Cutting carbs is more effective than low-fat dietObese women with insulin resistance lose more weight after three months on a lower-carbohydrate diet than on a traditional low-fat diet with the same number of calories, as per a newly released study. The results will be presented Saturday at The Endocrine Society's 92nd Annual Meeting in San Diego.
"The typical diet that physicians recommend for weight loss is a low-fat diet," said the study's main author, Raymond Plodkowski, MD, chief of........Go to the Diabetic news blog (Added on 6/21/2010 7:16:34 AM)
New strategy to fight cancer drug resistanceResearchers at Dana-Farber Cancer Institute have found a way to disable a common protein that often thwarts chemotherapy therapy of several major forms of cancer.
The scientists discovered, surprisingly, that they could exploit a small portion of this anti-death protein, called MCL-1, to make a molecular tool that specifically blocked MCL-1's "pro-survival" action, allowing standard cancer drugs to kill the tumor cells by apoptosis, or........Go to the Cancer-blog (Added on 6/21/2010 7:14:02 AM)
Early detection of ovarian cancerDespite a number of research advances, ovary cancer remains lethal in a majority of cases, due to late diagnosis of the disease. In a newly released study, Dr. Joshua LaBaer of the Biodesign Institute at Arizona State University, along with Arturo Ramirez and Paul Lampe, scientists at the Fred Hutchinson Cancer Research Center in Seattle, used a novel method for identifying biomarkers-proteins in blood that can identify ovary cancer before........Go to the Ovarian cancer blog (Added on 6/17/2010 7:23:09 AM)
Mediterranean-style diet improves heart functionA study of twins shows that even with genes that put them at higher risk of cardiovascular disease, eating a Mediterranean-style diet can improve heart function, as per research reported in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.
Using data from the Emory Twins Heart Study, scientists observed that men eating a Mediterranean-style diet had greater heart rate variability (HRV) than those eating........Go to the Heart-watch-blog (Added on 6/16/2010 7:26:42 AM)
Personalized treatment for melanomaIdentification of a key player in a signaling pathway involved in the development of melanoma the deadliest form of skin cancer may offer hope for new targeted melanoma therapies.
Ann Richmond, Ph.D., and his colleagues at Vanderbilt-Ingram Cancer Center report that a signaling molecule, known as IKKβ, is essential for melanoma tumor development in a mouse model of the disease. The results, published June 7 in the Journal of Clinical........Go to the Cancer-blog (Added on 6/16/2010 7:22:32 AM)
Alcohol effect on fetal development It's long been known that alcohol use in pregnancy can lead to children with mental retardation and birth defects, but scientists who study fetal alcohol syndrome (FAS) have not made definitive progress on preventing the disorder, detecting it early, or effectively treating it, say scientists from Georgetown University Medical Center.
In the issue of Developmental Neuroscience, four first-year medical students at Georgetown University........Go to the OBGYN news blog (Added on 6/16/2010 7:20:21 AM)
link between IVF treatments and autism?The first "test tube baby" was born in 1978. With advances in reproductive science, an estimated one percent of all American babies are now born each year through in vitro fertilization (IVF). But IVF and other assisted fertility therapys appears to be solving one problem by creating another, suggests new evidence from Tel Aviv University.
In a recent study, Dr. Ditza Zachor of Tel Aviv University's Sackler School of Medicine reported a........Go to the OBGYN news blog (Added on 6/14/2010 10:22:43 PM)
Apple juice improves behavior in Alzheimer's patientsApple juice can be a useful supplement for calming the declining moods that are part of the normal progression of moderate-to-severe Alzheimer's Disease (AD), as per a research studyin American Journal of Alzheimer's Disease and Other Dementias (AJADD), published by SAGE.
In the AJADD study, after institutionalized AD patients consumed two 4-oz glasses of apple juice a day for a month, their caregivers reported no change in the patients'........Go to the Neurology news blog (Added on 6/14/2010 10:13:29 PM)
Chemotherapy of Late-stage ovarian cancerThe combination of decitabine and carboplatin appears to improve the outcome of women who have late-stage ovary cancer. In an upcoming issue of the journal Cancer (online today), Indiana University scientists report four of 10 patients who participated in a phase I clinical trial had no disease progression after six months of therapy. One patient experienced complete resolution of tumor tissue for a period of time.
Advanced ovary cancer is........Go to the Ovarian cancer blog (Added on 6/9/2010 11:22:08 PM)
Depression and Abdominal ObesityA newly released study at the University of Alabama at Birmingham (UAB) confirms the relationship between depression and abdominal obesity, which has been associated with an increased risk for cancer and cardiovascular disease.
