Virulence Of 1918 Influenza VirusIt always puzzled the scientists, why the pandemic flu in 1918 was so rampant and the virus was so virulent.
The first comprehensive analysis of an animal's immune response to the 1918 influenza virus provides new insights into the killer flu, report federally supported researchers in an article appearing online today in the journal Nature. Key among these insights, they observed that the 1918 virus triggers a hyperactive immune response........Go to the Infectious disease blog (Added on 9/28/2006 8:31:12 PM)
Finger Length Ratio May Predict Women's Sporting ProwessThe difference between the lengths of a woman's index and ring fingers may indicate her sporting prowess, suggests research published ahead of print in the British Journal of Sports Medicine.
The finding supports other research indicating a possible link between this ratio and fertility, vulnerability to serious disease, intellectual ability, certain personality traits, and musical talent.
Most of the sporting research in this area has so........Go to the Society medical news blog (Added on 9/27/2006 9:24:55 PM)
Genetic Variations In Parkinson's DiseaseScientists at the National Institutes of Health (NIH) have completed one of the first large-scale studies of the role of common genetic variation in Parkinson's disease (PD). While the results fill in some missing pieces of the genetic puzzle, they are primarily of benefit as a starting point for more detailed studies. The information generated by the study is now publicly available in a database that will serve as a valuable research tool........Go to the Neurology news blog (Added on 9/27/2006 9:01:11 PM)
Brain Damage In Early Alzheimer's DiseaseScientists have developed a new computer-aided analysis technique to identify early cellular damage in Alzheimer's disease (AD). The study is featured in the recent issue of Radiology.
"With increasing longevity among the population, the occurence rate of AD is expected to rise rapidly, creating a great burden not only for patients and their families, but also for society," said Min-Ying Su, Ph.D., author and associate professor in the........Go to the Neurology news blog (Added on 9/27/2006 8:53:37 PM)
Spinal Cord Stimulators For Migraine HeadachesAnyone who has gone through the experience of migraine headache knows the misery of this miserable disease. Now there is some active research going on in this field that might interest those who are suffering from those miserable headaches.
A new therapy for migraine headaches is in the horizon: occipital nerve stimulation, a surgical procedure in which an implanted neurostimulator delivers electrical impulses to nerves under the skin at the........Go to the Neurology news blog (Added on 9/27/2006 7:20:48 PM)
Improving Patient's Meal ExperienceAnyone who had spent a day in the hospital knows about the quality of the hospital food. Now there is an innovative idea from the Rush University Medical Center.
Sometimes innovation in health care takes the form of advanced imaging technology or breakthroughs in drug therapys. Sometimes it takes the form of hamburgers cut into squares and soup served in a cup.
It may seem simple, but these innovations are making a big difference for........Go to the Health news blog (Added on 9/27/2006 6:37:53 PM)
Copper Helps Brain FunctionThe flow of copper in the brain has a previously unrecognized role in cell death, learning and memory, as per research at Washington University School of Medicine in St. Louis. The researchers' findings suggest that copper and its transporter, a protein called Atp7a, are vital to human thinking. They speculate that variations in the genes coding for Atp7a, as well as other proteins of copper homeostasis, could partially account for differences........Go to the Neurology news blog (Added on 9/26/2006 8:51:51 PM)
Most Complex Protein Knot Ever SeenAn MIT team has discovered the most complicated knot ever seen in a protein, and they believe it may be associated with the protein's function as a rescue agent for proteins marked for destruction.
"In proteins, the three-dimensional structure is very important to the function, and this is just one example," said Peter Virnau, a postdoctoral fellow in physics and an author of a paper on the work that appears in the Sept. 15 issue of the........Go to the Research news blog (Added on 9/25/2006 10:14:06 PM)
Gene Therapy For Prostate CancerScientists at Baylor College of Medicine (BCM) are hoping a new gene treatment that takes a gene called RTVP-1 directly into the prostate tumor will prove effective in preventing recurrence of the disease.
