MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Genetic test to predict early menopause

Back to obgyn news Blogs list Cancer blog  


Subscribe To Obgyn News RSS Feed  RSS content feed What is RSS feed?

Genetic test to predict early menopause




The first research from the Breakthrough Generations Study could lead to a test to predict a woman's reproductive lifespan.

The findings, published recently in Human Molecular Genetics, could have considerable impact on women in the UK and other western countries, where a number of start having children at a later age. Early menopause affects one in 20 UK women.



Genetic test to predict early menopause

The study from researchers at the University of Exeter Peninsula Medical School and The Institute of Cancer Research (ICR), funded by The Wellcome Trust, tested four genes linked to the menopause. They compared 2,000 women from the Breakthrough Generations Study who had experienced early menopause with a matched group of the same number. The four genes each affected risk of early menopause. In combination, they had a larger impact, which goes towards explaining why some women experience early menopause.

The Breakthrough Generations Study is a large and comprehensive study into the causes of breast cancer and a partnership between Breakthrough Breast Cancer and the ICR. The study will follow the 100,000 UK women participants for the next 40 years to unravel the lifestyle, environmental and genetic factors that cause the disease.

Eventhough early menopause is linked to a decreased risk of breast cancer, women who experience early menopause are susceptible to other health problems including osteoporosis, cardiovascular disease and a reduction in fertility.

The research could help women determine whether they have a genetic predisposition to early menopause, and therefore predict the time of the end of their reproductive life. They could then make informed family planning decisions on the basis of this knowledge.

Lead scientist Dr Anna Murray, from the University of Exeter Peninsula Medical School, says, "It is estimated that a woman's ability to conceive decreases on average ten years before she starts the menopause. Therefore, those who are destined to have an early menopause and delay childbearing until their 30s are more likely to have problems conceiving.

"These findings are the first stage in developing an easy and relatively inexpensive genetic test which could help the one in 20 UK women who appears to be affected by early menopause".


Posted by: Emily    Source




Did you know?
The first research from the Breakthrough Generations Study could lead to a test to predict a woman's reproductive lifespan. The findings, published recently in Human Molecular Genetics, could have considerable impact on women in the UK and other western countries, where a number of start having children at a later age. Early menopause affects one in 20 UK women.

Medicineworld.org: Genetic test to predict early menopause

Asthma| Hypertension| Medicine Main| Diab french| Diabetes drug info| DruginfoFrench| Type2 diabetes| Create a dust free bedroom| Allergy statistics| Cancer terms| History of cancer| Imaging techniques| Cancer Main| Bladder cancer news| Cervix cancer news| Colon cancer news| Esophageal cancer news| Gastric cancer news| Health news| Lung cancer news| Breast cancer news| Ovarian cancer news| Cancer news|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.