MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Folate intake may reduce colorectal cancer risk

Back to colon cancer blog Blogs list Cancer blog  


Subscribe To Colon Cancer Blog RSS Feed  RSS content feed What is RSS feed?

Folate intake may reduce colorectal cancer risk




A newly released study finds high folate intake is linked to a reduced risk of colorectal cancer, a finding consistent with the findings of most prior epidemiologic studies. The study is reassuring, as prior recent evidence has suggested that consumption of very high levels of folate through supplements and from folate-fortified diet may increase risk of some cancers. Nonetheless, the potential importance of folate in colorectal cancer prevention remains in question because at least one other study found folate supplementation had no effect on recurrence of colorectal adenomas, precursors to colorectal cancer.



Folate intake may reduce colorectal cancer risk

The study appears in Gastroenterology, and is the first to look at the association of folate with colorectal cancer risk with follow-up entirely after the required fortification of the U.S. diet with folate. It also is the first to distinguish between the forms of folate found naturally in forms and folic acid, the form used for fortification and in supplements.

A research team led by Victoria Stevens, Ph.D., strategic director of laboratory services at the American Cancer Society, investigated the association between folate intake and colorectal cancer among 99,523 participants in the Cancer Prevention Study II Nutrition Cohort. A total of 1,023 participants were diagnosed with colorectal cancer between 1999 and 2007, a period entirely after folate fortification began. Neither higher nor lower risk was observed during the first two years of follow-up (1999 to 2001), but during 2002 to 2007, high folate intake was linked to a reduced risk of colorectal cancer.

"While folate fortification has been a public health success in reducing the risk of neural tube defects, the potential for an increase risk of cancer has been legitimate," said Dr. Stevens. "Our study population included a number of participants who consumed these very high levels of folate and we found no increased risk of colorectal cancer in these individuals. Nonetheless, one randomized clinical trial failed to show folate supplementation reduced the risk of adenomas, the non-malignant colon polyps that can become malignant, so we need to continue to investigate the influence of folate on cancer development in high risk populations as well as potential differences in the action of natural and synthetic form of this vitamin".


Posted by: Sue    Source




Did you know?
A newly released study finds high folate intake is linked to a reduced risk of colorectal cancer, a finding consistent with the findings of most prior epidemiologic studies. The study is reassuring, as prior recent evidence has suggested that consumption of very high levels of folate through supplements and from folate-fortified diet may increase risk of some cancers. Nonetheless, the potential importance of folate in colorectal cancer prevention remains in question because at least one other study found folate supplementation had no effect on recurrence of colorectal adenomas, precursors to colorectal cancer.

Medicineworld.org: Folate intake may reduce colorectal cancer risk

Main Page| Cancer blog| Cancer blogs list| Lung cancer blog| Colon cancer blog| Prostate cancer blog| Breast cancer blog| Diabetes watch blog| Heart watch blog| Allergy blog| Bladder cancer blog| Cervical cancer blog| Colon cancer news blog| Diabetes news blog| Esophageal cancer blog| Gastric cancer blog| Health news blog| Heart news blog| Infectious disease blog| Kidney watch blog| Lung disease blog| Lung cancer news blog| Mesothelioma blog| Neurology blog| Breast cancer news blog| OBGYN blog| Ophthalmology blog| Ovarian cancer blog| Cancer news blog| Pancreas cancer blog| Pediatrics blog| Prostate cancer news blog| Psychology blog| Research blog| Rheumatology blog| Society news blog| Uterine cancer blog| Weight watch blog|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.