The first phase of the study is designed to test the safety of the therapy and determine the proper dosage of gene, said Dr. Dov Kadmon, professor of urology at BCM. It will be carried out in the department of urology at BCM as well as at........Go to the Prostate cancer news blog (Added on 9/25/2006 9:59:45 PM)
Latex-Free BalloonsVia Allergy blog
Yesterday, my son celebrated his birthday in the kindergarten. We brought a cake, which I made sure was nut-free, becasue aside from my son, there was one other child with nut allergies. We also brought some ballons, which was a hit among the kiddies, but in hindsight, could have caused a problem.
What if there was a child with latex allergies? or among the teachers? I didn't even bother to ask, bad me! Good thing that it........Go to the Allergy news blog (Added on 9/25/2006 7:18:10 PM)
Combination of Xeloda And Taxol Metastatic Breast CancerCombination of Xeloda and Taxol is an effective therapy for women with metastatic breast cancer. New research from US Oncology Network and the University of North Carolina has recently reported that the combination of Xeloda (capecitabine) and Taxol is an effective and tolerable regimen for initial therapy of women with metastatic breast cancer. Women who were HER-2 negative were not included in the study. This is a phase II study and it is........Go to the Breast-cancer-blog (Added on 9/25/2006 4:43:08 PM)
Breast Density Contributes to Breast Cancer RiskRecently there has been some discussion regarding inclusion of breast density in breast cancer prediction models. In a recent issue of the Journal of the National Cancer Institute this issue is highlighted. The discussion revolves around the question: should breast density be added to the Gail model in predicting breast cancer occurrence?
The Gail model is a breast cancer prediction tool that is widely used. Gail model estimates a woman's........Go to the Breast-cancer-blog (Added on 9/25/2006 4:33:09 PM)
Alcoholics Anonymous Reduces Homicides
Studies consistently show a strong link between alcohol use and violence, such as homicide. New research that looks at the relationship among drinking, Alcoholics Anonymous (AA) membership, and homicide mortality has observed that AA can have a beneficial effect on alcohol-related homicide mortality rates, especially among males who consume beer and spirits.
Results are reported in the recent issue of Alcoholism: Clinical & Experimental........Go to the Psychology news blog (Added on 9/24/2006 10:13:26 PM)
Decision-making Process In Alcoholics
People make decisions all the time: they form preferences, take action, and evaluate outcomes, whether rewarding or aversive. Impaired decision making is regarded as one of the neurobehavioral hallmarks of addiction. New research has observed that alcoholics with certain coexisting personality disorders (PDs) have decision-making abilities that are especially impaired.
Results are reported in the recent issue of Alcoholism: Clinical &........Go to the Psychology news blog (Added on 9/24/2006 10:07:29 PM)
Taller Women Are More Likely To Have TwinsTaller women are more likely to have twins according to experts. They suggest insulin-like growth factorr is responsible for this increased incedence. By comparing the heights of women who had given birth to twins or triplets with the average height of women in the United States, Gary Steinman, MD, PhD, an attending doctor at Long Island Jewish (LIJ) Medical Center, observed that the multiple-birth mothers averaged more than an inch taller. The........Go to the OBGYN news blog (Added on 9/23/2006 11:31:23 AM)
Eculizumab For The Treatment Of PNH A study led by Dr Peter Hillmen of the Leeds Teaching Hospitals NHS Trust, relating to an uncommon and severe haemolytic anaemia known as paroxysmal nocturnal haemoglobinuria (PNH), was reported in the current issue of The New England Journal (NEJM). In the Phase III efficacy study, TRIUMPH, 87 patients were treated at 34 sites in the U.S., Canada, Europe, and Australia. The data showed clinically significant improvements in anaemia and the........Go to the Health news blog (Added on 9/21/2006 4:44:38 AM)
Prenatal vitamins may reduce risk of brain tumors in childrenWomen who take multivitamins early in pregnancy may reduce the risk that their child will develop some types of brain tumors.
