September 22, 2006, 4:32 PM CT
Diverticulitis Now Seen In Young, Obese Adults
This used to be a disease of older people who are more than 50 years old. Now this this is appearing in younger adults, who are obese. A research study from the University of Maryland Medical Center showed that diverticulitis is now occurring in younger adults who are obese.
"Over the last ten years, I noted that a number of patients coming into the emergency room with CT findings of acute diverticulitis seemed younger than traditional teaching suggested, and often were obese," said Barry Daly, MD, an author of the study partner in research. "We were seeing patients as young as their early twenties, though textbooks typically describe this condition as a disease of the over-fifty age group," he said.
Elderly adults often develop acute diverticulitis, and this is considered to be one of the most frequent acute diseases of the colon. This disease is thoughtful occur because of inadequate amount of fiber in the diet. A diet which is deficient in fiber causes numerous thin-walled out-pouches called diverticula to develop in the bowel wall. This is actually a chronic condition known as diverticulosis. With passage of time bacterial infection of these diverticula can occur and this would cause inflammation that may lead to a perforation in the wall of the intestine and other serious complications.........
Posted by: Sue Permalink Source
September 19, 2006, 10:06 PM CT
Too little fat! May not be the best thing
Too much body fat may be a bad thing, but there is increasing evidence that too little fat also may have some surprisingly negative consequences.
Scientists at UC Irvine have observed that fat droplets - tiny balls of fat that exist in most cells - appear to have an intriguing role to play when it comes to regulating excess proteins in the body. In a study with fruit flies, developmental biologist Steven Gross and his colleagues observed that these fat droplets served as storage depots for a type of protein used primarily by the cell to bind DNA and organize it in the nucleus. The fat keeps this extra protein out of the way until it is needed so that it does not cause harm within the cell. The findings imply that fat droplets could also serve as storage warehouses for other excess proteins that might otherwise cause harm if not sequestered. The study appears in the current issue of Current Biology.
"We were surprised to find that these droplets appear to be a mechanism for cleaning up excess proteins before they cause trouble," said Gross, associate professor of developmental and cell biology. "Obviously, everything in the body should be balanced. There is no doubt that huge amounts of fat tax your system in a lot of ways. But there now appears to be growing evidence that fat is also important for keeping us healthy".........
Posted by: Scott Permalink Source
September 18, 2006, 9:30 PM CT
A Mother Prompting Her Child To Eat And Obesity?
The prevalence of childhood obesity has increased significantly since the 1980s. A number of factors contribute to childhood obesity; however, parents are in a key position to help shape children's eating behaviors and eating environments. A study in the recent issue of The Journal of Pediatrics evaluates the role of mothers prompting their child to eat, the child's compliance with those prompts, and the potential contribution of each to the risk of obesity.
Dr. Julie Lumeng and Ms. Lori Burke from the University of Michigan videotaped and reviewed the tasting of four different foods by 71 mother-child pairs. Two of the foods presented were familiar (a cream-filled sponge cake and potato chips) and two were unfamiliar (a sweet Chinese dessert cake and fried vegetable chips). The scientists recorded how a number of times the mother prompted her child to take a bite and whether the child obeyed these prompts. On average, children complied with their mother's prompts to take another bite approximately two-thirds of the time.
Low maternal education, the presentation of unfamiliar foods, and younger age of the child were factors that predicted more prompting from the mother. Conversely, the mother being obese, the offering of familiar foods, and older age of the child were factors that predicted the child's compliance with the prompts. In children of obese mothers, variables that predicted a higher body mass index in the child were low maternal education, more prompts by the mother to eat unfamiliar foods, and fewer prompts to eat and bites of the familiar foods. In contrast, in children of mothers who were not obese, none of these behaviors were correlation to the child's weight status.........
Posted by: JoAnn Permalink Source
September 18, 2006, 4:49 AM CT
Want to lose weight? Be a SMART planner
OK. Recently you have made a decision to get some unwanted pounds from your body. And you have a plan and motivation to actually implement this brave idea. The first thing regarding this nice idea is to become a very SMART planner.
SMART is actually an acronym (short form) which means being Specific, Measured, Appropriate, Realistic, and Time-bound about your cherished goal. For example, imagine that your plan is focused on increasing exercise, then the first thing you do is to jolt down the details of your workout plan. You have to be specific regarding your strategic plan. You should settle on precisely what kind of activity you are considering and write it down. Being SMART would mean that you are very much aware about all details of your master plan. In this example, you should be very clear about the fact, how many times you would be able to realistically perform the planned physical activity in each week. You are also assumed to have a clear idea as to the amount of time you would be spending on this physical activity during each session.
