Why certain ovarian cancers develop resistanceA team of scientists led by Fred Hutchinson Cancer Research Center has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to therapy with usually used platinum-based chemotherapy drugs such as cisplatin and carboplatin. They describe their research online Feb. 10 in the journal Nature.
While these findings are based on the study of ovarian-cancer cells from women with inherited mutations in the BRCA2........Go to the Ovarian cancer blog (Added on 2/10/2008 9:47:52 PM)
Artificial sweeteners linked to weight gainWant to lose weight" It might help to pour that diet soda down the drain. Scientists have laboratory evidence that the widespread use of no-calorie sweeteners may actually make it harder for people to control their intake and body weight. The findings are reported in the recent issue of Behavioral Neuroscience, which is published by the American Psychological Association (APA).
Psychology experts at Purdue Universitys Ingestive Behavior........Go to the Weight watcher's blog (Added on 2/10/2008 9:43:38 PM)
PET Outperforms CT In Malignant Lung NodulesScientists involved in a large, multi-institutional study comparing the accuracy of positron emission tomography (PET) and computed tomography (CT) in the characterization of lung nodules observed that PET was far more reliable in detecting whether or not a nodule was cancerous.
"CT and PET have been widely used to characterize solitary pulmonary nodules (SPNs) as non-malignant or cancerous," said James W. Fletcher, professor of radiology at........Go to the Lung-cancer-blog (Added on 2/6/2008 9:22:16 PM)
Dairy Products For Healthy GumsConsumers have long known that including dairy in their diets can help maintain healthy bones and even help promote weight loss. However, a recent study reported in the recent issue of the Journal of Periodontology, the official publication of the American Academy of Periodontology (AAP), demonstrated that routine intake of dairy products may also help promote periodontal health. The study analyzed the periodontal health of 942 subjects and........Go to the Society medical news blog (Added on 2/6/2008 8:33:58 PM)
Novel Molecules Can Boost Vaccine PotencyTwo novel proteins studied by a University at Buffalo professor of microbiology and immunology appear to have the potential to enhance the production of antibodies against a multitude of infectious agents.
Terry D. Connell, Ph.D., professor of microbiology and immunology in the Witebsky Center for Microbial Pathogenesis in the UB School of Medicine and Biomedical Sciences, developed and patented the LT-IIa and LT-IIb enterotoxins and their........Go to the Infectious disease blog (Added on 2/6/2008 5:24:38 AM)
Key interaction in cholesterol regulationScientists at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called bad cholesterol, from the blood.
The practical benefit of this finding is that we can now search for new ways to lower cholesterol by designing targeted antibodies to disrupt this interaction, said Dr. Jay Horton, professor of internal........Go to the Heart-watch-blog (Added on 2/4/2008 10:23:42 PM)
Women prefer contraceptive ring over patchIn the first study to directly compare a contraceptive vaginal ring and skin patch, more women indicated overall satisfaction with the vaginal ring, scientists report in the current issue of Obstetrics and Gynecology, a publication of the American College of Obstetricians and Gynecologists. Using the same combination of hormones included in prescription birth control pills, these products became available in 2002 as an alternative to taking a........Go to the OBGYN news blog (Added on 2/4/2008 9:39:18 PM)
2009 Bush budget a disaster for HIV/AIDSThe Presidents proposed budget for fiscal year 2009, if enacted, would spell disaster for the nations health, and by extension, our national effort to respond to the HIV/AIDS epidemic in the United States.
The Administrations budget flat-funds critical federal support for research at the National Institutes of Health (NIH), public health programs at the Centers for Disease Control and Prevention (CDC), and vital health care safety net........Go to the Infectious disease blog (Added on 2/4/2008 8:41:27 PM)
BRCA1 mutation linked to breast cancer stem cellsA new study may explain why women with a mutation in the BRCA1 gene face up to an 85 percent lifetime risk of breast cancer.
Scientists from the University of Michigan Comprehensive Cancer Center observed that BRCA1 plays a role in regulating breast stem cells, the small number of cells that might develop into cancers.
The study, in mice and in human breast cancer cells, observed that BRCA1 is involved in the stem cells differentiating........Go to the Breast-cancer-blog (Added on 1/31/2008 10:56:09 PM)
Sugary soft drinks linked to increased risk of goutConsumption of sugar sweetened soft drinks and fructose is strongly linked to an increased risk of gout in men, finds a study published on bmj.com today.
Gout is a joint disease which causes extreme pain and swelling. It is most common in men aged 40 and older. It is caused by excess uric acid in the blood (hyperuricaemia) which leads to uric acid crystals collecting around the joints.
