MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Organic substance may help heal broken hearts

Back to heart watch blog Blogs list Cancer blog  


Subscribe To Heart Watch Blog RSS Feed  RSS content feed What is RSS feed?

Organic substance may help heal broken hearts




Imagine new therapys for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition. That's not hard to do thanks to Canadian researchers, who for the first time, have developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online in The FASEB Journal (http://www.fasebj.org) is a major step toward therapys that allow people to more fully recover from injury and disease rather than having to live with chronic health problems. It may even help reduce the need for organ transplantation by allowing physicians to save organs that would have been previously damaged beyond repair.



organic substance may help heal broken hearts

The "smart scaffolds," developed by Erik Suuronen and colleagues from the University of Ottawa and the Ottawa Heart Research Institute, work because they contain a protein that allows progenitor cells to adhere to the damaged tissue and survive long enough to promote healing. These cells emit homing signals that summon other cells to join in the process and give off chemical signals that order cells to grow blood vessels necessary for healing to occur.

"Ultimately, we envision a scaffold material that can be taken off the shelf and injected into the hearts of patients suffering from blocked arteries," said Suuronen. "The scaffold materials would direct the repair process, and restore blood flow and function to the heart".

The scientists tested this material in three groups of rats, with each group suffering from a lack of blood oxygen (ischemia) to their thigh muscles. The muscles in the first group of rats were treated with the smart scaffold. The second group of rats received a scaffold not engineered for cell attachment. The third group received a placebo. Two weeks after therapy, rats treated with the "smart" scaffold had more new blood vessels and better functional recovery while rats from the other two groups of rats only had minimal improvement.

"This is a major development toward radically new therapys for heart and muscle disease," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal "If this research holds up in humans, it has the potential to save more lives than any other major advance in the field since the stent".


Posted by: Daniel    Source




Did you know?
Imagine new therapys for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition. That's not hard to do thanks to Canadian researchers, who for the first time, have developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online in The FASEB Journal (http://www.fasebj.org) is a major step toward therapys that allow people to more fully recover from injury and disease rather than having to live with chronic health problems. It may even help reduce the need for organ transplantation by allowing physicians to save organs that would have been previously damaged beyond repair.

Medicineworld.org: Organic substance may help heal broken hearts

Main Page| Cancer blog| Cancer blogs list| Lung cancer blog| Colon cancer blog| Prostate cancer blog| Breast cancer blog| Diabetes watch blog| Heart watch blog| Allergy blog| Bladder cancer blog| Cervical cancer blog| Colon cancer news blog| Diabetes news blog| Esophageal cancer blog| Gastric cancer blog| Health news blog| Heart news blog| Infectious disease blog| Kidney watch blog| Lung disease blog| Lung cancer news blog| Mesothelioma blog| Neurology blog| Breast cancer news blog| OBGYN blog| Ophthalmology blog| Ovarian cancer blog| Cancer news blog| Pancreas cancer blog| Pediatrics blog| Prostate cancer news blog| Psychology blog| Research blog| Rheumatology blog| Society news blog| Uterine cancer blog| Weight watch blog|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.