We are all poor performers when it comes to memorizing and maintaining to set patterns and schedules. It is important that you just don't keep your bright ideas in your brain since memories and your new year resolutions would fade with time. Moreover you are more willing to procrastinate schedules and resolutions that reside just in your brain. Create a calendar and mark a regular schedule of exercise corresponding to the time at your disposal. It is better to setup a regular and periodic physical activity plan. Always start with small, short, and easier goals, which you are likely to achieve, and then work your way up to your major goal with a feeling of achievement.........
Posted by: JoAnn Permalink
September 17, 2006, 10:24 PM CT
Dieting and Alzheimer's disease
A new study directed by Mount Sinai School of Medicine extends and strengthens the research that experimental dietary regimens might halt or even reverse symptoms of Alzheimer's Disease (AD). The study entitled "Calorie Restriction Attenuates Alzheimer's Disease Type Brain Amyloidosis in Squirrel Monkeys" which has been accepted for publication and would be reported in the November 2006 issue of the Journal of Alzheimer's Disease, demonstrates the potential beneficial role of calorie restriction in AD type brain neuropathology in non-human primates. Restricting caloric intake may prevent AD by triggering activity in the brain linked to longevity.
"The present study strengthens the possibility that CR may exert beneficial effects on delaying the onset of AD- amyloid brain neuropathology in humans, similar to that observed in squirrel monkey and rodent models of AD," reported Mount Sinai researcher Dr. Pasinetti and colleagues, who published their study, showing how restricting caloric intake based on a low-carbohydrate diet may prevent AD in an experimental mouse model, in the July 2006 issue of the Journal of Biological Chemistry.
"This new breakthrough brings great anticipation for further human study of caloric restriction, for AD researchers and for those physicians who treat millions of people suffering with this disease" says Giulio Maria Pasinetti, M.D., Ph.D., Professor of Psychiatry and Neuroscience, Director of the Neuroinflammation Research Center at Mount Sinai School of Medicine and lead author of the study. "The findings offer a glimmer of hope that there may someday be a way to prevent and stop this devastating disease in its tracks." .........
Posted by: Daniel Permalink Source
September 13, 2006, 9:01 PM CT
Dieting Female Athletes More Likely to Get Stress Fractures
Female college athletes on low-calorie diets could be putting themselves at risk for stress fractures, as per new Saint Louis University research published in this month's The American Journal of Sports Medicine.
Scientists studied risk factors for exercise-related leg pain, including stress fractures in women participating in four popular fall sports - cross-country running, field hockey, soccer and volleyball.
Women with "disordered eating," which includes eating disorders such as bulimia and anorexia but more generally refers to insufficient caloric intake, were more likely to develop stress fractures as a result of decreased estrogen production, says researcher Mark Reinking, PT, Ph.D., chairman of the department of physical treatment at Saint Louis University's Doisy College of Health Sciences.
"When people expend more calories than they consume, they release fewer hormones, which slows down menstrual cycles. This decreases estrogen in the body, which is responsible for bone development," says Reinking, also chairman of the American Board of Physical Therapy Specialties.
Leg pain is one of the most common problems afflicting athletes, Reinking says.
"It causes people to miss practices and competitions, and I wanted to understand if two people were undergoing the same exercise regime, why only one of them would have leg pain," he says. "It's not as simple as 'Run less' or 'Change your shoes every 300 miles.' It's a complex problem, and you can't prevent something if you don't know what causes it."........
Posted by: JoAnn Permalink Source
September 13, 2006, 5:03 AM CT
Added Benefit Of Statins
UC Davis scientists have shown that statins not only improve cholesterol levels, but also dramatically reduce disease-causing inflammation in patients with metabolic syndrome - a condition defined by symptoms that include abdominal obesity and high blood pressure.
The study, published online in the September 12 issue of the Journal of Clinical Endocrinology & Metabolism, offers new hope to the one in four Americans with metabolic syndrome who have double the risk of developing heart disease and are five times more likely to develop diabetes.
"Changes in diet and exercise, resulting in weight loss are still the therapy of choice for preventing the consequences of metabolic syndrome," said Kenny Jialal, a professor of internal medicine at UC Davis Health System and director of the Laboratory for Atherosclerosis and Metabolic Research. "However, people don't always adhere to those changes. Our results suggest that statin may be a way to forestall the deadly complications of metabolic syndrome".
Statins are a class of drugs used to prevent and treat heart disease. They work by lowering cholesterol levels and preventing atherosclerosis, the blockage of blood vessels due to plaque build-up. Previously, Jialal's group showed that statins, as a class of drugs, are anti-inflammatory. Typically since the metabolic syndrome, is characterized by low-grade inflammation and insulin resistance, they decided to look at the direct effect of statins on inflammation in these patients.........