In the United States, levels of gout have doubled........Go to the Society medical news blog (Added on 1/31/2008 10:13:51 PM)
Is the obesity epidemic exaggerated?Last week, the UK health secretary declared that we are in a grip of an obesity epidemic, but does the evidence stack up? Scientists in this weeks BMJ debate the issue.
Claims about an obesity epidemic often exceed the scientific evidence and mistakenly suggest an unjustified degree of certainty, argue Patrick Basham and John Luik.
For example, the average population weight gain in the United States in the past 42 years is 10.9kg or........Go to the Weight watcher's blog (Added on 1/31/2008 9:53:01 PM)
African-Americans less likely to choose epiduralsMinority and low-income patients are less likely than those who are white or more well off to agree to post-surgery epidural pain relief, as per new research from physicians at the University of Pennsylvania School of Medicine. The study, published recently in the journal Anesthesia and Analgesia, examined how race, economic and educational status may influence health care choices when access to care isnt a factor. In the overall analysis,........Go to the OBGYN news blog (Added on 1/31/2008 8:56:42 PM)
Links between prostate cancer, cadmium, and zincCadmium exposure is a known risk factor for prostate cancer, and a new University of Rochester study suggests that zinc may offer protection against cadmium.
In an article reported in the February 2008 journal, The Prostate, epidemiologist Edwin van Wijngaarden, Ph.D., reports that PSA levels were 22 percent higher among American men who had zinc levels below the median (less than 12.67 mg/daily) and cadmium levels above the median. (PSA is........Go to the Prostate-cancer-blog (Added on 1/30/2008 9:20:44 PM)
CHD Patients Continue With Poor DietMore than 13 million Americans have survived a heart attack or have been diagnosed with coronary heart disease (CHD), the number one cause of death in the United States. In addition to medications, changes in lifestyle, such as a healthy diet and exercise, are known to reduce the risk for subsequent cardiac events. Despite this evidence, a high proportion of heart attack survivors do not follow their doctor's advice to adhere to a healthy diet,........Go to the Heart-watch-blog (Added on 1/30/2008 9:04:32 PM)
New Treatment Target for AsthmaAn enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma - pointing to a potential new target for therapy against the illness.
Reporting in the online edition of Proceedings of the National Academy of Sciences, a team at Weill Cornell Medical College explains that during an immune response, mast cells release the enzyme - called renin - which in turn produces........Go to the Allergy news blog (Added on 1/29/2008 9:26:36 PM)
Number of Russian women smokers has doubledIn 1992, seven per cent of women smoked, in comparison to almost 15 per cent by 2003. In the same period, the number of men who smoke has risen from 57 per cent to 63 per cent.
The scientists behind the study, reported in the journal Tobacco Control, blame the privatisation of the previously state owned tobacco industry and the behaviour of the transnational tobacco companies (TTCs) for what they describe as a "very worrying increase".
........Go to the Society medical news blog (Added on 1/28/2008 10:57:13 PM)
Over-the-counter eardrops may cause hearing lossA new study, led by scientists at The Montreal Childrens Hospital (MCH) of the MUHC, has revealed that certain over-the-counter earwax softeners can cause severe inflammation and damage to the eardrum and inner ear. The results of the study, recently published in The Laryngoscope, suggest that use of these medications should be discouraged.
Patients often complain that wax is blocking their ears and is causing discomfort and sometimes........Go to the ENT news blog (Added on 1/28/2008 10:50:46 PM)
Diuretics Excel in Drug Comparison TrialDiuretics were linked to reduced heart disease in a drug comparison trial involving 23,077 people with both hypertension and the metabolic syndrome, a cluster of risk factors for heart disease, report scientists from The University of Texas School of Public Health and Case Western Reserve University in the Jan. 28 issue of the Archives of Internal Medicine, one of the JAMA/Archives journals. The cardiac benefits connected with diuretics were........Go to the Heart-watch-blog (Added on 1/28/2008 10:20:40 PM)
Cutting caffeine may help control diabetesDaily consumption of caffeine in coffee, tea or soft drinks increases blood sugar levels for people with type 2 diabetes and may undermine efforts to control their disease, say researchers at Duke University Medical Center.
Scientists used new technology that measured participants glucose (sugar) levels on a constant basis throughout the day. Dr. James Lane, a psychology expert at Duke and the lead author of the study, says it represents the........Go to the Diabetic news blog (Added on 1/28/2008 5:16:29 AM)
New MIT tool probes brain circuitsScientists at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science that they have created a way to see, for the first time, the effect of blocking and unblocking a single neural circuit in a living animal.
