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Medicineworld.org: Vitamin D deficiency and cardiovascular disease

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Vitamin D deficiency and cardiovascular disease




While mothers have known that feeding their kids milk builds strong bones, a newly released study by scientists at the Heart Institute at Intermountain Medical Center in Salt Lake City suggests that Vitamin D contributes to a strong and healthy heart as well and that inadequate levels of the vitamin may significantly increase a person's risk of stroke, heart disease, and death, even among people who've never had heart disease.



Vitamin D deficiency and cardiovascular disease

For more than a year, the Intermountain Medical Center research team followed 27,686 patients who were 50 years of age or older with no previous history of cardiovascular disease. The participants had their blood Vitamin D levels tested during routine clinical care. The patients were divided into three groups based on their Vitamin D levels normal (over 30 nanograms per milliliter), low (15-30 ng/ml), or very low (less than 15 ng/ml). The patients were then followed to see if they developed some form of heart disease.

Scientists observed that patients with very low levels of Vitamin D were 77 percent more likely to die, 45 percent more likely to develop coronary artery disease, and 78 percent were more likely to have a stroke than patients with normal levels. Patients with very low levels of Vitamin D were also twice as likely to develop heart failure than those with normal Vitamin D levels.

Findings from the study will be presented at the American Heart Association's Scientific Conference on Monday, Nov. 16 in Orlando, Florida.

"This was a unique study because the association between Vitamin D deficiency and cardiovascular disease has not been well-established," says Brent Muhlestein, MD, director of cardiovascular research of the Heart Institute at Intermountain Medical Center and one of the authors of the newly released study. "Its conclusions about how we can prevent disease and provide therapy may ultimately help us save more lives".

A wealth of research has already shown that Vitamin D is involved in the body's regulation of calcium, which strengthens bones and as a result, its deficiency is linked to musculoskeletal disorders. Recently, studies have also linked Vitamin D to the regulation of a number of other bodily functions including blood pressure, glucose control, and inflammation, all of which are important risk factors correlation to heart disease. From these results, researchers have postulated that Vitamin D deficiency may also be associated with heart disease itself.

"Utah's population gave us a unique pool of patients whose health histories are different than patients in prior studies," Dr. Muhlestein says. "For example, because of Utah's low use of tobacco and alcohol, we were able to narrow the focus of the study to the effects of Vitamin D on the cardiovascular system." .

The results were quite surprising and very important, says Heidi May, PhD, MS, an epidemiologist with the Intermountain Medical Center research team and one of the study authors.

"We concluded that among patients 50 years of age or older, even a moderate deficiency of Vitamin D levels was linked to developing coronary artery disease, heart failure, stroke, and death," she says. "This is important because Vitamin D deficiency is easily treated. If increasing levels of Vitamin D can decrease some risk linked to these cardiovascular diseases, it could have a significant public health impact. When you consider that cardiovascular disease is the leading cause of death in America, you understand how this research can help improve the length and quality of people's lives".

Because the study was only observational, definitive links between Vitamin D deficiency and heart disease could not be assigned but the findings create an impetus for further study, says Dr. Muhlestein.

"We believe the findings are important enough to now justify randomized therapy trials of supplementation in patients with Vitamin D deficiency to determine for sure whether it can reduce the risk of heart disease," he says.


Posted by: Daniel    Source




Did you know?
While mothers have known that feeding their kids milk builds strong bones, a newly released study by scientists at the Heart Institute at Intermountain Medical Center in Salt Lake City suggests that Vitamin D contributes to a strong and healthy heart as well and that inadequate levels of the vitamin may significantly increase a person's risk of stroke, heart disease, and death, even among people who've never had heart disease.

Medicineworld.org: Vitamin D deficiency and cardiovascular disease

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