Increased Survival In Metastatic Colorectal CancerA phase III trial of 1,298 colorectal cancer patients has observed that a combination of the drugs cetuximab (Erbitux) and irinotecan showed a significant improvement in progression-free survival over just irinotecan alone, as per an international team of researchers.
The Erbitux Plus Irinotecan in Colorectal Cancer (EPIC) study looked at survival in metastatic colorectal cancer patients who had already shown resistance to conventional........Go to the Colon-cancer-blog (Added on 4/17/2007 5:07:18 AM)
Gene Crucial For Nerve Cell InsulationScientists funded by the National Institutes of Health have discovered how a defect in a single master gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals.
The discovery has implications for understanding disorders of myelin production. These disorders can affect the peripheral nervous systemthe nerves outside........Go to the Neurology news blog (Added on 4/17/2007 5:05:08 AM)
A Pancreas Cancer Risk ModelPeople with a family history of pancreatic cancer now have a way to accurately predict their chance of carrying a gene for hereditary pancreatic cancer and their lifetime risk of developing the disease. Developed by Johns Hopkins Kimmel Cancer Center researchers, the novel computer software tool is designed to help genetic counselors and physicians decide who would most benefit from early screening.
An estimated 10 percent of aggressive and........Go to the Pancreatic cancer blog (Added on 4/16/2007 10:05:28 PM)
alcohol and sleep-related breathing disorderIncreased usual alcohol consumption among men is linked to an increased risk of a mild or worse sleep-related breathing disorder (SRBD), as per a research studyreported in the April 15th issue of the Journal of Clinical Sleep Medicine (JCSM).
The study, authored by Paul E. Peppard, PhD, and his colleagues at the University of Wisconsin-Madison, focused on 775 men and 645 women, who were reviewed for alcohol consumption and a sleep-related........Go to the Society medical news blog (Added on 4/15/2007 9:14:09 PM)
Genetics, society and raceMinority individuals are much more likely to develop and die from cancer than the general U.S. population. Prior research points to lack of health insurance, poverty, language and cultural barriers, and inadequate access to early detection services and good medical care as causes. Research reported today at the 2007 Annual Meeting of the American Association for Cancer Research (AACR) suggests that genetics, in addition to socioeconomic status,........Go to the Society medical news blog (Added on 4/15/2007 9:05:34 PM)
New non-invasive diagnostic technologiesMolecular messages and signals circulating in blood or contained in cells lining the airway can identify early stage cancer, as per research reported today at the 2007 Annual Meeting of the American Association for Cancer Research. Researchers looking to apply basic science knowledge to medical practice are in the process of developing tests that diagnose, predict or monitor cancer risks, without invasive tissue sampling. Such tests could........Go to the Cancer-blog (Added on 4/15/2007 8:56:47 PM)
DNA Test Can Be Early Predictor Of Liver CancerScientists at Columbia Universitys Mailman School of Public Health have discovered a means for early detection of liver cancer. Using DNA isolated from serum samples as a baseline biomarker, the researchers examined changes in certain tumor suppressor genes that have been linked to the development of liver carcinomas. This is the first study to prospectively examine potential biomarkers for early detection of liver cancer in high-risk........Go to the Cancer-blog (Added on 4/15/2007 8:36:50 PM)
Genetic Risk Factors For Crohn's DiseaseAn international research team including researchers from Massachusetts General Hospital (MGH) and the Broad Institute of Harvard University and Massachusetts Institute of Technology has identified several novel genetic variations linked to the risk of Crohn's disease. One of the identified genes establishes a role for autophagy, a previously unsuspected biological pathway, in Crohn's disease pathology; and the report documents functional........Go to the GI news blog (Added on 4/15/2007 8:29:57 PM)
Hope For Early Diagnosis Of Alzheimer'sResearch by faculty and staff at Rowan University, Glassboro, N.J.; the University of Pennsylvania School of Medicine; and Drexel University may lead to better diagnosis of early-stage Alzheimers disease.
In a $1.1-million National Institutes of Healths National Institute on Aging study that team members conducted during the last three years, they determined early Alzheimers could be diagnosed with a high rate of accuracy evaluating........Go to the Neurology news blog (Added on 4/13/2007 4:57:08 PM)
New Reflux Guidelines ReleasedNew, updated guidelines for esophageal reflux testing appear in The American Journal of Gastroenterology. Developed and approved by the American College of Gastroenterology, these guidelines summarize advances in gastroesophageal reflux disease (GERD) diagnostic testing and how they have modified the clinical management of esophageal disorders.
