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Feb 13, 2006

Diabetes Can Lead To Gum Disease In Childhood

Diabetes Can Lead To Gum Disease In Childhood
Researchers from Columbia University Medical Center has shown that the destruction of the gums can start in diabetic children as young as six years old. While the link between diabetes and periodontal disease was previously established, it was believed that the regression of gums began much later and increased with age.

The study, a collaboration among researchers at the Columbia University College of Dental Medicine, Mailman School of Public Health and Naomi Berrie Diabetes Center, is published in the February issue of Diabetes Care.

"Our research illustrates that programs to prevent and treat periodontal disease should be considered a standard of care for young patients with diabetes," said Ira B. Lamster, D.D.S, M.M.Sc., dean of the College of Dental Medicine and principal investigator on the study, which is funded by the National Institute of Dental and Craniofacial Research.

"Other studies have shown that patients with diabetes are significantly less likely than those without diabetes to have seen a dentist within the past year," said Robin Goland, M.D., co-director of the Naomi Berrie Diabetes Center and a co-author of the paper. "This was due to a perceived lack of need, so clearly it's important that physicians and dentists and their patients with diabetes learn that they need to focus extra attention on oral health."

Oral health screenings are offered to all pediatric patients between the ages of 6 and 18 at the Naomi Berrie Diabetes Center, New York City's only comprehensive center for diabetes treatment, education and research.

The Columbia study clinically assessed dental cavities and periodontal disease in 182 children and adolescents, ages six to 18 years old, with diabetes, and 160 nondiabetic control subjects. The children with diabetes had significantly more dental plaque and more gingival inflammation than children without diabetes.

JoAnn      Permalink

Feb 10, 2006

Hormonal Therapy Of Prostate Cancer Could Be Lead To Diabetes, Heart Disease

Hormonal Therapy Of Prostate Cancer Could Be Lead To Diabetes, Heart Disease
Hormone therapy is the first best option for patients with recurrent prostate cancer. Hormone therapies is usually used to block testosterone production in an effort to halt or slow the growth of the tumor. New research suggests that hormone therapy may have its own toll. Hormone therapy may put these men at increased risk for developing insulin resistance and elevated blood sugar levels. This in turn can affect heart health.

Doctors say that hormone therapy may lead to high rate of heart disease in men with prostate cancer as per findings of this research published in the journal Cancer.

Dr. Shehzad Basaria from Johns Hopkins University say that heart disease is one of the most common causes of death in men with prostate cancer. In a study of 53 men with prostate cancer, the researchers found that those treated with hormonal therapy for at least one year were more resistant to the action of insulin, and had higher glucose levels than men who had only received local surgery and or radiation and had normal testosterone levels, and age-matched healthy men with normal testosterone levels.

According to the study, 44 percent of men in the hormone therapy group had blood sugar levels greater than 126, which is among the criteria for the diagnosis of diabetes. In contrast, only about 12 percent of men in the other groups had blood sugar levels this high.

Mark      Permalink

Feb 9, 2006

Eat More Whole Grains To Reduce Risk Of Diabetes

Eat More Whole Grains To Reduce Risk Of Diabetes
A new study published in the January issue of American Journal of Clinical Nutrition, researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (HNRCA) found that consuming a diet rich in whole-grain foods may lower an elderly person's risk for cardiovascular disease and reduce the onset of metabolic syndrome and diabetes. The term metabolic syndrome is used for a collection of risk factors, puts people at an increased risk of cardiovascular disease and type-2 diabetes.

This study was led by Paul Jacques, DSc, director of the Nutritional Epidemiology Program at the HNRCA. Jacques and his colleagues examined the relationship between whole-grain intake and cardiovascular disease risk factors, metabolic syndrome, and the incidence of death due to cardiovascular disease in the elderly.

The study has shown that consuming a high whole-grain diet is likely to have positive metabolic effects in elderly individuals, who are prone to greater insulin resistance and impaired glucose tolerance.