Public health agencies already urge pregnant women to take multivitamins that contain folic acid early in pregnancy to reduce their fetus's risk of developing a neural tube defect such as spina bifida. "This current study suggests another possible protective effect for the vitamins," said study leader Greta R. Bunin,........Go to the OBGYN news blog (Added on 9/20/2006 10:10:31 PM)
White Blood Cells And Transplanted KidneysIn an example of biological irony, the same white blood cell chemistry known to damage kidneys used for transplants may also help prevent such damage, as per a federally funded study in genetically engineered mice at Johns Hopkins.
Scientists have long known that when blood flow is cut off and then returned to transplanted kidneys or other organs, immune system cells called T lymphocytes produce toxic natural chemicals that contribute to........Go to the Kidney watch blog (Added on 9/20/2006 9:40:29 PM)
Why Food Tastes Bad To Chemotherapy RecipientsIt's a common experience among patients who are receiving chemotherapy to have no tast for food. About two million cancer patients currently receiving certain drug therapies and chemotherapy find foods and beverages to have a foul metallic flavor, as per a medical study. In general, more than 40 percent of hospitalized patients suffer from malnutrition due to taste and smell dysfunction.
"Unfortunately, these problems that impact nutrition........Go to the Cancer-blog (Added on 9/20/2006 5:09:29 AM)
Too little fat! May not be the best thingToo much body fat may be a bad thing, but there is increasing evidence that too little fat also may have some surprisingly negative consequences.
Scientists at UC Irvine have observed that fat droplets - tiny balls of fat that exist in most cells - appear to have an intriguing role to play when it comes to regulating excess proteins in the body. In a study with fruit flies, developmental biologist Steven Gross and his colleagues observed........Go to the Research news blog (Added on 9/19/2006 10:06:28 PM)
Largest US Study On HIV Treatment In WomenTibotec Therapeutics Clinical Affairs, a division of Ortho Biotech Clinical Affairs, LLC, announced recently the initiation of the largest clinical study conducted to date in therapy-experienced adult women with HIV to evaluate gender differences in response to an HIV medication.
GRACE (Gender, Race And Clinical Experience), a multi-center, open-label Phase IIIb trial, will compare gender differences in the efficacy, safety and tolerability........Go to the Infectious disease blog (Added on 9/28/2006 8:33:47 PM)
Abortion Notification And ConsentLaws that require minors to notify or get the consent of one or both parents before having an abortion reduce risky sexual behavior among teens, as per a Florida State University law professor in Tallahassee, Fla.
Jonathan Klick, the Jeffrey A. Stoops Professor of Law, and Thomas Stratmann, professor of economics at George Mason University, came to that conclusion after they looked at the rates of gonorrhea among teenage girls as a measure........Go to the OBGYN news blog (Added on 9/27/2006 9:22:08 PM)
Binge-drinking teenagersTeenagers who drink alcohol are at higher risk of becoming victims of violence, a Cardiff University study has observed.
A team from the School of Dentistry's Violence Research Group studied drinking habits in children aged 11-16 in England. They found not only a link between drink and aggression but also that children who drank were more likely to be hit, even if they weren't violent themselves.
The scientists are now calling for........Go to the Psychology news blog (Added on 9/27/2006 9:11:59 PM)
The Mystery of Flesh-Eating BacteriaA Howard Hughes Medical Institute (HHMI) international research scholar in Israel has discovered one reason why so-called "flesh-eating" bacteria are so hard to stop.
