http://medicineworld.org/news/pancreasnews.html MedicineWorld.Org brings daily pancreatic cancer news from various sources to keep you updated on the latest events in the world on this topic. Medicineworld heart watch news service is the most comprehensive heart watch news service on the internet. We keep an archive of previous few days of news on this site. Please go down through the list to find the older news items. Wed, 16 Mar 2011 04:22:16 GMT en-us http://medicineworld.org/images/pancreas.jpg http://medicineworld.org/news/pancreasnews.html 96 77 http://medicineworld.org/stories/lead/3-2011/malaria-drug-for-pancreatic-cancer.html http://medicineworld.org/stories/lead/3-2011/malaria-drug-for-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Researchers report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis. The pre-clinical results, which will appear in the recent issue of the journal Genes and Development and is currently published on its web site, have already prompted the opening of a small clinical trial in patients with advanced pancreas cancer, one of the deadliest and hardest-to-treat forms of cancer, said the investigators, led by Alec Kimmelman, MD, PhD, a radiation oncologist at Dana-Farber........ ]]> http://medicineworld.org/stories/lead/1-2011/genetic-code-for-form-of-pancreatic-cancer.html http://medicineworld.org/stories/lead/1-2011/genetic-code-for-form-of-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Researchers at Johns Hopkins have deciphered the genetic code for a type of pancreas cancer, called neuroendocrine or islet cell tumors. The work, described online in the Jan. 20 issue of Science Express, shows that patients whose tumors have certain coding "mistakes" live twice as long as those without them........ ]]> http://medicineworld.org/stories/lead/6-2010/treatment-of-pancreatic-adenocarcinoma.html http://medicineworld.org/stories/lead/6-2010/treatment-of-pancreatic-adenocarcinoma.html Wed, 16 Mar 2011 04:22:16 GMT Pancreatic ductal adenocarcinoma (PDAC) is a highly cancerous digestive tumor with a very poor prognosis. Hypoxia-inducible transcription factor-1and#945; (HIF-1and#945;) is involved in cancerous progression in a number of solid tumors, including PDAC, upregulation of HIF-1and#945; accelerates PDAC progression, but the exact regulatory mechanisms of HIF-1and#945;in PDAC has not been unequivocally addressed. Recently, an increasing number of studies reported that toll-like receptors (TLRs) were upregulated in epithelial malignancies and involved in tumor progression, but whether TLRs, such as TLR4, is expressed on PDAC cells remains unknown. In immune-related cells, TLR signal pathway may induce expression of HIF-1and#945;, but it is also still unclear whether there exists some association between TLR4 and HIF-1and#945; in tumor microenviroment, such as PDAC........ ]]> http://medicineworld.org/stories/lead/6-2010/is-that-cyst-pancreatic-cancer.html http://medicineworld.org/stories/lead/6-2010/is-that-cyst-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Working with scientists from the University of Michigan and Indiana University, Van Andel Research Institute (VARI) researchers have developed a method that could be used to predict whether pancreatic cysts are non-malignant or are precursors to invasive cancer. More pancreatic cysts are being detected due to the widespread use of high resolution abdominal imaging. These advances in early detection, when coupled with the new findings, could result in fewer deaths from pancreas cancer, which struck more than 42,000 Americans in 2009 and killed more than 35,000, as per the National Cancer Institute........ ]]> http://medicineworld.org/stories/lead/3-2010/synthetic-compound-for-pancreatic-cancers.html http://medicineworld.org/stories/lead/3-2010/synthetic-compound-for-pancreatic-cancers.html Wed, 16 Mar 2011 04:22:16 GMT Human pancreas cancer cells dramatically regress when treated with chemotherapy in combination with a synthetic compound that mimics the action of a naturally occurring "death-promoting" protein found in cells, scientists at UT Southwestern Medical Center have found. The research, conducted in mice, appears in today's issue of Cancer Research and could lead to more effective therapies for pancreatic and possibly other cancers, the scientists said........ ]]> http://medicineworld.org/stories/lead/2-2010/soft-drink-consumption-and-pancreatic-cancer.html http://medicineworld.org/stories/lead/2-2010/soft-drink-consumption-and-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Consuming two or more soft drinks per week increased the risk of developing pancreatic cancer by nearly twofold compared to individuals who did not consume soft drinks, according to a report in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research........ ]]> http://medicineworld.org/stories/lead/1-2010/how-pancreatic-cancer-able-to-defeat-drugs.html http://medicineworld.org/stories/lead/1-2010/how-pancreatic-cancer-able-to-defeat-drugs.html Wed, 16 Mar 2011 04:22:16 GMT Scientists at the Moores Cancer Center at the University of California, San Diego, have found one reason that pancreas cancer tumors are so difficult to treat with drugs. They have shown how a molecular switch steps up pancreas cancer cell survival as well as resistance to a standard chemotherapy drug, and have identified alternate routes cancer cells take to avoid the effects of the treatment........ ]]> http://medicineworld.org/stories/lead/11-2009/pancreatic-cancer-risk.html http://medicineworld.org/stories/lead/11-2009/pancreatic-cancer-risk.html Wed, 16 Mar 2011 04:22:16 GMT A Henry Ford Hospital study observed that hepatitis B does not increase the risk for pancreas cancer and that only age is a contributing factor. The results contradict a prior study in 2008 that suggested a link between pancreas cancer and prior hepatitis B infection. Hepatitis B is an inflammation of the liver caused by a viral infection........ ]]> http://medicineworld.org/stories/lead/9-2009/progress-in-pancreatic-cancer.html http://medicineworld.org/stories/lead/9-2009/progress-in-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT For the first time scientists have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreas cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. Dr Davide Melisi told Europe's largest cancer congress, ECCO 15 ESMO 34 [1], in Berlin today (Thursday 24 September) that resistance to chemotherapy was the greatest challenge to treating pancreas cancer........ ]]> http://medicineworld.org/stories/lead/8-2009/metformin-reduces-risk-of-pancreatic-cancer.html http://medicineworld.org/stories/lead/8-2009/metformin-reduces-risk-of-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Taking the most commonly-prescribed anti-diabetic drug, metformin, reduces an individual's risk of developing pancreas cancer by 62 percent, as per research from The University of Texas M. D. Anderson Cancer Center, reported in the Aug. 1 issue of Gastroenterology "This is the first epidemiological study of metformin in the cancer population, and it offers an exciting direction for future chemoprevention research for a disease greatly in need of both therapy and prevention strategies," said Donghui Li, Ph.D., professor in M. D. Anderson's Department of Gastrointestinal Medical Oncology........ ]]> http://medicineworld.org/stories/lead/7-2009/metastatic-pancreatic-cancer.html http://medicineworld.org/stories/lead/7-2009/metastatic-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, as per scientists from the Kimmel Cancer Center at Jefferson. Their study was reported in the August edition of the journal Surgery....... ]]> http://medicineworld.org/stories/lead/4-2009/herbal-extra-to-against-pancreatic-cancer.html http://medicineworld.org/stories/lead/4-2009/herbal-extra-to-against-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT An herb recently found to kill pancreas cancer cells also appears to inhibit development of pancreas cancer as a result of its anti-inflammatory properties, as per scientists from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #494)........ ]]> http://medicineworld.org/stories/lead/4-2009/finding-pancreatic-cancer-early.html http://medicineworld.org/stories/lead/4-2009/finding-pancreatic-cancer-early.html Wed, 16 Mar 2011 04:22:16 GMT A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreas cancer........ ]]> http://medicineworld.org/stories/lead/2-2009/determining-risk-for-pancreatic-cancer.html http://medicineworld.org/stories/lead/2-2009/determining-risk-for-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT In the latest clinical trial for a technique to detect pancreas cancer, scientists found they could differentiate cells that are malignant from those that are benign, pre-malignant, or even early stage indicators called mucinous cystic lesions. Pancreas cancer is dangerous to screen for, yet deadly if ignored. The pancreas is extremely sensitive--biopsies can lead to potentially fatal complications--but with few symptoms, the cancer is commonly detected too late........ ]]> http://medicineworld.org/stories/lead/1-2009/genes-and-pancreatic-cancer.html http://medicineworld.org/stories/lead/1-2009/genes-and-pancreatic-cancer.html Wed, 16 Mar 2011 04:22:16 GMT Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreas cancer, a research team from The University of Texas M. D. Anderson Cancer Center reports in the Jan. 15 issue of Clinical Cancer Research Defects in these critical DNA repair genes may act alone or in combination with traditional risk factors known to increase an individual's likelihood of being diagnosed with this very aggressive type of cancer........ ]]>