"Gastroenterologists are confronted with an increasing number of patients presenting symptoms of........Go to the GI news blog (Added on 4/13/2007 4:43:47 PM)
Stress may help cancer cells resist treatmentResearchers from Wake Forest University School of Medicine are the first to report that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death.
"These data imply that emotional stress may contribute to the development of cancer and may also reduce the effectiveness of cancer therapys," said George Kulik, D.V.M., Ph.D., an assistant professor of cancer biology and senior........Go to the Cancer-blog (Added on 4/11/2007 11:08:28 PM)
Liver regeneration may be simplerThe way the liver renews itself may be simpler than what researchers had been assuming. A new study, appearing in the April 13 issue of The Journal of Biological Chemistry, provides new information on the inner workings of cells from regenerating livers that could significantly affect the way physicians make livers regrow in patients with liver diseases such as cirrhosis, hepatitis, or cancer.
"The human liver is one of the few organs in the........Go to the GI news blog (Added on 4/11/2007 10:21:43 PM)
Nanoparticles improve delivery of medicinesTiny, biodegradable particles filled with medicine may also contain answers to some of the biggest human health problems, including cancer and tuberculosis. The secret is the size of the package.
Using an innovative technique they invented, a Princeton University-led research team has created particles that can deliver medicine deep into the lungs or infiltrate cancer cells while leaving normal ones alone. Only 100 to 300 nanometers wide --........Go to the Research news blog (Added on 4/10/2007 8:42:42 PM)
Protein Required For Two Neighboring Cells To FuseWorking with fruit flies, researchers at Johns Hopkins have discovered a protein mandatory for two neighboring cells to fuse and become one "super cell."
Most cells enjoy their singular existence, but the strength and flexibility of muscles relies on hundreds or even thousands of super cells that make large-scale motion smooth and coordinated, such as flexion of a bicep.
The newly discovered protein, dubbed Solitary, coordinates the........Go to the Research news blog (Added on 4/10/2007 6:06:18 PM)
Chance of hysterectomy predictedA woman's chance of undergoing a hysterectomy can now be accurately predicted, as per new UCSF study findings.
Results from a four-year study of 762 women with various symptoms of uterine distress, such as chronic pelvic pain, abnormal bleeding or fibroids, are published in the April 2007 issue of the "Journal of the American College of Surgeons." Study findings also are available online at www.journalacs.org
The findings confirm a........Go to the OBGYN news blog (Added on 4/9/2007 11:03:43 PM)
Rabies-based Vaccine Against HivRabies, a relentless, ancient scourge, may hold a key to defeating another implacable foe: HIV. Researchers at Jefferson Medical College in Philadelphia have used a drastically weakened rabies virus to ferry HIV-related proteins into animals, in essence, vaccinating them against an AIDS-like disease. The early evidence shows that the vaccine which doesnt protect against infection prevents development of disease.
Reporting April 1, 2007 in........Go to the Infectious disease blog (Added on 4/3/2007 10:46:36 PM)
Allergic Diseases and Autoimmune DiseasesA new study by scientists at Children's and the University of Washington (UW) identifies a correlation between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases. The study was reported in the April 1 edition of Nature Immunology.
Approximately 75 percent of autoimmune diseases occur in women, most frequently during the childbearing years. These diseases also comprise a significant portion of chronic........Go to the Pediatric news blog (Added on 4/3/2007 10:43:23 PM)
Men and Women See Things DifferentlyIn the hands of the wrong person, power can be dangerous. That's particularly the case in the workplace, where the abuse of power can lead to sexual harassment.
Issues of power, workplace culture and the interpretation of verbal and non-verbal communication linked to sexual harassment were the focus of a study by Debbie Dougherty, assistant professor of communication in the College of Arts and Science at the University of Missouri-Columbia.........Go to the Psychology news blog (Added on 4/3/2007 10:15:33 PM)
Primary Medical Care For Children With AutismChildren with autism do not receive the same quality of primary care as children with other special health care needs, as per research from the University of Minnesota Medical School.
A study reported in the Archives of Pediatrics and Adolescent Medicine observed that parents of children with autism were less likely to report that their children received the type of primary care advocated by the American Academy of Pediatrics (AAP) when in........Go to the Pediatric news blog (Added on 4/2/2007 10:14:06 PM)
The formation of social memoriesIs there a specific memory for events involving people? Scientists in the Vulnerability, Adaptation and Psychopathology Laboratory (CNRS/University Paris VI France ) and a Canadian team at Douglas Hospital, McGill University (Montreal), have identified the internal part of the prefrontal cortex as being the key structure for memorising social information. Published in Journal of Cognitive Neuroscience, February 2007.