"We observed that in a sample of young adults during a 15-year period, those who started out reporting high levels of depression gained weight at a faster rate than others in the study, but starting out overweight did........Go to the Weight watcher's blog (Added on 6/9/2010 10:59:47 PM)
Healthy diet could slow Alzheimer's diseasePatients in the early to moderate stages of Alzheimer's Disease could have their cognitive impairment slowed or even reversed by switching to a healthier diet, as per scientists at Temple University.
In a prior study, scientists led by Domenico Pratic, an associate professor of pharmacology in Temple's School of Medicine, demonstrated that a diet rich in methionine could........Go to the Neurology news blog (Added on 6/9/2010 6:51:14 AM)
Income, race link for kidney diseaseAfrican Americans with incomes below the poverty line have a significantly higher risk of chronic kidney disease (CKD) than higher-income African-Americans or whites of any socioeconomic status, research led by researchers at Johns Hopkins and the National Institute on Aging shows. Conducted in a racially and socioeconomically diverse sample of participants from the city of Baltimore, Md., the study could help scientists eventually develop........Go to the Kidney watch blog (Added on 6/9/2010 6:44:18 AM)
Updated HIV therapy guidelinesScientists from the BC Centre for Excellence in HIV/AIDS (BC-CfE) and the University of British Columbia today released a comprehensive study revealing that the 2008 IAS-USA treatment guidelines for commencing HIV therapy would create significant benefits for individuals infected with HIV and society as a whole.
The peer-evaluated mathematical modeling study, reported in the research journal PLoS ONE, shows that full implementation of HIV........Go to the Infectious disease blog (Added on 6/8/2010 6:46:49 AM)
Getting extra sleep improves the athletic performanceGetting extra sleep over an extended period of time improves athletic performance, alertness and mood, as per a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.
Results indicate that football players' sprint times improved significantly after seven to eight weeks of sleep extension. Average sprint time in the........Go to the Weight watcher's blog (Added on 6/8/2010 6:38:15 AM)
Potential genetic factor in eating disordersFor the first time, researchers have discovered a possible biological culprit in the development of eating disorders during puberty: a type of estrogen called estradiol.
The groundbreaking pilot study led by Michigan State University observed that influence of one's genes on eating disorder symptoms was much greater in pubertal girls with higher levels of estradiol than pubertal girls with lower levels of estradiol. The study appears in the........Go to the Weight watcher's blog (Added on 6/7/2010 6:51:29 AM)
How smarter school lunchrooms increase fruit salesHow a number of more apples can a school cafeteria sell if the fruit is displayed in an attractive basket and placed in a well-lit area? .
That's the sort of question scientists from the Cornell Food and Brand Lab are exploring as part of their Smarter Lunchrooms Initiativean effort to discover and share low-cost changes that can be made in lunchrooms to subtly guide smarter food choices.
Led by Professor Brian Wansink, the scientists........Go to the Society medical news blog (Added on 6/7/2010 6:48:06 AM)
Alcohol use and smoking may cause headacheA novel study by German scientists reported that alcohol consumption and cigarette smoking were linked to increased migraines and tension-type headaches (TTH) in high school students. Coffee drinking and physical inactivity were associated specifically with migraines. Results of this study, the first to investigate modifiable risk factors for different types of headaches in a youth population, appear online early in Headache, a journal........Go to the Society medical news blog (Added on 6/7/2010 6:34:12 AM)
Selenium shows no benefitSelenium, a supplement taken daily by millions in hopes of protection against cancer and a host of other diseases, has proven to be of no benefit in reducing a patient's risk of developing lung cancer - either a recurrence or second primary malignancy, as per results of an international Phase III clinical trial.
Results from the decade-long study, initiated by the Eastern Cooperative Oncology Group, were presented today at the American........Go to the Lung-cancer-blog (Added on 6/6/2010 8:48:58 PM)
Dasatanib: CML drug evokes faster responseDasatanib, a medicine currently approved as therapy for drug-resistant chronic myeloid leukemia (CML), provided patients with quicker, better responses as a first treatment than the existing front-line drug, as per scientists at The University of Texas MD Anderson Cancer Center.
The findings were presented at the 46th Annual Meeting of the American Society of Clinical Oncology today, and reported in the New England Journal (NEJM) Hagop........Go to the Cancer-blog (Added on 6/6/2010 8:47:20 PM)
Remote control for cholesterol regulationCirculation of cholesterol is regulated in the brain by the hunger-signaling hormone ghrelin, scientists say. The finding points to a new potential target for the pharmacologic control of cholesterol levels.