Emanuel Hanski, a microbiologist at Hebrew University in Jerusalem, and his colleagues have observed that the success of group A Streptococcus is due in part to a protein that blocks the immune system's distress calls. The findings, reported in the October 4, 2006, issue of the........Go to the Infectious disease blog (Added on 9/27/2006 8:35:07 PM)
Islet Transplantation Has Potential BenefitsThe results of the world's first multicenter clinical trial of islet transplantation have confirmed the technique's potential benefits in patients with difficult-to-control type 1 (or "juvenile") diabetes. Reported in the September 28, 2006 issue of the New England Journal (NEJM), the international team of researchers report that the Edmonton Protocol for islet transplantation can safely and successfully promote long-term stabilization of........Go to the Diabetes-watch-blog (Added on 9/27/2006 8:20:03 PM)
IMRT Cures Prostate CancerResults from the largest study of men with prostate cancer treated with high-dose, intensity modulated radiation treatment (IMRT) show that the majority of patients remain alive with no evidence of disease after an average follow-up period of eight years. The 561 patients with prostate cancer treated with IMRT at Memorial Sloan-Kettering Cancer Center were classified into prognostic risk groups. After an average of eight years, 89 percent of........Go to the Prostate-cancer-blog (Added on 9/27/2006 6:47:00 PM)
Investigational Anti-cancer Drug AT9283Astex Therapeutics today announced that it had begun dosing first patients in a Phase I/IIa clinical trial of its investigational anti-cancer drug AT9283. Astex discovered AT9283, a potent inhibitor of Aurora kinases, using its innovative fragment-based drug discovery technology, Pyramid-.
This is Astex's second product to enter clinical development. The company's lead product, AT7519, is already in a Phase I trial at sites in the US and the........Go to the Cancer-blog (Added on 9/26/2006 7:38:34 PM)
Bacterial Protein To Treat Intestinal ParasitesResearchers at the University of California, San Diego and Yale University have discovered that a natural protein produced by Bacillus thuringiensis, a bacterium sprayed on crops by organic farmers to reduce insect damage, is highly effective at treating hookworm infections in laboratory animals.
Their discovery, detailed in this week's early online edition of the Proceedings of the National Academy of Sciences, could pave the way for the........Go to the Infectious disease blog (Added on 9/25/2006 10:10:17 PM)
Laser probe may offer insight into Parkinson's diseaseIn a finding that may offer clues about Parkinson's disease, a team led by Duke University researchers used a sophisticated laser system to gain evidence that a dark brown pigment that accumulates in people's brains consists of layers of two other pigments commonly found in hair.
Other scientists previously had determined via chemical analysis that the dark pigment, called neuromelanin, is composed of the two pigments: eumelanin, found in........Go to the Neurology news blog (Added on 9/25/2006 9:46:53 PM)
Fampridine-sr Study For Multiple SclerosisAcorda Therapeutics, Inc. today announced positive results from its Phase 3 clinical trial of Fampridine-SR on walking in people with multiple sclerosis (MS). Statistical significance was achieved on all three efficacy criteria defined in the Special Protocol Assessment (SPA) by the Food and Drug Administration (FDA). A significantly greater proportion of people taking Fampridine-SR had a consistent improvement in walking speed, the study's........Go to the Neurology news blog (Added on 9/25/2006 9:32:52 PM)
A Spy In The Intestinal CanalThe colonsope, whic is a medical device currently used for intestinal research, causes patients great discomfort. At TU Delft, an alternative method has been developed, inspired by the way in which snails move. Researcher Dimitra Dodou received her PhD degree from TU Delft based on this research subject.
The intestines are an extremely difficult area to navigate through with a medical device. Yet, a number of people need to have intestinal........Go to the GI news blog (Added on 9/25/2006 5:47:51 PM)
What's The Best Strategy For Follow Up Of An Abnormality?You might be getting your regular mammogram follow ups, and some of you might get an abnormal result on the mammogram. You might be worried, quite understandable, but mammogram abnormality does not mean breast cancer. More important, now what should you do if the mammogram detects an abnormality?
