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Medicineworld.org: Ffat mass helps build bone mass in girls

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Ffat mass helps build bone mass in girls




As per a newly released study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), fat mass is important in increasing bone size and thickness, but this effect may be stronger in girls than boys.

Lean mass is one of the strongest determinants of bone mass throughout life. Until now, it has been unclear whether fat mass and lean mass differ in how they influence bone development in boys and girls. Findings from prior studies have been inconsistent regarding whether fat mass has a positive or negative impact on bone development. This newly released study shows that fat mass is a strong stimulus for the accrual of cortical bone mass (hard outer layer of bone) in girls.



Ffat mass helps build bone mass in girls

In this study, scientists used dual x-ray absorptiometry (DXA) to determine total body fat mass and lean mass, and peripheral quantitative computer tomography (pQCT) to measure cortical bone mass at the mid-tibia, in 4,005 boys and girls with a mean age of 15.5 years. Eventhough lean mass was the major determinant of bone mass, fat mass also exerted an important positive influence, especially in girls, in which the effect was approximately 70 percent greater than in boys.

"The effect of fat mass on bone mass may be strongest in girls," said Jonathan Tobias, PhD, of the University of Bristol in the United Kingdom, and main author of the study. "Girls clearly have more fat mass than boys and our findings show that whereas the greater lean mass in boys contributes to their greater cortical bone mass, this effect is partly counteracted by the greater fat mass in girls".

"Fat mass in girls during puberty may have a long-term impact on bone health as they grow into adulthood," said Tobias. "Excessive reduction in fat mass could have adverse effects on the developing skeleton especially in girls, leading to an increased risk of osteoporosis in later life".

Adrian Sayers of the University of Bristol in the United Kingdom also worked on this study.


Posted by: JoAnn    Source




Did you know?
As per a newly released study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM), fat mass is important in increasing bone size and thickness, but this effect may be stronger in girls than boys. Lean mass is one of the strongest determinants of bone mass throughout life. Until now, it has been unclear whether fat mass and lean mass differ in how they influence bone development in boys and girls. Findings from prior studies have been inconsistent regarding whether fat mass has a positive or negative impact on bone development. This newly released study shows that fat mass is a strong stimulus for the accrual of cortical bone mass (hard outer layer of bone) in girls.

Medicineworld.org: Ffat mass helps build bone mass in girls

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