Social events such as a........Go to the Neurology news blog (Added on 4/1/2007 9:32:20 PM)
Treating Alzheimer's Diseasemolecule designed by a Purdue University researcher could lead to the first drug therapy for Alzheimer's disease.
"There are a number of people suffering, and no effective therapy is available to them," said Arun Ghosh, the Purdue professor who designed the molecule. "There is an urgent need for a drug to treat this devastating disease, and the scientific community has been working on this problem for a number of years".
The National........Go to the Neurology news blog (Added on 4/17/2007 10:56:03 PM)
Change in neuroticism tied to mortality ratesWhile mellowing with age has often been thought to have positive effects, a Purdue University researcher has shown that doing so could also help you live longer.
Dan Mroczek (pronounced Mro-ZAK), an associate professor of child development and family studies at Purdue University, compared neurotic and non-neurotic men over time and tied change in the trait with mortality.
"We observed that neurotic men whose levels dropped over time had a........Go to the Neurology news blog (Added on 4/17/2007 4:49:15 AM)
Strong Marriage And Temperamental BabyCouples with infants who are especially fussy or difficult typically do just fine as parents - as long as they have a strong marital relationship.
A new study observed that a couple's relationship with each other was key in determining how they reacted as parents when faced with a temperamental baby.
"When couples with a supportive marital relationship have a difficult baby, they tend to rise to the challenge," said Sarah........Go to the Pediatric news blog (Added on 4/16/2007 9:16:23 PM)
Breathing for better lung healthWhile working to find novel ways to treat the life-threatening disease of cystic fibrosis, scientists at the University of North Carolina have discovered that the rhythmic motion of the lungs during normal breathing is a critical regulator of the clearance of bacteria and other noxious materials. Their research, funded by the Cystic Fibrosis Foundation and the National Institute of Health, is reported in the latest issue of The Journal of........Go to the Lung news blog (Added on 4/15/2007 9:23:18 PM)
Eating Well Is The Best RevengeWe all know that eating fruits, vegetables and soy products provides essential nutrition for a healthy lifestyle, while obesity leads to the opposite. Yet proving the effect of nutrition, or obesity, on cancer is an experimental challenge and a focus for scientists. As per emerging evidence being presented at the 2007 Annual Meeting of the American Association for Cancer Research, eating well might still be one of the more pleasurable ways to........Go to the Cancer-blog (Added on 4/15/2007 9:02:15 PM)
Targeted Therapy For A Specific Form Of LeukemiaLeukemia, or cancer of the bone marrow, strikes some 700 Belgians each year. Researchers are still searching for the cause of a number of forms of leukemia, including T-cell acute lymphoblastic leukemia, or T-ALL. Now, VIB scientists connected to the Katholieke Universiteit Leuven have identified a new player in the development of some 10% of the T-ALL cases: MYB. The researchers have discovered that patients in this group have a duplication of........Go to the Cancer-blog (Added on 4/15/2007 8:50:58 PM)
Factors Attributed To Later Stage Cancer DiagnosisScientists from the Keck School of Medicine of the University of Southern California (USC) observed that patients who received a later stage cancer diagnosis were likely to be living in an unsafe neighborhood, using public transportation and traveling at least 45 minutes to get to a doctor's office. The study will be presented at this week's American Association of Cancer Research (AACR) in Los Angeles on April 15.
A survey of more than 350........Go to the Cancer-blog (Added on 4/15/2007 8:33:31 PM)
How Microbes start immune responseImmune cells that are the bodys front-line defense dont necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan researchers describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.
The study, published online ahead of print in the recent issue of the........Go to the Infectious disease blog (Added on 4/13/2007 5:17:27 PM)
Childhood obesity among Quebec CreeChildhood obesity is increasing among the general population in Canada, but the statistics are even more alarming among First Nations, Inuit and Mtis children. As per a research findings published recently in the American Journal of Public Health, University of Alberta scientists observed that up to 65 per cent of Cree preschoolers in northern Quebec communities were overweight or obese.
Dr. Noreen Willows, a community nutritionist at the........Go to the Weight watcher's blog (Added on 4/13/2007 4:54:46 PM)
Not Just a Menopausal Symptomnew study in Psychophysiology confirms a surprising fact - men who have undergone chemical castration for conditions such as prostate cancer experience hot flashes similar to those experienced by menopausal women. Using a technique called sternal skin conductance, doctors were able to positively identify hot flashes in males, a positive step toward providing treatment for those patients in need.
