From Medicineworld.org: Drugs causing thrombocytopenia or low platelet count
Drugs causing thrombocytopenia or low platelet count
By Kottapurath Kunjumoideen MD
Immune thrombocytopenia (ITP) is a commonest blood disorder that causes thrombocytopenia or low platelet count. Apart from ITP, many drugs can cause thrombocytopenia. Some drugs like anticancer drugs and valproic acid causes dose depended decrease in the number of platelets by myelosuppression. Drugs may also cause thrombocytopenia by immunological mechanisms. Immunological drug induced thrombocytopenia can be caused by the following two mechanisms.
(anti-neoplastic drugs are not included)
Did you know?
Immune thrombocytopenic purpupura otherwise known as idiopathic thrombocytopenic purura (ITP) is a blood disorder in which your own platelets are destroyed by antibodies directed against them. The word immune means that the thrombocytopenia or low platelet count results from immune system's involvement in this disorder. Since blood platelets are involved in stoppage of bleeding, ITP blood disorder may be associated with bleeding. The term purpura refers to the purplish-looking spots of the skin and mucous membranes (such as the lining of the mouth) where bleeding has already occurred as a result of decreased platelet. ITP usually occurs in women and may happen as one episode, or several episodes. ITP may occur as a complication of pregnancy.
Medicineworld.org: Drugs causing thrombocytopenia or low platelet count
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