The animal study, led by Matthias Tschp, MD, professor in the University of Cincinnati (UC) endocrinology division, appears online ahead of print Sunday, June 6, 2010, in Nature Neuroscience
"We have long thought that cholesterol is........Go to the Heart-watch-blog (Added on 6/6/2010 8:39:32 PM)
Certain obese people are not at high risk of heart diseaseObese people without metabolic risk factors for diabetes and heart disease, such as hypertension and cholesterol, do not have the elevated cardiovascular risk typical of obesity, but they represent only a small percentage of the obese population, as per a long-term study. The results will be presented Saturday at The Endocrine Society's 92nd Annual Meeting in San Diego.
"Some obese persons have a normal cardiovascular risk profile, and they........Go to the Heart-watch-blog (Added on 6/21/2010 7:15:28 AM)
Risk of heart attack in Rheumatoid Arthritis patientsRheumatoid Arthritis (RA) patients face a two hundred percent increased risk of suffering a Myocardial Infarction (MI, heart attack) versus the general population, which is comparable to the increased risk of MI seen in diabetes patients, as per results of a newly released study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.
In this Danish, nationwide, 10 year study, RA and........Go to the Rheumatology news blog (Added on 6/18/2010 6:48:16 AM)
Vitamin D deficiency and rheumatic conditionsTwo separate studies have shown that vitamin D deficiency is common in patients with a range of rheumatic diseases, with over half of all patients having below the 'normal' healthy levels of vitamin D (48-145 nmol/L) in their bodies. A further study assessing response to vitamin D supplementation observed that taking the recommended daily dose did not normalise vitamin D levels in rheumatic disease patients. The results of these three studies........Go to the Rheumatology news blog (Added on 6/18/2010 6:46:40 AM)
Remission during pregnancy?During pregnancy, a number of women experience remission of autoimmune diseases like multiple sclerosis and uveitis. Now, researchers have described a biological mechanism responsible for changes in the immune system that helps to explain the remission.
The expression of an enzyme known as pyruvate kinase is reduced in immune cells in pregnant women in comparison to non-pregnant women, as per Howard R. Petty, Ph.D., biophysicist at the........Go to the OBGYN news blog (Added on 6/17/2010 7:10:24 AM)
Linking diabetes and cancerA new consensus statement of experts assembled by the American Diabetes Association and the American Cancer Society reviews emerging evidence that suggests cancer incidence is linked to diabetes as well as certain diabetes risk factors and therapys. The new report reviews the state of science concerning the association between diabetes and cancer incidence/prognosis; risk factors common to both diseases; possible biologic links between diabetes........Go to the Cancer-blog (Added on 6/16/2010 7:21:37 AM)
How does that taste to you?Low-salt foods appears to be harder for some people to like than others, as per a research studyby a Penn State College of Agricultural Sciences food scientist. The research indicates that genetics influence some of the difference in the levels of salt we like to eat.
Those conclusions are important because recent, well-publicized efforts to reduce the salt content in food have left a number of people struggling to accept fare that simply........Go to the Society medical news blog (Added on 6/16/2010 7:19:03 AM)
Turning a painkiller into a cancer killerWithout knowing exactly why, researchers have long found that people who regularly take non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin have lower incidences of certain types of cancer. Now, in a study appearing in Cancer Cell on June 15, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) and their colleagues have figured out how one NSAID, called Sulindac, inhibits tumor growth. The study reveals that........Go to the Cancer-blog (Added on 6/14/2010 10:26:44 PM)
Predicting success with cancer drugsScientists at the Translational Genomics Research Institute (TGen), the Van Andel Research Institute (VARI) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare have discovered a biomarker that could help in the therapy of patients with an aggressive type of lung cancer.
Using a particular biomarker, scientists might better predict which patients with small cell lung cancer are resistant to existing drug therapies, and which ones........Go to the Lung-cancer-blog (Added on 6/14/2010 10:11:14 PM)
Cancer risks of blood pressure medicationsUniversity Hospitals Case Medical Center heart specialists have uncovered new research showing an increased risk of cancer with a group of blood pressure medications known as angiotensin-receptor blockers (ARBs).
This class of drugs is used by millions of patients not only for hypertension but also for heart failure, cardiovascular risk reduction and diabetic kidney disease.
University Hospitals Harrington-McLaughlin Heart & Vascular........Go to the Cancer-blog (Added on 6/13/2010 10:35:42 PM)
Polyphenols in red wine and greenIn what could lead to a major advance in the therapy of prostate cancer, researchers now know exactly why polyphenols in red wine and green tea inhibit cancer growth. This new discovery, published online in The FASEB Journal (http://www.fasebj.org), explains how antioxidants in red wine and green tea produce a combined effect to disrupt an important cell signaling pathway necessary for prostate cancer growth. This finding is important because........Go to the Prostate-cancer-blog (Added on 6/9/2010 11:18:48 PM)
An enzyme important for cancer's ability to spreadIn collaboration with the National Cancer Centre, Singapore, Van Andel Research Institute (VARI) scientists have identified an enzyme that could help diagnose and treat cholangiocarcinoma, a form of liver cancer that strikes up to 3,000 new patients each year in the United States.