Researchers showed that, as whole-grain intake increased, fasting blood sugar levels were lower in study subjects. Refined grain intake, on the other hand, was associated with higher fasting blood sugar levels. Elevated fasting blood sugar levels can indicate impaired glucose tolerance and the presence of diabetes. In addition, people who consumed high amounts of refined grains had twice the risk of having metabolic syndrome than those people who consumed the fewest servings of refined grains.

JoAnn      Permalink

Feb 6, 2006

Diabetes Drugs May Increase Risk Of Cancer Death

Diabetes Drugs May Increase Risk Of Cancer Death
Drugs that are commonly used in type-2 diabetes may increase the risk of cancer as per findings from new research. Many patients with type 2 diabetes who take sulfonylureas or insulin appear to be at increased risk of dying from cancer compared with those who take metformin, as per Canadian researchers.

However, researchers say that their study is in the early stage, and it is still uncertain whether the increased risks of cancer-related mortality that were observed are related to a protective effect of metformin or deleterious effects of sulfonylurea and insulin.

Johnson and colleagues said that numerous studies have suggested an association between type-2 diabetes and cancer.

The so-called sulfonylureas increases production of insulin, while the drug metformin makes the body's existing stores of insulin more effective.

The study included 10,300 new users of metformin or sulfonylureas. Their average age was 63.

After adjustment for several factors, users of a sulfonylurea or insulin had a higher risk of cancer-related mortality than metformin users.

JoAnn      Permalink

Feb 2, 2006

Fda Approves Inhaled Insulin

Fda Approves Inhaled Insulin
Exubera, becomes the first FDA approved inhaled form of insulin opening the gateway for freedom from needles. This is a long awaited approval by the Food and Drug administration agency, and may open a totally new world for millions of diabetics who now only on inject able forms of insulin.

Diabetics all over America can now dream of a world free of countless injections that have been dictating their lives.

"This is the first new insulin delivery option introduced since the discovery of this drug in 1920s," said Dr. Steve Galson, director of the FDA Center for Drug Evaluation and Research. "There are more than 5 million Americans who take insulin injections every day, and Exubera may be an option for many of these patients. It will not replace all injectable insulin. . . It's a very highly innovative product that has the potential to improve the quality of life of millions of Americans with diabetes."

"This is highly positive. It will be a major advance for individuals with diabetes, both children and adults," said Dr. Robert Rapaport, director of the division of pediatric endocrinology at Mount Sinai School of Medicine in New York City. "I think there will be some longstanding questions about its ultimate safety because it's the first inhaled medication that will be used like this. But, assuming the safety profile will be good, it will be a major advance."

This approval by FDA closely followed European regulators' approval of Exubera on recently.

JoAnn      Permalink

Jan 31, 2006

Imaging For Brain Changes In Patients With Diabetes

Imaging For Brain Changes In Patients With Diabetes
Although people with diabetes are twice as likely as the general population to develop depression, the cause of this increased risk is not well understood. Now, a Joslin Diabetes Center-led collaboration has documented for the first time subtle changes in the gray matter of the brain of type 1 diabetes patients compared to control subjects who did not have diabetes. They made these observations using voxel-based morphometry (VBM), a relatively new magnetic resonance imaging (MRI) technology that allows researchers to take very sensitive measurements of small regions in the brain. For the first time, doctors have reason to ask if the increased risk of depression could in fact be due to changes in brain.

"We have known for a long time that diabetes can damage the nerves that control the extremities and those that control internal organs like the heart and the intestine," says the study's principal investigator, Alan M. Jacobson, M.D., head of Behavioral and Mental Health Research at Joslin Diabetes Center. "This research helps document diabetes-related changes to the central nervous system. People tended to assume that the stress of dealing with a severe chronic illness and its complications was the sole source of depression. That still is an important issue, but now we have evidence that something else might be at work."

Equally important, by showing the effectiveness of VBM for observing and evaluating changes in brain structure that appear to be related to diabetes, the study opens up whole new approaches to understanding the central nervous system in diabetes. This technology creates three-dimensional images of magnetic resonance imaging data, which researchers can then use to observe and evaluate structural changes, in this case, in the brain.