This revolutionary method allowed Susumu Tonegawa, Picower Professor of Biology and Neuroscience, and his colleagues to see how bypassing a major memory-forming circuit in the brain affected........Go to the Neurology news blog (Added on 1/24/2008 11:17:50 PM)
Smart pillbox could be a lifesaverIn The World is a new column that explores the ways people from MIT are using technology--from the appropriately simple to the cutting edge--to help meet the needs of local people in places around the planet. If you know of a good example and would like the News Office to write about it, please e-mail email@example.com.
Tuberculosis has long been eradicated from the world's industrialized nations but continues to take a terrible toll in a few........Go to the Society medical news blog (Added on 2/10/2008 9:55:10 PM)
Effort To Sequence 1,000 Human GenomesWashington University School of Medicine in St. Louis will play a leading role in an international collaboration to sequence the genomes of 1,000 individuals. The ambitious 1000 Genomes Project will create the most detailed picture to date of human genetic variation and likely will identify a number of genetic factors underlying common diseases.
Drawing on the expertise of research teams in the United States, China and England, the project........Go to the Research news blog (Added on 2/7/2008 10:04:52 PM)
Adolescent Reaction to Iraq WarUniversity of Cincinnati scientists are reporting what they call a significant pattern among Iraqi adolescents and their reaction to the war in Iraq - the higher the perceived threat of the war, the higher the teens reported their self-esteem. The findings - from a 2004 survey of 1,000 Iraqi adolescents in 10 neighborhoods in Baghdad - are published in the current issue of the Journal of Adolescence.
Steve Carlton-Ford, a University of........Go to the Psychology news blog (Added on 2/6/2008 9:15:15 PM)
Two Different Peels Both Effective in AcneChemical peels using either alpha-hydroxy acid or beta-hydroxy acid are both highly effective in treating mild to moderately severe facial acne, scientists at the Saint Louis University School of Medicine have found - the first study to compare the two different types of acid peels as therapies for the skin disorder.
Peels using beta-hydroxy acid (or BHA) had slightly fewer side effects and results that lasted a bit longer than did peels........Go to the Skin news blog (Added on 2/6/2008 9:03:35 PM)
Inadequate diagnostic criteria for eating disordersProvidence, RI A new study by Rhode Island Hospital and Brown University suggests that the DSM-IV criteria for eating disorders have limited clinical utility. Scientists recommend a broadening of the criteria for bulimia, anorexia and binge eating disorder.
In the DSM-IV manual, bulimia and anorexia nervosa are the only officially recognized and formally defined eating disorders. A third, binge eating disorder, is listed in the Appendix as........Go to the Weight watcher's blog (Added on 2/6/2008 5:19:48 AM)
Button mushrooms contain much anti-oxidantsThe humble white button mushroom (Agaricus bisporus) has as much, and in some cases, more anti-oxidant properties than more expensive varieties.
Eventhough the button mushroom is the foremost cultivated edible mushroom in the world with thousands of tonnes being eaten every year, it is often thought of as a poor relation to its more exotic and expensive cousins and to have lesser value nutritionally.
But as per new research in SCIs........Go to the Weight watcher's blog (Added on 2/6/2008 5:17:56 AM)
Grapefruit compound may help combat hepatitis CA compound that naturally occurs in grapefruit and other citrus fruits may be able to block the secretion of hepatitis C virus (HCV) from infected cells, a process mandatory to maintain chronic infection. A team of scientists from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) report that HCV is bound to very low-density lipoprotein (vLDL, a so-called bad cholesterol) when it is secreted from liver cells and........Go to the Infectious disease blog (Added on 2/4/2008 9:50:56 PM)
Microneedles enhance drug administrationIn what is thought to bethe first peer-evaluated study of its kind involving human subjects, scientists at the University of Kentucky College of Pharmacy and the Georgia Institute of Technology have demonstrated that patches coated on one side with microscopic needles can facilitate transdermal delivery of clinically-relevant doses of a drug that normally cannot pass through the skin.
Published in the journal Proceedings of the National........Go to the Research news blog (Added on 2/4/2008 9:21:53 PM)
Survival rates of premature infantsSurvival rates for the most premature babies at a top London hospital have more than doubled over a 20 year period, as per research reported in the latest edition of the journal Acta Paediatrica.
The study, led by scientists at University College London (UCL) and University College London Hospitals NHS Foundation Trust (UCLH), suggests significant improvements in survival rates can be achieved when maternity and neonatal units have........Go to the Pediatric news blog (Added on 1/31/2008 10:59:11 PM)
Severe hypertension: 'Silent killer' still on the looseHonolulu, HI Hypertension may be one of the top killers in the country, but youd never know it by the way were behaving, say researchers attending the annual congress of the Society for Critical Care Medicine (SCCM).