Posted by: Daniel Permalink Source
September 13, 2006, 4:41 AM CT
Exercise Reduces Colon-cancer Risk
Regular, moderate-to-vigorous aerobic exercise significantly reduces a risk factor linked to the formation of colon polyps and colon cancer in men, as per a research studyled by scientists at Fred Hutchinson Cancer Research Center. The findings, from the first randomized clinical trial to test the effect of exercise on colon-cancer biomarkers in colon tissue, appear in the recent issue of Cancer Epidemiology, Biomarkers and Prevention.
"In men who met the study's exercise prescription of an hour of aerobic activity per day, six days a week for a year, we saw a substantial decrease in the amount of cellular proliferation in the areas of the colon that are most vulnerable to colon cancer," said lead author Anne McTiernan, M.D., Ph.D., an internist and epidemiologist who directs the Hutchinson Center's Prevention Center. "However, we observed that even four hours or more of exercise weekly was enough to produce a significant benefit," she said.
Specifically, the scientists saw a decrease in the number of actively dividing cells, or cellular proliferation, within the colonic crypts - tiny tube-like indentations in the lining of the colon, or epithelium, which help regulate the absorption of water and nutrients. "A certain amount of cellular proliferation at the bottom part of the crypt is normal. But when these cells start dividing too quickly, they can migrate up the sides of the crypt to the surface and eventually form a polyp," she said. While most polyps are benign, over time some types can become cancerous.........
Posted by: Janet Permalink Source
September 12, 2006, 5:04 AM CT
Weight-loss Rate Doubles Before Dementia
A long-term study of the elderly has revealed that their average rate of weight loss doubles in the year before symptoms of Alzheimer's-type dementia first become detectable. The finding may be useful to scientists seeking ways to detect and treat Alzheimer's before it causes irreversible brain damage.
The study is the first to confirm in precise detail a link between weight loss and dementia tentatively identified a decade ago. Scientists report in the September 2006 Archives of Neurology that one year before study volunteers were diagnosed with very mild dementia, their rate of weight loss doubled from 0.6 pounds per year to 1.2 pounds per year. The analysis used data from the Memory and Aging Project at the Alzheimer's Disease Research Center (ADRC) of Washington University School of Medicine in St. Louis.
Alzheimer's scientists are working hard to find biomarkers, indicators that can be used to detect the presence of Alzheimer's before clinical symptoms become obvious. Studies at the ADRC and elsewhere have strongly suggested that if Alzheimer's therapys will ever prevent lasting cognitive damage, they may have to be given to patients before memory loss and other disruptions caused by the disorder are evident.
"A person's weight can vary substantially in a given year, so weight loss alone can't serve as a definite indicator for physicians," says David K. Johnson, Ph.D., research instructor in neurology. "But it's interesting from a biochemical perspective--we don't know why these two phenomena are linked. And weight loss may one day be incorporated into a battery of biomarkers that physicians keep their eyes on for early warning of Alzheimer's-type dementia".........
Posted by: JoAnn Permalink Source
September 5, 2006, 10:05 PM CT
Identifying risk for obesity in early childhood
A new research study of children's growth, reported in the recent issue of Pediatrics, can help parents and pediatricians determine the risk that a child will be overweight at age 12 by examining the child's earlier growth. The study demonstrates that children who are overweight at any stage of their growth before age 12 are more likely to be overweight by the time they are 12, and the more times a child is measured as overweight during these growth years, the greater the chance that by 12 the child will be overweight.
For example, the scientists discovered that preschool-age children who were medically determined to be overweight at one of three points of measurement before age 5 were more than five times as likely to be overweight at age 12 than those who were below the 85th percentile for body mass index (BMI) during the same period. BMI is a standard measure calculated from a person's height and weight.
Philip R. Nader, M.D., Professor Emeritus of Pediatrics at the University of California, San Diego (UCSD) School of Medicine, is primary author of the study, with co-authors from 10 different institutions around the nation. He said the group pursued the study because obesity is a major public health problem in the United States.
As per Center for Disease Control growth standards developed before the obesity epidemic, children are considered to be overweight if their BMI is over the 85th percentile, or falls in the top 15% of children of the same height and gender. The Institute of Medicine considers these children obese if their BMI is over the 95tth percentile or the top 5%. The rate of obesity among adults and children in the U.S. has nearly tripled over the time that the children in the study were growing up.........
Posted by: JoAnn Permalink Source