"We've used this technology to look at patients with bipolar disorder or with classic neurodegenerative disorders, but this is the first study to use VBM to investigate brain changes in patients with diabetes," says co-investigator Perry Renshaw, M.D., Ph.D., who directs the Brain Imaging Center at McLean Hospital in Belmont, Mass.

JoAnn      Permalink

Jan 24, 2006

Teach Your Children Good Eating Habits Early

Teach Your Children Good Eating Habits Early
About 21 million Americans are suffering from diabetes and in addition there are 45 million prediabetics in America. The Centers for Disease Control and Prevention estimate that one out of every three children born in the United States will develop this fatal malady during the course of their life.

I know, you are aware of the complications associated with diabetes. Diabetes increases the risk of heart attacks, stroke, kidney failure, blindness, loss of circulation leading to gangrene and amputation of feet, legs and hands. Diabetes damages the nervous system, leaving people in continuous, excruciating pain, and it decreases their immunity, whereby making them more susceptible to infection.

It is important to realize that this killer disease is largely preventable. It is important that you recognize the most important factor that leads to development of diabetes. Obesity is the number one cause for development of diabetes. There is no scarcity for food for people living in America even among low-income groups. The combination of factory-made food loaded with the grease and in combination with lack of exercise is driving millions of Americans in to the no return path of diabetes and heart disease.

Look at the children, at home and at school children are habituated to eating what will make them overweight. Adults play a large role in developing such unhealthy habits in your children. When was the last time you took you children to the high grease fast food chain store? Was it yesterday? Was it day before?

There are regulations in place for advertising in public media in Australia, Canada and England. In the United States, which is the land of free speech our children are exposed to thousands of cunning ads to entice them to embrace into this poor eating habits.

Once children learn such bad eating habits, it's very difficult to change these habits. So it is better to try it now before it's too late. Teach them the values of healthy food and exercise and they will thank you for this.

JoAnn      Permalink

Jan 23, 2006

Don't Count On Veggie Burgers Or Toufu

Don't Count On Veggie Burgers Or Toufu
Do not count on Veggie burgers and tofu to protect you from heart disease. A recent American Heart Association committee review report examined studies spanning over a decade and came up with doubts regarding the claim that soy-based foods and supplements are effective in significantly lowering cholesterol.

These findings are contrary to popular believes and may lead to label regulations regarding this claim on soy containing food by FDA.

This study panel also found that neither soy nor the soy component isoflavone reduced symptoms of menopause, such as ``hot flashes,'' and that isoflavones do not help prevent breast, uterine or prostate cancer. When examining the effects of soy on bone mineral loss in post-menopausal women, the studies showed mixed results. These findings are published in the recent issue of circulation.

However this does not mean that eating soy based food is not good. Often soy-based food is consumed in place of junk food, like burgers and hotdogs and consumption of soy-based food may at least prevent the harmful effects of eating unhealthy food. The only finding that has come out now is that it may not be as beneficial as previously thought especially in terms of cholesterol lowering.

``We don't want to lull people into a false sense of security that by eating soy they can solve the problem'' with cholesterol, said Dr. Michael Crawford, chief of clinical cardiology at University of California-San Francisco Medical Center. He was not on the panel that issued the new statement.

The FDA in 1999 started allowing manufacturers to claim that soy products might cut the risk of heart disease by lowering cholesterol level after studies showed at least 25 grams of soy protein a day lowered cholesterol. A year later, the Heart Association recommended in favor of soy to classify this as a diet low in saturated fat and cholesterol.

In the last few years much more research emerged and the Heart Association decided to re-investigate this issue.

These committee members reviewed 22 studies and found that large amounts of dietary soy protein only reduced LDL, or ``bad'' cholesterol, about 3 percent and had no effect on HDL, or ``good'' cholesterol, or on blood pressure.

They also did analysis of isoflavones separately and found that isoflavones also had no effect on lowering LDL cholesterol or other lipid risk factors.