Cholangiocarcinoma is the second most common type of cancer that affects the hepatobiliary system, which includes the liver, gall bladder, and bile ducts. The........Go to the Cancer-blog (Added on 6/9/2010 6:47:02 AM)
Surgery in men with low-risk prostate cancerJohns Hopkins experts have found that men enrolled in an active surveillance program for prostate cancer that eventually needed surgery to remove their prostates fared just as well as men who opted to remove the gland immediately, except if a follow-up biopsy during surveillance showed high-grade cancer.
Active surveillance, or "watchful waiting," is an option open to men whose tumors are considered small, low-grade and at low risk of being........Go to the Prostate-cancer-blog (Added on 6/9/2010 6:42:27 AM)
Protein may repair damage from multiple sclerosisA protein that helps build the brain in infants and children may aid efforts to restore damage from multiple sclerosis (MS) and other neurodegenerative diseases, scientists at Washington University School of Medicine in St. Louis have found.
In a mouse model of MS, scientists observed that the protein, CXCR4, is essential for repairing myelin, a protective sheath that covers nerve cell branches. MS and other disorders damage myelin, and this........Go to the Neurology news blog (Added on 6/8/2010 7:05:38 AM)
Cost of caring for stroke patientsHealth-care costs for patients in just the first six months after they have a stroke is more than $2.5 billion a year in Canada, as per a research studypresented today at the Canadian Stroke Congress.
The Canadian Stroke Network's Burden of Ischemic Stroke (BURST) study observed that the direct and indirect health-care costs for new stroke patients tally an average $50,000 in the six-month period following a new stroke. There are about........Go to the Neurology news blog (Added on 6/8/2010 6:36:26 AM)
Vandetanib shows clinical benefit for lung cancerWhen combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted treatment vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, as per research from The University of Texas MD Anderson Cancer Center.
The findings, reported in the Lancet Oncology, mark the first clinical benefit of a small molecule targeted agent and standard chemotherapy in combination........Go to the Lung-cancer-blog (Added on 6/7/2010 6:50:05 AM)
Regular bedtimes for childrenChildren in households with bedtime rules and children who get adequate sleep score higher on a range of developmental evaluations, as per a research abstract that will be presented Monday, June 7, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.
Results indicate that among sleep habits, having a regular bedtime was the most consistent predictor of positive developmental........Go to the Pediatric news blog (Added on 6/7/2010 6:41:50 AM)
Exercise to reduce depressionQuebec You don't always need to build up a big sweat to reap the healing benefits of physical activity. Research has observed that even a low-intense exercise program can reduce depression symptoms and boost physical treatment results in recovering stroke patients.
"The power of physical activity to raise the spirits of recovering stroke patients is stronger than anyone suspected," Heart and Stroke Foundation researcher Dr. Jocelyn Harris........Go to the Psychology news blog (Added on 6/7/2010 6:36:55 AM)
Smoke-free air laws effectiveScientists at the Harvard School of Public Health (HSPH) have observed that children and adolescents living in non-smoking homes in counties with laws promoting smoke-free public places have significantly lower levels of a common biomarker of secondhand smoke exposure than those living in counties with no smoke-free laws.
The children living in non-smoking homes in U.S. counties with smoke-free laws had 39% lower prevalence of cotinine in........Go to the Society medical news blog (Added on 6/7/2010 6:32:02 AM)
New treatment regimen for ovarian cancerNewly reported results from a major clinical trial show that adding bevacizumab (Avastin) to standard frontline chemotherapy for women with advanced ovary cancer and then continuing one of the majortenance dose of the drug afterwards significantly extends progression-free survival. Women receiving the new therapy regimen saw no worsening of their disease for 14.1 months, in comparison to 10.3 months for women receiving standard treatment.
........Go to the Ovarian cancer blog (Added on 6/6/2010 8:40:53 PM)
Fighting leukemia with two-pronged therapyA new treatment mounts a double-barreled attack on leukemia, targeting not just the cancer cells but also the environment in which those cells live and grow, University of Florida scientists report.
Like striking an enemy camp directly as well as cutting off its source of food and other resources, the agent, called Oxi4503, poisons leukemia cells and destroys the blood vessels that supply them with oxygen and nutrients.
Use of the therapy........Go to the Cancer-blog (Added on 6/4/2010 6:40:20 AM)