Research shows that some 73 million people in the U.S. have high blood pressure, yet a number of of them dont even know it. And among those that do, a large number are not taking the medications they need to control it," says........Go to the Heart-watch-blog (Added on 1/31/2008 10:53:35 PM)
Parenting program does not prevent toddler behavior problemsA study of the first universal parenting programme, designed to prevent early child behaviour problems, shows that it has little impact on toddler behaviour.
The study, conducted at the Centre for Community Child Health (CCCH) in Melbourne, Australia, is published on bmj.com today.
Behaviour problems affect up to 20 per cent of children and have major personal, societal and economic ramifications. Left untreated, up to half of behaviour........Go to the Psychology news blog (Added on 1/31/2008 9:55:02 PM)
FDA about updating requirements for drug approvalResearchers and the Food and Drug Administration (FDA) are discussing how new technologies in ophthalmology, which make it possible to collect better data about experimental therapys, might affect FDA clinical trials requirements.
Scientists from the National Institutes of Healths National Eye Institute (NEI) and major US universities and research centers met in a roundtable discussion with FDA representatives before an audience of their........Go to the Society medical news blog (Added on 1/31/2008 8:38:58 PM)
Blue-eyed humans have a single, common ancestorNew research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today.
What is the genetic mutation.
"Originally, we all had brown eyes", said Professor Eiberg from the Department of Cellular and Molecular Medicine. "But a genetic........Go to the Society medical news blog (Added on 1/30/2008 9:14:04 PM)
The eyes Tell It AllUsing the radiocarbon dating method and special proteins in the lens of the eye, scientists at the University of Copenhagen and Aarhus can now establish, with relatively high precision, when a person was born. This provides a useful tool for forensic researchers who can use it to establish the date of birth of an unidentified body and could also have further consequences for health science research. The findings appear in the online,........Go to the Ophthalmology news blog (Added on 1/29/2008 10:08:56 PM)
Digital mammography superior to film mammographyFor some women, digital mammography may be a better screening option than film mammography, as per newly published results from a national study led by a University of North Carolina at Chapel Hill researcher.
The results, from the Digital Mammographic Imaging Screening Trial (DMIST), appear in the recent issue of Radiology. UNCs Dr. Etta D. Pisano is principal investigator and lead author of the study, which observed that digital........Go to the Breast-cancer-blog (Added on 1/29/2008 9:24:29 PM)
Creative and noncreative problem solversWhy do some people solve problems more creatively than others? Are people who think creatively somehow different from those who tend to think in a more methodical fashion? .
These questions are part of a long-standing debate, with some scientists arguing that what we call creative thought and noncreative thought are not basically different. If this is the case, then people who are thought of as creative do not really think in a........Go to the Society medical news blog (Added on 1/29/2008 9:22:08 PM)
The smaller the tumor, the better your chancesThe odds of surviving cancer of the pancreas increase dramatically for patients whose tumors are smallest, as per a new study by scientists at Saint Louis University and the M.D. Anderson Cancer Center in Houston the first study to specifically evaluate the link between tumor size and survival rates for one of the most common and deadly cancers.
The findings in the current edition of Pancreas (www.pancreasjournal.com) vividly underscore........Go to the Pancreatic cancer blog (Added on 1/28/2008 10:31:20 PM)
Device Zeroes in on Small Breast TumorsA new medical imager for detecting and guiding the biopsy of suspicious breast cancer lesions is capable of spotting tumors that are half the size of the smallest ones detected by standard imaging systems, as per a new study.
The results of initial testing of the PEM/PET system, designed and constructed by researchers at the Department of Energy's Thomas Jefferson National Accelerator Facility, West Virginia University School of Medicine and........Go to the Breast-cancer-blog (Added on 1/28/2008 10:26:35 PM)
Stroke victims may benefit from stem cell transplantsTampa, Fla. (Jan. 28, 2008) As per two studies reported in the current issue of CELL TRANSPLANTATION (Vol.16 No.10), stroke victims may benefit from human mesenchymal stem cell (hMSC) or bone marrow stromal cell (BMSCs) transplantation. In both studies, the migration of chemically tagged transplanted stem cells were tracked to determine the degree to which the transplanted cells reached damaged areas of the brain and became therapeutically........Go to the Neurology news blog (Added on 1/28/2008 5:14:26 AM)
Drug that may prevent radiation injuryThe Department of Defense has commissioned a nine-month study from Rice University chemists and researchers in the Texas Medical Center to determine whether a new drug based on carbon nanotubes can help prevent people from dying of acute radiation injury following radiation exposure. The new study was commissioned after preliminary tests found the drug was greater than 5,000 times more effective at reducing the effects of acute radiation injury........Go to the Health news blog (Added on 1/28/2008 5:13:15 AM)