"Most people are unaware that men can have hot........Go to the OBGYN news blog (Added on 4/13/2007 4:48:14 PM)
Genes set scene for metastasisBiologists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights targets for........Go to the Cancer-blog (Added on 4/11/2007 11:06:38 PM)
Key Player In Embryonic Muscle DevelopmentMuscle fibers are large cells that contain a number of nuclei. They begin, like all animal cells, as naive embryonic cells. These cells differentiate, producing intermediate cells called myoblasts that are now destined to become muscle. New myoblasts then seek out other myoblasts, and when they find each other, they stick together like best friends. In the final stage of muscle fiber development, the cell membranes of attached myoblasts open up........Go to the Research news blog (Added on 4/11/2007 10:27:41 PM)
Misusing vitamin to foil drug testTaking excessive doses of a common vitamin in an attempt to defeat drug screening tests may send the user to the hospitalor worse.
Scientists from The Children's Hospital of Philadelphia and The University of Pennsylvania reported on two adults and two adolescents who suffered toxic side effects from taking large amounts of niacin, also known as vitamin B3, in mistaken attempts to foil urine drug tests.
Both adult patients suffered skin........Go to the Society medical news blog (Added on 4/10/2007 6:34:35 PM)
Heavy Cost of Type 2 Diabetes ComplicationsA first-of-its-kind report looking at the prevalence and cost of type 2 diabetes complications shows that an estimated three out of five people (57.9 percent) with type 2 diabetes have at least one of the other serious health problems commonly associated with the disease, and that these health problems are taking a heavy financial toll on the United States. In 2006, the nation spent an estimated $22.9 billion on direct medical costs related to........Go to the Diabetic news blog (Added on 4/10/2007 6:33:17 PM)
Eye diseases for great paintersAfter writing two books on the topic of artists and eye disease, the Stanford University School of Medicine ophthalmologist decided to go one step further and create images that would show how artists with eye disease actually saw their world and their canvases. Combining computer simulation with his own medical knowledge, Marmor has recreated images of some of the masterpieces of the French impressionistic painters Claude Monet and Edgar Degas........Go to the Ophthalmology news blog (Added on 4/10/2007 6:00:25 PM)
How Lead Exposure Produces Learning DeficitsA study of young adult rats by scientists from the Johns Hopkins Bloomberg School of Public Health provides evidence that explains exactly how exposure to lead during brain development produces learning deficits. The study shows that exposure to levels of lead that are similar to those measured in lead-intoxicated children reduces the birth and survival of new neurons (neurogenesis) in the brain. Lead also alters the normal development of newly........Go to the Pediatric news blog (Added on 4/3/2007 10:49:03 PM)
Secondhand smoke proves to be seriousA study published in this months issue of the Journal of Periodontology observed that subjects with periodontitis who were exposed to secondhand smoke were more likely to develop bone loss, the number one cause of tooth loss.
Scientists studied rats that were induced with periodontal disease. One group was not exposed to cigarette smoke while the other two groups were exposed to either 30 days of smoke inhalation produced by non-light........Go to the Society medical news blog (Added on 4/3/2007 10:44:42 PM)
Parkinson drugs for stroke-related disabilityResearchers have untangled two similar disabilities that often afflict stroke patients, in the process revealing that one may be treatable with drugs for Parkinson's disease.
Scientists at Washington University School of Medicine in St. Louis showed that stroke damage in a brain region known as the putamen is strongly associated with motor neglect, a condition that makes patients slow to move toward the left side.
Like stroke patients........Go to the Neurology news blog (Added on 4/3/2007 10:40:44 PM)
Rapid response to 1918 flu pandemicOne of the persistent riddles of the deadly 1918 Spanish influenza pandemic is why it struck different cities with varying severity. Why were some municipalities such as St. Louis spared the fate of the hard-hit cities like Philadelphia when both implemented similar public health measures? What made the difference, as per two independent studies funded by the National Institutes of Health (NIH), was not only how but also how rapidly different........Go to the Infectious disease blog (Added on 4/2/2007 11:02:37 PM)
How a traumatic memory can be wiped outFrench CNRS researchers in collaboration have shown that a memory of a traumatic event can be wiped out, eventhough other, associated recollections remain intact. This is what a scientist in the Laboratory for the Neurobiology of Learning, Memory and Communication (CNRS/Orsay University), working with an American team, has recently demonstrated in the rat. This result could be used to cure patients suffering from post-traumatic stress.
........Go to the Neurology news blog (Added on 4/1/2007 9:35:47 PM)