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Medicineworld.org: Predicting weight regain after dieting

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Predicting weight regain after dieting




A number of people have experienced the frustration that comes with regaining weight that was lost from dieting. As per a newly released study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), the levels of appetite hormones in the body previous to dieting may serve as a predictor of weight regain after dieting.



Predicting weight regain after dieting

"Treating obesity with drugs or dietary programs can be very effective in the short-term, but the long-term success of maintaining the weight lost is commonly poor," said Ana Crujeiras, PhD, of Compejo Hospitalario Universitario de Santiago in Spain and main author of the study. "Our study sheds light on how the appetite hormones leptin and ghrelin affect weight regain after weight loss. This knowledge could be used as a tool to personalize weight-loss programs that could guarantee success in keeping off the weight".

In this study, scientists reviewed a group of 104 obese or overweight men and women during an 8-week low-calorie diet and again 32 weeks after therapy. Scientists measured body weight as well as plasma fasting ghrelin, leptin and insulin concentrations before, during and after dieting. They observed that subjects with higher plasma leptin and lower ghrelin levels before dieting were more prone to regain weight lost after dieting and that these hormone levels could be proposed as biomarkers for predicting obesity-treatment outcomes.

"We believe this research is of foremost relevance in clinical terms as it may indicate that the outcome of weight treatment appears to be pre-conditioned," said Crujeiras. "Furthermore, our findings may provide endocrinology and nutrition professionals a tool to identify individuals in need of specialized weight-loss programs that first target appetite hormone levels before beginning conventional dietary therapy".


Posted by: JoAnn    Source




Did you know?
A number of people have experienced the frustration that comes with regaining weight that was lost from dieting. As per a newly released study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM), the levels of appetite hormones in the body previous to dieting may serve as a predictor of weight regain after dieting.

Medicineworld.org: Predicting weight regain after dieting

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