Experts in the field indicate that if an abnormality is detected in the mammogram performing a breast biopsy is the best strategy, for follow up of........Go to the Breast-cancer-blog (Added on 9/25/2006 5:11:28 AM)
Hearing Loss From ChemotherapyChildren with cancer who suffer hearing loss due to the toxic effects of chemotherapy might one day be able to get their hearing back through pharmacological and gene treatment, thanks to work done with mouse models at St. Jude Children's Research Hospital. Mice with a variety of genetic mutations that disrupt different parts of the ear will also help researchers understand age-related hearing loss in adults, as well as hearing loss caused by........Go to the Cancer-blog (Added on 9/24/2006 10:27:17 PM)
Diabetes Not ObesityDiabetes puts people who are at risk of developing critical illness and dying early, but obesity without diabetes does not. A study published recently in the open access journal Critical Care reveals that individuals suffering from diabetes are three times more at risk of developing critical illness and dying young than individuals who do not have diabetes. Obese individuals who do not have diabetes, by contrast, have the same risk of dying or........Go to the Diabetic news blog (Added on 9/24/2006 9:50:51 PM)
Chronic Pain After Breast Cancer SurgeryA woman's young age, extensive surgery, and whether she suffered severe, post-operative pain are risk factors for developing chronic pain after breast cancer surgery, a University of Rochester study found.
Up to half of all women who undergo a lumpectomy or mastectomy feel pain weeks or months later near the breast, adjacent armpit and upper arm on the same side. It is often described as burning, throbbing, and/or a sharp pain.
As per a........Go to the Breast-cancer-blog (Added on 9/23/2006 11:44:01 AM)
Diverticulitis Now Seen In Young, Obese AdultsThis used to be a disease of older people who are more than 50 years old. Now this this is appearing in younger adults, who are obese. A research study from the University of Maryland Medical Center showed that diverticulitis is now occurring in younger adults who are obese.
"Over the last ten years, I noted that a number of patients coming into the emergency room with CT findings of acute diverticulitis seemed younger than traditional........Go to the GI news blog (Added on 9/22/2006 4:31:58 PM)
Skeletal Microdamage Stable After First YearSkeletal microdamage resulting from bisphosphonate therapy may be maximal during the first year of therapy, and not continue to accumulate with longer periods of therapy, as per new research being presented today at the 28th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR).
Bisphosphonates are the most common class of drugs used for the therapy of osteoporosis because of their demonstrated effect on fracture........Go to the Rheumatology news blog (Added on 9/20/2006 9:54:23 PM)
NSAIDs and GI complicationsNonsteroidal anti-inflammatory drugs (NSAIDs) provide a broad range of benefits for patients who require their use, but health care providers need to carefully consider the associated risks before prescribing these drugs for their patients, as per a multi-disciplinary panel of experts convened by the AGA Institute. Gastrointestinal (GI) morbidities are the most common adverse events linked to NSAID use, including complications in both the........Go to the GI news blog (Added on 9/20/2006 9:47:52 PM)
Higher Suicide Rate Among Women With Breast ImplantsDoes women with breast implants have a higher mortality rate? This was the question the researchers were asking, but they came up with a surprising finding. In study that evaluated 24,600 women by the Canadian Public Health Agency and Cancer Care Ontario found that having breast implants does not increase mortality risk. However, the study found that the suicide rate among women with breast implants is 73% higher than in the general........Go to the Breast-cancer-blog (Added on 9/20/2006 4:57:43 AM)
A spicy solution for colon cancer?A spicy turmeric solution for colon cancer.
In the last few years, that tactic has proved productive for scientists investigating turmeric, a curry spice used for centuries in Indian traditional medicine.
They've observed that turmeric's active ingredient, curcumin, works in the lab to fight skin, breast and other tumor cells. In fact, human clinical trials employing curcumin have already been launched.
Now, working with cell cultures........Go to the Colon-cancer-blog (Added on 9/19/2006 10:01:53 PM)