MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: 'Hygiene hypothesis' challenged

Back to allergy news Blogs list Cancer blog  


Subscribe To Allergy News RSS Feed  RSS content feed What is RSS feed?

'Hygiene hypothesis' challenged




New research hints that the common belief that kids who go to daycare have lower rates of asthma and allergy during the later part of life might be nothing more than wishful thinking. While young children in daycare definitely do get more illnesses and experience more respiratory symptoms as a result, any perceived protection these exposures afford against asthma and allergy seem to disappear by the time the child hits the age of eight.



'Hygiene hypothesis' challenged

"We found no evidence for a protective or harmful effect of daycare on the development of asthma symptoms, allergic sensitization, or airway hyper-responsiveness at the age of eight years," wrote Johan C de Jongste, M.D., Ph.D., of Erasmus University in the Netherlands and principle investigator of the study. "Early daycare was linked to more airway symptoms until the age of four years, and only in children without older siblings, with a transient decrease in symptoms between four and eight years".

The results are reported in the September 15 issue of the American Journal of Respiratory and Critical Care Medicine, a journal of the American Thoracic Society.

The scientists prospectively followed a birth cohort of nearly 4,000 Dutch children over the course of eight years in the Prevention and Occurence rate of Asthma and Mite Allergy (PIAMA) Study. Parents completed questionnaires during pregnancy, at three and 12 months, and then yearly until the child reached the age of eight, and reported their children's airway symptoms annually. At the age of eight, more than 3,500 of the children were also assessed for specific allergies. Some also underwent testing for lung function and airway hyper-responsiveness.

Daycare use was assessed each year, and the children were categorized in early attendees (first attendance before two years of age), late attendees (first attendance between two and four years of age) and non-attendees.

They observed that children who started daycare early were twice as likely to experience wheezing in the first year of life in comparison to those who didn't go to daycare. However, as the children aged, there was a shift: by age five, there was a trend for less wheezing among early attendees: they were about 80 percent as likely as non-attendees to wheeze, but this was not statistically significant. What's more, the shift reversed itself by age eight, when there was no association between early daycare attendance and wheezing at all.

Late daycare attendees had similar, but less pronounced and statistically nonsignificant effects. The effects of daycare on wheeze were not different between boys and girls, but were more marked in children with older siblings.

"Children with older siblings and early daycare had more than fourfold higher risk of frequent respiratory infections and more than twofold risk of wheezing in the first year in comparison to children without older siblings and daycare," said Dr. de Jongste. "Importantly, children exposed to both early daycare and older siblings experienced most infections and symptoms in early childhood, without a protective effect on wheeze, inhaled steroid prescription or asthma symptoms until the age of eight years".

Despite the widespread acceptance of the idea that these early exposures pay off in later health benefits, the data in this study do not support that belief. If anything, this study suggests that these exposures cause more airway symptoms early in life with no counterbalancing benefit later.

"Early daycare merely seems to shift the burden of respiratory morbidity to an earlier age where it is more troublesome than at a later age," said Dr. de Jongste. "[E]arly daycare should not be promoted for reasons of preventing asthma and allergy".


Posted by: JoAnn    Source




Did you know?
New research hints that the common belief that kids who go to daycare have lower rates of asthma and allergy during the later part of life might be nothing more than wishful thinking. While young children in daycare definitely do get more illnesses and experience more respiratory symptoms as a result, any perceived protection these exposures afford against asthma and allergy seem to disappear by the time the child hits the age of eight.

Medicineworld.org: 'Hygiene hypothesis' challenged

Asthma| Hypertension| Medicine| Allergy statistics| How to create a dust free bedroom|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.