be found in other body........Go to the Infectious disease blog (Added on 7/2/2008 10:24:06 PM)
New Drug Candidates to Combat "Bird Flu"As the specter of a worldwide outbreak of avian or "bird flu" lingers, health officials recognize that new drugs are desperately needed since some strains of the virus already have developed resistance to the current roster of anti-flu remedies.
Now, a team of UC San Diego researchers - with the help of resources at the San Diego Supercomputer Center (SDSC), also at UC San Diego - have isolated more than two dozen promising and novel........Go to the Research news blog (Added on 7/2/2008 10:16:22 PM)
Minimum drinking age of 21 saves livesOne of the most comprehensive studies on the minimum drinking age shows that laws aimed at preventing consumption of alcohol by those under 21 have significantly reduced drinking-related fatal car crashes.
Specifically, the study reported in the July 2008 issue of the journal Accident Analysis and Prevention observed that laws making it illegal to possess or purchase alcohol by anyone under the age of 21 had led to an eleven percent drop in........Go to the Psychology news blog (Added on 7/1/2008 9:44:38 PM)