``Soy proteins and isoflavones don't have any major health benefits other than soy protein products are generally good foods,'' said Dr. Frank Sacks, a professor of nutrition at the Harvard School of Public Health in Boston who led the committee.`They're good to replace other foods that are high in cholesterol.''

Sherin      Permalink

Jan 20, 2006

Stress At Work And Risk Of Heart Disease

Stress At Work And Risk Of Heart Disease
Stress and burnout at work place causes several health related problems

Cardiovascular Disease
Many studies suggest that psychologically demanding jobs that allow employees little control over the work process increase the risk of cardiovascular disease.

Musculoskeletal Disorders
On the basis of research by NIOSH and many other organizations, it is widely believed that job stress increases the risk for development of back and upper- extremity musculoskeletal disorders.

Psychological Disorders
Several studies suggest that differences in rates of mental health problems (such as depression and burnout) for various occupations are due partly to differences in job stress levels. (Economic and lifestyle differences between occupations may also contribute to some of these problems.)

Workplace Injury
Although more study is needed, there is a growing concern that stressful working conditions interfere with safe work practices and set the stage for injuries at work.

Suicide, Cancer, Ulcers, and Impaired Immune Function
Some studies suggest a relationship between stressful working conditions and these health problems. However, more research is needed before firm conclusions can be drawn.

Scientists in Britain said on Friday they had found evidence of why stress at work can raise the odds of developing heart disease and diabetes.

Researchers at University College London (UCL) have shown that work stress is a risk factor for metabolic syndrome which includes high blood pressure, raised cholesterol levels, high blood sugar and excess weight.

"We found quite strong evidence that higher exposure to stress at work is associated with increased risk of the metabolic syndrome," said Tarani Chandola of UCL.

Researchers say that the study provides a possible explanation for the link between stress and heart disease.

In the study of more than 10,000 British civil servants published online by the British Medical Journal the scientists said the higher the stress levels reported by the employees the greater the risk of metabolic syndrome.

The scientists studied the stress levels of the civil servants over the past 20 years and compared them with components of metabolic syndrome which were measured between 1997 and 1999.

Men with chronic work stress were nearly twice as likely to develop the syndrome than workers who reported little or no stress, according to the study.

Daniel      Permalink

Jan 18, 2006

The Diabetes Colon Cancer Connection

The Diabetes Colon Cancer Connection Beautiful night view of Singapore
Diabetes may be linked to increased risk of developing colon cancer. It has been shown in the Western population that the presence of diabetes is associated with an increased risk of colorectal cancer, and now there is more evidence from the east. A new study done in Chinese population residing in Singapore has just shown the same result.

Ethnic group of Chinese population living in Singapore was selected for this study because, the body type and lifestyle of residents are different from people living in Western countries. Chinese population in this area tends to be lean and less heavy compared to the western population. Dr. Adeline Seow, from the National University of Singapore, and colleagues led this study which showed a link between diabetes and colorectal cancer.

This study involves more than 60,000 people, and the results are published in the Journal of the National Cancer Institute. These participating subjects provided detailed dietary, medical, and lifestyle information and then were followed for several years to assess the occurrence of colorectal cancer and related risk factors.

In this study population of 60,000 people a total of 636 cases of colorectal cancer occurred during follow-up. When the researchers analyzed these results in detail, they found that a subset of men and women with a history of diabetes were 50 and 40 percent, respectively, more likely to develop colorectal cancer than their peers without diabetes.

Sherin      Permalink

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Type-2 Diabetes
Type-2 diabetes is the most common form of diabetes, accounting for 90% of cases diabetes. This disease affects nearly 17 million Americans and is the seventh leading cause of death in the United States. Even though 17 million Americans have type-2 diabetes only half of these people are aware that they have diabetes. The death rate in patients with diabetes may be up to 11 times higher than in persons without the disease. The occurrence of diabetes in persons 45 to 64 years of age is 7 percent, but the proportion increases significantly in persons 65 years of age or older. Type-2 diabetes accounts for more than 90% of all diabetes worldwide. Archives of diabetes-watch-blog

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